Ionizing radiation and inhibition of angiogenesis in a spontaneous mammary carcinoma and in a syngenic heterotopic allograft tumor model: a comparative study

Autor: Martin Pruschy, Angela Broggini-Tenzer, Christoph Oehler-Jänne, Wolfram Jochum, Van Vuong, Oliver Riesterer

Publikováno v: Radiation Oncology (London, England)
Radiation Oncology, Vol 6, Iss 1, p 66 (2011)

Background The combined treatment modality of ionizing radiation (IR) with inhibitors of angiogenesis (IoA) is a promising treatment modality based on preclinical in vivo studies using heterotopic xeno- and allograft tumor models. Nevertheless reserv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b190d0eb5357562f6217832174087bf7
https://doi.org/10.1186/1748-717x-6-66

RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

Autor: Michael A. Grotzer, Christoph Oehler-Jänne, Tarek Shalaby, Martin Pruschy, Alexandre Arcaro, Duncan Stearns, Charles G. Eberhart, Lucia Arnold, André O. von Bueren

Publikováno v: BMC Cancer
BMC cancer, Vol. 9 (2009) P. 10
von Bueren, André O; Shalaby, Tarek; Oehler-Jänne, Christoph; Arnold, Lucia; Stearns, Duncan; Eberhart, Charles G; Arcaro, Alexandre; Pruschy, Martin; Grotzer, Michael A (2009). RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio-and chemotherapy in childhood medulloblastoma cells. BMC cancer, 9, p. 10. London: BioMed Central 10.1186/1471-2407-9-10
BMC Cancer, Vol 9, Iss 1, p 10 (2009)

BackgroundWith current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6876b3be6926450ad1dd12ea1060409
https://doi.org/10.5167/uzh-28400

HIV-specific differences in outcome of squamous cell carcinoma of the anal canal: a multicentric cohort study of HIV-positive patients receiving highly active antiretroviral therapy

Autor: Sawyna Provencher, Florence Huguet, I. Frank Ciernik, Abdelkarim S. Allal, Burkhardt Seifert, Marc-Oliver Riener, Christoph Oehler-Jänne, Laura Negretti, Marta Bonet

Publikováno v: Journal of Clinical Oncology, Vol. 26, No 15 (2008) pp. 2550-7

Purpose To define clinical outcome after definitive chemoradiotherapy (CRT) of anal carcinoma in HIV-infected patients treated with highly active antiretroviral therapy (HAART). Patients and Methods A multicentric cohort comparison of 40 HIV-positive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1850976ef7d152b416d7e5dfda045a48
https://archive-ouverte.unige.ch/unige:1781

Hypoxia modulation and radiosensitization by the novel dual EGFR and VEGFR inhibitor AEE788 in spontaneous and related allograft tumor models

Autor: Wolfram Jochum, Giorgio Caravatti, Christoph Oehler-Jänne, Oliver Riesterer, Van Vuong, Angela Broggini-Tenzer, Martin Pruschy

Concomitant inhibition of ErbB1/2- and VEGF receptor-signaling synergizes when used in combination with DNA-damaging agents. Here, we investigated for the first time the combined treatment modality of the novel dual specific receptor tyrosine kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c074d2f1c810b3464dc746304b3cb5a6
https://doi.org/10.5167/uzh-111762