Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christoph Meinken"'
Autor:
Heiko Bruns, Robert L. Modlin, Philipp Schauenberg, Peter Kern, Steffen Stenger, Georg Härter, Christian Antoni, Christoph Meinken
Publikováno v:
Journal of Clinical Investigation. 119:1167-1177
The incidence of tuberculosis is increased during treatment of autoimmune diseases with anti-TNF antibodies. This is a significant clinical complication, but also provides a unique model to study immune mechanisms in human tuberculosis. Given the key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65183866bfe088930795105938db0237
https://doi.org/10.1172/jci38482
https://doi.org/10.1172/jci38482
Autor:
George J. Cianciolo, Maike Buettner, Rauf Bhat, Manfred Wagner, Joachim H. Ficker, Elmar Stössel, Steffen Stenger, Christoph Meinken, Max Bastian, Martin Röllinghoff, Gerhard Faller
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Dendritic cells (DCs) are a key part of host defense against microbial pathogens, being part of the innate immune system, but also instructing the adaptive T cell response. This study was designed to evaluate whether human DCs directly contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b800047bd718b45dd66f8008d1dab989
https://doi.org/10.4049/jimmunol.174.7.4203
https://doi.org/10.4049/jimmunol.174.7.4203
Autor:
Manfred Wagner, Christoph Meinken, Euzenir Nunes Sarno, Masahiro Yamamura, Barry R. Bloom, Anne E. Burdick, Robert L. Modlin, Martin Röllinghoff, Marco Colonna, David Eisenberg, Thomas H. Rea, Steffen Stenger, Joshua R. Bleharski, Thomas G. Graeber, Maria Teresa Ochoa, Huiying Li
Publikováno v:
Science. 301:1527-1530
Leprosy presents as a clinical and immunological spectrum of disease. With the use of gene expression profiling, we observed that a distinction in gene expression correlates with and accurately classifies the clinical form of the disease. Genes belon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8390c6e6b766084c75e8d0e0306dafd9
https://doi.org/10.1126/science.1087785
https://doi.org/10.1126/science.1087785
Publikováno v:
Microbiology. 149:751-761
Glycolysis is one of the central routes of carbon catabolism in Bacillus subtilis. Several glycolytic enzymes, including the key enzyme glyceraldehyde-3-phosphate dehydrogenase, are encoded in the hexacistronic gapA operon. Expression of this operon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ef6993715f29bb3124725acd7459ee
https://doi.org/10.1099/mic.0.26078-0
https://doi.org/10.1099/mic.0.26078-0
Autor:
Stephan R. Krutzik, Max Bastian, Annaliza J. Legaspi, Belinda H. Tan, Christoph Meinken, Heiko Bruns, Steffen Stenger, Barry R. Bloom, Tomas Ganz, Maria Teresa Ochoa, Robert L. Modlin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(3)
A key target of many intracellular pathogens is the macrophage. Although macrophages can generate antimicrobial activity, neutrophils have been shown to have a key role in host defense, presumably by their preformed granules containing antimicrobial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74a95db2a024f6451e06f5d2220150
https://pubmed.ncbi.nlm.nih.gov/16849498
https://pubmed.ncbi.nlm.nih.gov/16849498
Autor:
David Eisenberg, Huiying Li, Steffen Stenger, Diane L. Kamen, Jürgen Schauber, Martin Hewison, Richard L. Gallo, Robert Bals, Robert L. Modlin, Kent Wu, Christoph Meinken, Philip T. Liu, Barry R. Bloom, Bruce W. Hollis, John S. Adams, Manfred Wagner, Linda Wenzel, Stephan R. Krutzik, Ulrich Zügel, Belinda H. Tan, Maria Teresa Ochoa, Andreas Steinmeyer
Publikováno v:
Science (New York, N.Y.). 311(5768)
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbf8d756320c5a214ca475e4c62c9e6
https://pubmed.ncbi.nlm.nih.gov/16809512
https://pubmed.ncbi.nlm.nih.gov/16809512
Publikováno v:
Journal of bacteriology. 184(18)
Bacillus subtilis ccpA mutant strains exhibit two distinct phenotypes: they are defective in catabolite repression, and their growth on minimal media is strongly impaired. This growth defect is largely due to a lack of expression of the gltAB operon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04daf5002f1372883b07adccf56ac4da
https://pubmed.ncbi.nlm.nih.gov/12193635
https://pubmed.ncbi.nlm.nih.gov/12193635