Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christoph Matti"'
Autor:
Nicolas Garcia-Seyda, Solene Song, Valentine Seveau de Noray, Luc David-Broglio, Christoph Matti, Marc Artinger, Florian Dupuy, Martine Biarnes-Pelicot, Marie-Pierre Valignat, Daniel F. Legler, Marc Bajénoff, Olivier Theodoly
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107695- (2023)
Summary: Naive T lymphocytes traffic through the organism in search for antigen, alternating between blood and secondary lymphoid organs. Lymphocyte homing to lymph nodes relies on CCL21 chemokine sensing by CCR7 receptors, while exit into efferent l
Externí odkaz:
https://doaj.org/article/80cc1697d0144c61ae87a4ccce1aa50b
Autor:
Christoph Matti, Angela Salnikov, Marc Artinger, Gianluca D'Agostino, Ilona Kindinger, Mariagrazia Uguccioni, Marcus Thelen, Daniel F. Legler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chemokines are essential for guiding cell migration. Atypical chemokine receptors (ACKRs) contribute to the cell migration process by binding, internalizing and degrading local chemokines, which enables the formation of confined gradients. ACKRs are
Externí odkaz:
https://doaj.org/article/0a8250a32de1472e87c1651b12256ec3
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4158 (2021)
Chemokines guide leukocyte migration in different contexts, including homeostasis, immune surveillance and immunity. The chemokines CCL19 and CCL21 control lymphocyte and dendritic cell migration and homing to lymphoid organs. Thereby they orchestrat
Externí odkaz:
https://doaj.org/article/6da2e3e53eee4c8f9cbd21bd84653377
Autor:
Barbara D. Jakobs, Lisa Spannagel, Vladimir Purvanov, Edith Uetz-von Allmen, Christoph Matti, Daniel F. Legler
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2597 (2019)
The chemokine receptor CCR7 plays a pivotal role in health and disease. In particular, CCR7 controls homing of antigen-bearing dendritic cells and T cells to lymph nodes, where adaptive immune responses are initiated. However, CCR7 also guides T cell
Externí odkaz:
https://doaj.org/article/9490b0b1526c4c1f9e1e7bca6c8539db
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3876 (2018)
Chemokines are essential guidance cues orchestrating cell migration in health and disease. Cognate chemokine receptors sense chemokine gradients over short distances to coordinate directional cell locomotion. The chemokines CCL19 and CCL21 are essent
Externí odkaz:
https://doaj.org/article/3b3090c3db654ed8b43ba141ec284a00
Autor:
Nicolas Garcia-Seyda, Solene Song, Luc David-Broglio, Christoph Matti, Marc Artinger, Martine Biarnes-Pelicot, Marie-Pierre Valignat, Daniel F. Legler, Marc Bajénoff, Olivier Theodoly
SummaryNaïve T lymphocytes traffic through the organism in their search for antigen, alternating between blood and secondary lymphoid organs. Lymphocyte homing to lymph nodes relies on the chemokine CCL21, while exit into efferent lymphatics relies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d39fd115863797fd54e2b525cc4813
https://doi.org/10.1101/2023.02.03.526993
https://doi.org/10.1101/2023.02.03.526993
Autor:
Jonathan A. Javitch, Christoph Matti, Natasha L. Grimsey, David B. Finlay, Daniel F. Legler, Michelle Glass, Monica Patel
Publikováno v:
British Journal of Pharmacology. 179:2223-2239
BACKGROUND AND PURPOSE The cannabinoid CB2 receptor (CB2 ) is a promising therapeutic target for modulating inflammation. However, little is known surrounding the mechanisms underpinning CB2 desensitisation and regulation, particularly the role of G
Autor:
Mona C. Friess, Ioannis Kritikos, Philipp Schineis, Jessica Danielly Medina-Sanchez, Anastasia-Olga Gkountidi, Angela Vallone, Elena C. Sigmund, Corina Schwitter, Martina Vranova, Christoph Matti, Jorge Arasa, Cansaran Saygili Demir, Esther Bovay, Steven T. Proulx, Michio Tomura, Antal Rot, Daniel F. Legler, Tatiana V. Petrova, Cornelia Halin
Publikováno v:
Cell Reports, 38 (5)
Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334
Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334
T cell migration via afferent lymphatics to draining lymph nodes (dLNs) depends on expression of CCR7 in T cells and CCL21 in the lymphatic vasculature. Once T cells have entered lymphatic capillaries, they slowly migrate into contracting collecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51c1dcb4ca476e8a49312f08b854f8f
Autor:
Monica, Patel, Christoph, Matti, Natasha L, Grimsey, Daniel F, Legler, Jonathan A, Javitch, David B, Finlay, Michelle, Glass
Publikováno v:
British journal of pharmacologyREFERENCES. 179(10)
The cannabinoid CBIn CBOverexpression of GRK isoforms 1-6 failed to considerably improve translocation of either β-arrestin 1 or β-arrestin 2 to CBOur findings suggest that CB
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4158, p 4158 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 4158, p 4158 (2021)
Volume 22
Issue 8
Chemokines guide leukocyte migration in different contexts, including homeostasis, immune surveillance and immunity. The chemokines CCL19 and CCL21 control lymphocyte and dendritic cell migration and homing to lymphoid organs thereby orchestrating ad