Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christoph Malisi"'
Autor:
Maura John, Florian Haselbeck, Rupashree Dass, Christoph Malisi, Patrizia Ricca, Christian Dreischer, Sebastian J. Schultheiss, Dominik G. Grimm
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Genomic selection is an integral tool for breeders to accurately select plants directly from genotype data leading to faster and more resource-efficient breeding programs. Several prediction methods have been established in the last few years. These
Externí odkaz:
https://doaj.org/article/1989c900845642afbd2043b4c21e4580
Autor:
Christoph Malisi, Marcel Schumann, Nora C Toussaint, Jorge Kageyama, Oliver Kohlbacher, Birte Höcker
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52505 (2012)
Engineering specific interactions between proteins and small molecules is extremely useful for biological studies, as these interactions are essential for molecular recognition. Furthermore, many biotechnological applications are made possible by suc
Externí odkaz:
https://doaj.org/article/6415dc7ff57544f2bda97d1adb5d590b
Autor:
Birte Höcker, Sandra Schlee, Reinhard Sterner, Nicholas G. Fox, Frank M. Raushel, Chitra Rajendran, David P. Barondeau, Chengfu Xu, Monika M. Meier, Christoph Malisi
Publikováno v:
Journal of the American Chemical Society. 135:11670-11677
Rapid evolution of enzymes provides unique molecular insights into the remarkable adaptability of proteins and helps to elucidate the relationship between amino acid sequence, structure, and function. We interrogated the evolution of the phosphotries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5613289f57135de5eba6bac79c0f2283
https://doi.org/10.1021/ja405911h
https://doi.org/10.1021/ja405911h
Publikováno v:
Proteins. 77(1)
A major goal of computational protein design is the construction of novel functions on existing protein scaffolds. There the first question is which scaffold is suitable for a specific reaction. Given a set of catalytic residues and their spatial arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac19cc30b93cd3b0c7b4314a174fa7d
https://pubmed.ncbi.nlm.nih.gov/19408301
https://pubmed.ncbi.nlm.nih.gov/19408301
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(10)
The generation of high levels of new catalytic activities on natural and artificial protein scaffolds is a major goal of enzyme engineering. Here, we used random mutagenesis and selection in vivo to establish a sugar isomerisation reaction on both a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0062b59ebf11d80f8b0f5f43767a77cc
https://pubmed.ncbi.nlm.nih.gov/19237570
https://pubmed.ncbi.nlm.nih.gov/19237570