Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Christoph M. Tang"'
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTNeisseria gonorrhoeae causes sexually transmitted infection (STI) gonorrhoea and is on the WHO critical list due to increasing antimicrobial resistance (AMR). The bacterium can carry a conjugative plasmid, pConj, which prevents the use of tet
Externí odkaz:
https://doaj.org/article/bcc701fab6974d8299d2c069174a4a61
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-11 (2022)
Abstract Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties, and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT). Multidrug resistance in bacteria, especially in Gram-negativ
Externí odkaz:
https://doaj.org/article/d5134c4c31ad4284b79cb6dbaa5a1daf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that have evolved to be uniquely adapted to their host. The meningococcus is frequently carried asymptomatically in the nasopharynx, while gonococcal infection of the u
Externí odkaz:
https://doaj.org/article/bc051f35d43341d4acbd2c7109ef12c0
Autor:
Yang Su, Jianhui Li, Wenting Zhang, Jinjing Ni, Rui Huang, Zuoqiang Wang, Sen Cheng, Yue Wang, Zhixin Tian, Qiuxiang Zhou, Donghai Lin, Wenjuan Wu, Christoph M. Tang, Xiaoyun Liu, Jie Lu, Yu-Feng Yao
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response reg
Externí odkaz:
https://doaj.org/article/19f014700315414cbc5144d4ac08ed96
Autor:
Emeline Lawarée, Gytis Jankevicius, Charles Cooper, Ivan Ahel, Stephan Uphoff, Christoph M. Tang
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1373-1384.e4 (2020)
Summary: ADP-ribosylation of proteins is crucial for fundamental cellular processes. Despite increasing examples of DNA ADP-ribosylation, the impact of this modification on DNA metabolism and cell physiology is unknown. Here, we show that the DarTG t
Externí odkaz:
https://doaj.org/article/3e3003a16285442cb7ec8d952a71ba36
Autor:
Giulia Pilla, Tao Wu, Christen Grassel, Jonathan Moon, Jennifer Foulke-Abel, Christoph M. Tang, Eileen M. Barry
Publikováno v:
Pathogens, Vol 10, Iss 9, p 1079 (2021)
Shigella is a leading cause of bacillary dysentery worldwide, responsible for high death rates especially among children under five in low–middle income countries. Shigella sonnei prevails in high-income countries and is becoming prevalent in indus
Externí odkaz:
https://doaj.org/article/c79461ec0421489d93f1b7bed99aaaa9
Autor:
Benoit S. Marteyn, Gouzel Karimova, Andrew K. Fenton, Anastasia D. Gazi, Nicholas West, Lhousseine Touqui, Marie-Christine Prevost, Jean-Michel Betton, Oemer Poyraz, Daniel Ladant, Kenn Gerdes, Philippe J. Sansonetti, Christoph M. Tang
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Bacterial cell division requires the formation of a mature divisome complex positioned at the midcell. The localization of the divisome complex is determined by the correct positioning, assembly, and constriction of the FtsZ ring (Z-ring). Z
Externí odkaz:
https://doaj.org/article/09defa5ffaca4dcfae9eb606c7f4b51b
Autor:
Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J. Harding, Xilian Bai, Rachel M. Exley, Philip N. Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C. Pickering, Susan M. Lea, Christoph M. Tang
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/320055d2ea744119955e12185bfac800
Publikováno v:
Infection and immunity. 90(10)
Neisseria meningitidis and Neisseria gonorrhoeae are important human pathogens that have evolved to bind the major negative regulator of the complement system, complement factor H (CFH). However, little is known about the interaction of pathogens wit
Publikováno v:
Microbiology. 168
Neisseria gonorrhoeae , the gonococcus, is a pathogen of major public health concern, but sophisticated approaches to gene manipulation are limited for this species. For example, there are few methods for generating markerless mutations, which allow