Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Christoph Kreutz"'
Autor:
Raphael Haslecker, Vincent V. Pham, David Glänzer, Christoph Kreutz, Theodore Kwaku Dayie, Victoria M. D’Souza
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract RNA performs a wide range of functions regulated by its structure, dynamics, and often post-transcriptional modifications. While NMR is the leading method for understanding RNA structure and dynamics, it is currently limited by the inability
Externí odkaz:
https://doaj.org/article/0eec05fa87c24e6c858477c204ea4afb
Autor:
Hyeong Jin Kim, Mazzen Black, Ross A. Edwards, Flora Peillard-Fiorente, Rashmi Panigrahi, David Klingler, Reiner Eidelpes, Ricarda Zeindl, Shiyun Peng, Jikun Su, Ayat R. Omar, Andrew M. MacMillan, Christoph Kreutz, Martin Tollinger, Xavier Charpentier, Laetitia Attaiech, J. N. Mark Glover
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In this work, the authors determine the crystal structure of a ProQ/FinO RNA chaperone bound to its RNA target. This provides insight into how this family of bacterial proteins recognize transcriptional terminator structures.
Externí odkaz:
https://doaj.org/article/ed2f8557c2fb4c6eb131771b7b1f7a50
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100077- (2022)
In this work a rapid RNA assignment approach by combining chemical and enzymatic 13C and 15N stable isotope labeling is introduced. We exemplify the assignment strategy for imino N1H1 purine and N3H3 pyrimidine and aromatic C6H6 pyrimidine, C8H8 puri
Externí odkaz:
https://doaj.org/article/5f8f55f29ec24d0cb0b098740b0b931f
Autor:
Bei Liu, Honglue Shi, Atul Rangadurai, Felix Nussbaumer, Chia-Chieh Chu, Kevin Andreas Erharter, David A. Case, Christoph Kreutz, Hashim M. Al-Hashimi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
m6A RNA post-transcriptional modification changes RNA hybridization kinetics. Here the authors show that the methylamino group can adopt syn-conformation pairing with uridine with a mismatch-like conformation in RNA duplex. They also develop a quanti
Externí odkaz:
https://doaj.org/article/82625506d090481bad2beca7aff5481e
Autor:
Eva-Maria Schneeberger, Matthias Halper, Michael Palasser, Sarah Viola Heel, Jovana Vušurović, Raphael Plangger, Michael Juen, Christoph Kreutz, Kathrin Breuker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The HIV-1 RNA-binding protein rev facilitates nuclear export of viral RNA. Here, the authors use native mass spectrometry to study the interactions between rev-derived peptides and rev response elements of HIV-1 RNA, providing mechanistic insights in
Externí odkaz:
https://doaj.org/article/13e70d04a2b44c299060a0fd63802d9e
Autor:
Gabriel Partl, Marcus Rauter, Lukas Fliri, Thomas Gelbrich, Christoph Kreutz, Thomas Müller, Volker Kahlenberg, Sven Nerdinger, Herwig Schottenberger
Publikováno v:
Molecules, Vol 27, Iss 13, p 4137 (2022)
3-(1H,1H,2H,2H-Perfluorooctyl)-1-vinylimidazolium chloride [2126844–17–3], a strong fluorosurfactant with remarkably high solubility in water, was expediently converted into the respective doubly NHC-complexed silver salt with nitrate as counter
Externí odkaz:
https://doaj.org/article/023f36da96d44fb0ba2dfb2b166f5327
Autor:
Thomas Philipp Hoernes, Klaus Faserl, Michael Andreas Juen, Johannes Kremser, Catherina Gasser, Elisabeth Fuchs, Xinying Shi, Aaron Siewert, Herbert Lindner, Christoph Kreutz, Ronald Micura, Simpson Joseph, Claudia Höbartner, Eric Westhof, Alexander Hüttenhofer, Matthias David Erlacher
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The recognition of the mRNA codon by the tRNA anticodon is crucial for protein synthesis. Here the authors introduce non-standard nucleotides in bacterial and eukaryotic mRNA to reveal the minimal hydrogen bond requirement of codon-anticodon interact
Externí odkaz:
https://doaj.org/article/ffffbc1b3a5340bdb59935247e94c0d4
Autor:
Bei Liu, Dawn K. Merriman, Seung H. Choi, Maria A. Schumacher, Raphael Plangger, Christoph Kreutz, Stacy M. Horner, Kate D. Meyer, Hashim M. Al-Hashimi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
N 6-Methyladenosine (m6A) is a post-transcriptional RNA modification that modulates RNA structure through a destabilization of m6A base pairing. Here the authors use NMR and UV melting experiments and show that m6A can also stabilize m6A–U base pai
Externí odkaz:
https://doaj.org/article/372622a59f9c424c8a4a6aac13ebbfc3
m6A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB.
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0224850 (2019)
N6-methyladenosine (m6A) is a ubiquitous RNA post-transcriptional modification found in coding as well as non-coding RNAs. m6A has also been found in viral RNAs where it is proposed to modulate host-pathogen interactions. Two m6A sites have been repo
Externí odkaz:
https://doaj.org/article/44959d3a188c44ba858c67cd78735745
Autor:
Hao-Che Peng, Gabrielle L. Castro, Varshini Karthikeyan, Alina Jarrett, Melanie A. Katz, James A. Hargrove, David Hoang, Stefan Hilber, Wenting Meng, Lu Wang, Robert J. Fick, Jung-Mo Ahn, Christoph Kreutz, Allison L. Stelling
Publikováno v:
The Journal of Physical Chemistry Letters. 14:4313-4321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b841091df4df539e025e5b9674b8f7d
https://doi.org/10.1021/acs.jpclett.3c00178
https://doi.org/10.1021/acs.jpclett.3c00178