Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Christoph Konradt"'
Autor:
Yibo Yin, Alina C. Boesteanu, Zev A. Binder, Chong Xu, Reiss A. Reid, Jesse L. Rodriguez, Danielle R. Cook, Radhika Thokala, Kristin Blouch, Bevin McGettigan-Croce, Logan Zhang, Christoph Konradt, Alexandria P. Cogdill, M. Kazim Panjwani, Shuguang Jiang, Denis Migliorini, Nadia Dahmane, Avery D. Posey, Jr., Carl H. June, Nicola J. Mason, Zhiguo Lin, Donald M. O’Rourke, Laura A. Johnson
Publikováno v:
Molecular Therapy: Oncolytics, Vol 11, Iss , Pp 20-38 (2018)
We generated two humanized interleukin-13 receptor α2 (IL-13Rα2) chimeric antigen receptors (CARs), Hu07BBz and Hu08BBz, that recognized human IL-13Rα2, but not IL-13Rα1. Hu08BBz also recognized canine IL-13Rα2. Both of these CAR T cell construc
Externí odkaz:
https://doaj.org/article/c4f59e6339ce4efa84b3ecf00abab181
Autor:
Arielle Glatman Zaretsky, Christoph Konradt, Fabien Dépis, James B. Wing, Radhika Goenka, Daniela Gomez Atria, Jonathan S. Silver, Sunglim Cho, Amaya I. Wolf, William J. Quinn, Julie B. Engiles, Dorothy C. Brown, Daniel Beiting, Jan Erikson, David Allman, Michael P. Cancro, Shimon Sakaguchi, Li-Fan Lu, Christophe O. Benoist, Christopher A. Hunter
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1906-1916 (2017)
Long-lived plasma cells (PCs) in the bone marrow (BM) are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs an
Externí odkaz:
https://doaj.org/article/76982e31a7d64e0c90b378be372684ec
Autor:
Shinya Hidano, Louise M. Randall, Lucas Dawson, Hans K. Dietrich, Christoph Konradt, Peter J. Klover, Beena John, Tajie H. Harris, Qun Fang, Bradley Turek, Takashi Kobayashi, Lothar Hennighausen, Daniel P. Beiting, Anita A. Koshy, Christopher A. Hunter
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT The local production of gamma interferon (IFN-γ) is important to control Toxoplasma gondii in the brain, but the basis for these protective effects is not fully understood. The studies presented here reveal that the ability of IFN-γ to inh
Externí odkaz:
https://doaj.org/article/b1805e78fdca4cabb73b13758748f715
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85763 (2014)
T. gondii uses substrate-dependent gliding motility to invade cells of its hosts, egress from these cells at the end of its lytic cycle and disseminate through the host organism during infection. The ability of the parasite to move is therefore criti
Externí odkaz:
https://doaj.org/article/676b942bebf444babb2045a447c54d99
Autor:
Joseph A. Perry, Lindsey Shallberg, Joseph T. Clark, Jodi A. Gullicksrud, Jonathan H. DeLong, Bonnie B. Douglas, Andrew P. Hart, Zachary Lanzar, Keenan O’Dea, Christoph Konradt, Jeongho Park, Juhi R. Kuchroo, Daniel Grubaugh, Arielle Glatman Zaretsky, Igor E. Brodsky, Rene de Waal Malefyt, David A. Christian, Arlene H. Sharpe, Christopher A. Hunter
Publikováno v:
Nature Immunology. 23:743-756
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1360105b00b4e769847c9bcbc34f3710
https://doi.org/10.1038/s41590-022-01170-w
https://doi.org/10.1038/s41590-022-01170-w
Autor:
Lindsey A. Shallberg, Jonathan H. DeLong, Glatman-Zaretzky A, Joseph T. Clark, de Waal Malefyt R, Douglas B, Jodi A. Gullicksrud, David A. Christian, Andrew P. Hart, Christopher A. Hunter, Park J, Christoph Konradt, Arlene H. Sharpe, Joseph A Perry
While much is known about the factors that promote the development of diverse Treg cell responses, less is known about the pathways that constrain Treg cell activities. The studies presented here reveal that at homeostasis there is a population of ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65feb5b6cb3e21905249e318fb7481ff
https://doi.org/10.1101/2020.12.09.416990
https://doi.org/10.1101/2020.12.09.416990
Autor:
Joseph A, Perry, Lindsey, Shallberg, Joseph T, Clark, Jodi A, Gullicksrud, Jonathan H, DeLong, Bonnie B, Douglas, Andrew P, Hart, Zachary, Lanzar, Keenan, O'Dea, Christoph, Konradt, Jeongho, Park, Juhi R, Kuchroo, Daniel, Grubaugh, Arielle Glatman, Zaretsky, Igor E, Brodsky, Rene de Waal, Malefyt, David A, Christian, Arlene H, Sharpe, Christopher A, Hunter
Publikováno v:
Nature immunology. 23(5)
Phenotypic and transcriptional profiling of regulatory T (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c134f7a5077759968ce6a774d788065e
https://pubmed.ncbi.nlm.nih.gov/35437326
https://pubmed.ncbi.nlm.nih.gov/35437326
Autor:
Marvin T. Nieman, Sidney W. Whiteheart, Shuchi Gupta, Jorge Di Paola, Christoph Konradt, Demin Wang, Adam Corken, Lawrence F. Brass, Bernhard Nieswandt, Jerry Ware, Mei Yu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 117(39)
Platelets are best known for their vasoprotective responses to injury and inflammation. Here, we have asked whether they also support vascular integrity when neither injury nor inflammation is present. Changes in vascular barrier function in dermal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758a62b775b07574c029319ec0a542e8
https://pubmed.ncbi.nlm.nih.gov/33595179
https://pubmed.ncbi.nlm.nih.gov/33595179
Publikováno v:
European Journal of Immunology. 48:1607-1620
There are over 10 trillion endothelial cells (EC) that line the vasculature of the human body. These cells not only have specialized functions in the maintenance of homeostasis within the circulation and various tissues but they also have a major rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3717d7ecded2afcfdc41f370dfd59afa
https://doi.org/10.1002/eji.201646789
https://doi.org/10.1002/eji.201646789
Autor:
Jeongho Park, Jonathan H. DeLong, Elia D. Tait Wojno, Christoph Konradt, James J. Knox, Christopher A. Hunter
Publikováno v:
Infect Immun
Interleukin-27 (IL-27) is a heterodimeric cytokine composed of the subunits IL-27p28 and EBi3, and while the IL-27 heterodimer influences T cell activities, there is evidence that IL-27p28 can have EBi3-independent activities; however, their relevanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c42edb83692be974af7c02b371f32d
https://doi.org/10.1128/iai.00455-19
https://doi.org/10.1128/iai.00455-19