Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Christoph J Binder"'
Autor:
Eva S Schernhammer, Christian Hengstenberg, Helmuth Haslacher, Thomas Perkmann, Tanja Stamm, Christian Nitsche, Christoph J Binder, Martin Riesenhuber, Friedrich Jakse, Elaaha Anwari, Fardin Hamidi, Thomas A Zelniker
Publikováno v:
BMJ Open, Vol 13, Iss 1 (2023)
Objectives This study aimed to estimate and compare the prevalence of the virus-specific antibodies against the SARS-CoV-2 nucleoprotein antigen (anti-SARS-CoV-2 N) in healthcare workers and an all-comer paediatric and adult patient population.Design
Externí odkaz:
https://doaj.org/article/cf0609ce421244e49b3069233d78303e
Autor:
Riem Gawish, Barbara Maier, Georg Obermayer, Martin L Watzenboeck, Anna-Dorothea Gorki, Federica Quattrone, Asma Farhat, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Arman Alimohammadi, Ildiko Mesteri, Felicitas Oberndorfer, Fiona Oakley, John Brain, Louis Boon, Irene Lang, Christoph J Binder, Sylvia Knapp
Publikováno v:
eLife, Vol 11 (2022)
Sepsis is a life-threatening condition characterized by uncontrolled systemic inflammation and coagulation, leading to multiorgan failure. Therapeutic options to prevent sepsis-associated immunopathology remain scarce. Here, we established a mouse mo
Externí odkaz:
https://doaj.org/article/488b92e3c6ae4a14a465997f8ae7c7c0
Autor:
Tim Hendrikx, Veerle Bieghs, Sofie M A Walenbergh, Patrick J van Gorp, Fons Verheyen, Mike L J Jeurissen, Mandy M F Steinbusch, Nathalie Vaes, Christoph J Binder, Ger H Koek, Rinke Stienstra, Mihai G Netea, Marten H Hofker, Ronit Shiri-Sverdlov
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e78792 (2013)
While non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis combined with inflammation, the mechanisms triggering hepatic inflammation are unknown. In Ldlr(-/-) mice, we have previously shown that lysosomal cholesterol accumulati
Externí odkaz:
https://doaj.org/article/359a9c9b1316462799400f896734f03a
Autor:
Xuchu Que, George F Widhopf, Shahzada Amir, Karsten Hartvigsen, Lotte F Hansen, Douglas Woelkers, Sotirios Tsimikas, Christoph J Binder, Thomas J Kipps, Joseph L Witztum
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65203 (2013)
The immunoglobulins expressed by chronic lymphocytic leukemia (CLL) B cells are highly restricted, suggesting they are selected for binding either self or foreign antigen. Of the immunoglobulin heavy-chain variable (IGHV) genes expressed in CLL, IGHV
Externí odkaz:
https://doaj.org/article/cc98243a866544aaaf1436e650601acd
Autor:
Dennis Wolf, Felix Jehle, Alexandra Ortiz Rodriguez, Bianca Dufner, Natalie Hoppe, Christian Colberg, Andrey Lozhkin, Nicole Bassler, Benjamin Rupprecht, Ansgar Wiedemann, Ingo Hilgendorf, Peter Stachon, Florian Willecke, Mark Febbraio, Constantin von zur Muhlen, Christoph J Binder, Christoph Bode, Andreas Zirlik, Karlheinz Peter
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33026 (2012)
BackgroundAdipose tissue inflammation fuels the metabolic syndrome. We recently reported that CD40L--an established marker and mediator of cardiovascular disease--induces inflammatory cytokine production in adipose cells in vitro. Here, we tested the
Externí odkaz:
https://doaj.org/article/f7d4422239554d5396a325a3d1078fdd
Autor:
Veerle Bieghs, Patrick J Van Gorp, Kristiaan Wouters, Tim Hendrikx, Marion J Gijbels, Marc van Bilsen, Jaap Bakker, Christoph J Binder, Dieter Lütjohann, Bart Staels, Marten H Hofker, Ronit Shiri-Sverdlov
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30668 (2012)
Non-alcoholic steatohepatitis (NASH) involves steatosis combined with inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular mechanisms of NASH is highly dependent on the availability of animal models. Currently, the mo
Externí odkaz:
https://doaj.org/article/7cba33b418da4a33825a3a3df69bae0b
Autor:
Veerle Bieghs, Fons Verheyen, Patrick J van Gorp, Tim Hendrikx, Kristiaan Wouters, Dieter Lütjohann, Marion J J Gijbels, Maria Febbraio, Christoph J Binder, Marten H Hofker, Ronit Shiri-Sverdlov
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34378 (2012)
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis and inflammation, which can further progress into fibrosis and cirrhosis. Recently, we demonstrated that combined deletion of the two main scavenger receptors, CD36 and macrophage sca
Externí odkaz:
https://doaj.org/article/fc66fc6496794096b9edf4dc02b0e037
This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume'Atherosclerosis: Diet and Drugs'reflects the state-of-the-art and most recent developments in at
Autor:
Tobias Niedrist, Lisa Kriegl, Christoph J. Zurl, Felix Schmidt, Nicole Perkmann-Nagele, Patrick Mucher, Manuela Repl, Ines Flieder, Astrid Radakovics, Daniela Sieghart, Helga Radner, Daniel Aletaha, Christoph J. Binder, Christian Gülly, Robert Krause, Markus Herrmann, Oswald F. Wagner, Thomas Perkmann, Helmuth Haslacher
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 61:332-338
Objectives Anti-nucleocapsid (NC) antibodies are produced in response to SARS-CoV-2 infection. Therefore, they are well suited for the detection of a previous infection. Especially in the case of seroprevalence studies or during the evaluation of a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0002aea7b3af8860ccf6652a3adbf82
https://doi.org/10.1515/cclm-2022-0875
https://doi.org/10.1515/cclm-2022-0875
Autor:
Tim Hendrikx, Florentina Porsch, Máté G. Kiss, Dragana Rajcic, Nikolina Papac-Miličević, Constanze Hoebinger, Laura Goederle, Anastasiya Hladik, Lisa E. Shaw, Hauke Horstmann, Sylvia Knapp, Sophia Derdak, Martin Bilban, Lena Heintz, Marcin Krawczyk, Rafael Paternostro, Michael Trauner, Matthias Farlik, Dennis Wolf, Christoph J. Binder
Publikováno v:
Journal of Hepatology, 77(5), 1373-1385. Elsevier Science
BACKGROUND & AIMS: Previous single-cell RNA-sequencing analyses have shown that Trem2-expressing macrophages are present in the liver during obesity, non-alcoholic steatohepatitis (NASH) and cirrhosis. Herein, we aimed to functionally characterize th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc35e9ab4202dfa69601804f0eecf88
https://doi.org/10.1016/j.jhep.2022.06.004
https://doi.org/10.1016/j.jhep.2022.06.004