Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Christoph H, Borchers"'
Publikováno v:
Journal of Mass Spectrometry. 56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::809960c54acc028225455537926c42fc
https://doi.org/10.1002/jms.4797
https://doi.org/10.1002/jms.4797
Autor:
Gaspar, Vanessa (AUTHOR), Ibrahim, Sahar (AUTHOR), Zahedi, René (AUTHOR), Borchers, Christoph (AUTHOR)
Publikováno v:
Journal of Mass Spectrometry. Nov2021, Vol. 56 Issue 11, p1-2. 2p.
Autor:
Darren M. Blackburn, Korin Sahinyan, Aldo Hernández-Corchado, Felicia Lazure, Vincent Richard, Laura Raco, Gabrielle Perron, René P. Zahedi, Christoph H. Borchers, Christoph Lepper, Hiroshi Kawabe, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110241- (2024)
Summary: Adult stem cells play a critical role in tissue repair and maintenance. In tissues with slow turnover, including skeletal muscle, these cells are maintained in a mitotically quiescent state yet remain poised to re-enter the cell cycle to rep
Externí odkaz:
https://doaj.org/article/aed6cff8a4964cb88e74903bb70434c9
Autor:
Sarah A. Michaud, Helena Pětrošová, Nicholas J. Sinclair, Andrea L. Kinnear, Angela M. Jackson, Jamie C. McGuire, Darryl B. Hardie, Pallab Bhowmick, Milan Ganguly, Ann M. Flenniken, Lauryl M. J. Nutter, Colin McKerlie, Derek Smith, Yassene Mohammed, David Schibli, Albert Sickmann, Christoph H. Borchers
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Mouse is the mammalian model of choice to study human health and disease due to its size, ease of breeding and the natural occurrence of conditions mimicking human pathology. Here we design and validate multiple reaction monitoring mass spec
Externí odkaz:
https://doaj.org/article/2609ea2007ea4af7ba418d2b5f7ec603
Autor:
Marisol Castillo-Castrejon, Barbara Mensah Sankofi, Stevi Johnson Murguia, Abasi-ama Udeme, Hoaning Howard Cen, Yi Han Xia, Nisha S. Thomas, William L. Berry, Kenneth L. Jones, Vincent R. Richard, Rene P. Zahedi, Christoph H. Borchers, James D. Johnson, Elizabeth A. Wellberg
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-21 (2023)
Abstract Background Obesity increases breast cancer risk and breast cancer-specific mortality, particularly for people with estrogen receptor (ER)-positive tumors. Body mass index (BMI) is used to define obesity, but it may not be the best predictor
Externí odkaz:
https://doaj.org/article/ddd8615423954129a10ae74ab8936c7b
Autor:
Constance A. Sobsey, Noor Mady, Vincent R. Richard, Andre LeBlanc, Thomas Zakharov, Christoph H. Borchers, R. Thomas Jagoe
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The cytochrome P450 enzyme subfamilies, including CYP3A4 and CYP1A2, have a major role in metabolism of a range of drugs including several anti-cancer treatments. Many factors including environmental exposures, diet, diseaserelated syst
Externí odkaz:
https://doaj.org/article/d4fe7fa4049f4675a002f17e3f4a7be1
Autor:
Veera Ganesh Yerra, Sri Nagarjun Batchu, Harmandeep Kaur, MD Golam Kabir, Youan Liu, Suzanne L. Advani, Duc Tin Tran, Shadi Sadeghian, Phelopater Sedrak, Filio Billia, Uros Kuzmanov, Anthony O. Gramolini, Deema O. Qasrawi, Evgeniy V. Petrotchenko, Christoph H. Borchers, Kim A. Connelly, Andrew Advani
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Inflammation promotes adverse ventricular remodeling, a common antecedent of heart failure. Here, we set out to determine how inflammatory cells affect cardiomyocytes in the remodeling heart. Pathogenic cardiac macrophages induced an IFN response in
Externí odkaz:
https://doaj.org/article/0c5911e4a2bf433aac0c14bc3122354f
Autor:
Onofrio Laselva, Evgeniy V. Petrotchenko, C. Michael Hamilton, Zafar Qureshi, Christoph H. Borchers, Robert N. Young, Christine E. Bear
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101258- (2022)
Summary: We describe a protocol to identify the binding site(s) for a drug called ivacaftor that potentiates the CFTR chloride channel. We use photoaffinity probes—based on the structure of ivacaftor—to covalently modify the CFTR protein at the r
Externí odkaz:
https://doaj.org/article/d780e2dbabf949ef8626b66fff79d3bc
Autor:
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
Abstract We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our
Externí odkaz:
https://doaj.org/article/72bd932c9079468a9baf2be34f40d25f
Autor:
Marco De Giorgi, Kelsey E. Jarrett, Jason C. Burton, Alexandria M. Doerfler, Ayrea Hurley, Ang Li, Rachel H. Hsu, Mia Furgurson, Kalyani R. Patel, Jun Han, Christoph H. Borchers, William R. Lagor
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1675-1686 (2020)
HMG-CoA reductase (Hmgcr) is the rate-limiting enzyme in the mevalonate pathway and is inhibited by statins. In addition to cholesterol, Hmgcr activity is also required for synthesizing nonsterol isoprenoids, such as dolichol, ubiquinone, and farnesy
Externí odkaz:
https://doaj.org/article/ed795593e77944b1aba45644fccaf0d5