Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Christoph Giese"'
The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili
Autor:
Dawid S. Zyla, Thomas Wiegand, Paul Bachmann, Rafal Zdanowicz, Christoph Giese, Beat H. Meier, Gabriel Waksman, Manuela K. Hospenthal, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Type 1 pili are important virulence factors of uropathogenic Escherichia coli that mediate bacterial attachment to epithelial cells in the urinary tract. The pilus rod is comprised of thousands of copies of the main structural subunit FimA a
Externí odkaz:
https://doaj.org/article/884d08eb71b24e7aa30ce532b269e3b7
Autor:
Christoph Giese, Chasper Puorger, Oleksandr Ignatov, Zuzana Bečárová, Marco E. Weber, Martin A. Schärer, Guido Capitani, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Adhesive type 1 pili from uropathogenic Escherichia coli strains are filamentous, supramolecular protein complexes consisting of a short tip fibrillum and a long, helical rod formed by up to several thousand copies of the major pilus subunit
Externí odkaz:
https://doaj.org/article/d39c9c2a626e485287cd4ec9a1f3df84
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Mycobacteria evade the toxic effects of Cyclomarin A (CymA) by massive autoupregulated expression of the partial ClpC1 homologue ClpC2 that thereby acts as a tightly binding molecular sponge to prevent CymA binding to ClpCP.
Externí odkaz:
https://doaj.org/article/7911fc46eedd40ea9a0f0c4408b18901
Autor:
Michal Ziemski, Ahmad Jomaa, Daniel Mayer, Sonja Rutz, Christoph Giese, Dmitry Veprintsev, Eilika Weber-Ban
Publikováno v:
eLife, Vol 7 (2018)
Cdc48 is a AAA+ ATPase that plays an essential role for many cellular processes in eukaryotic cells. An archaeal homologue of this highly conserved enzyme was shown to directly interact with the 20S proteasome. Here, we analyze the occurrence and phy
Externí odkaz:
https://doaj.org/article/a4505d885d54412a852a61e58252c44d
Autor:
Julia Rosenlöcher, Verena Böhrsch, Michael Sacharjat, Véronique Blanchard, Christoph Giese, Volker Sandig, Christian P. R. Hackenberger, Stephan Hinderlich
Publikováno v:
Bioengineering, Vol 2, Iss 4, Pp 213-234 (2015)
Manipulations of cell surface glycosylation or glycan decoration of selected proteins hold immense potential for exploring structure-activity relations or increasing glycoprotein quality. Metabolic glycoengineering describes the strategy where exogen
Externí odkaz:
https://doaj.org/article/b876e37c4dee42e2967b6abfacb50ab4
Autor:
Lars Radke, Grit Sandig, Annika Lubitz, Ulrike Schließer, Hans Henning von Horsten, Veronique Blanchard, Karolin Keil, Volker Sandig, Christoph Giese, Michael Hummel, Stephan Hinderlich, Marcus Frohme
Publikováno v:
Bioengineering, Vol 4, Iss 3, p 70 (2017)
Subunit vaccines often require adjuvants to elicit sustained immune activity. Here, a method is described to evaluate the efficacy of single vaccine candidates in the preclinical stage based on cytokine and gene expression analysis. As a model, the r
Externí odkaz:
https://doaj.org/article/730c6522236b4899bd9ecba2c1da964e
Autor:
Sirine Nouri, Julien Boudet, Hiang Dreher-Teo, Frédéric H.-T. Allain, Rudi Glockshuber, Loïc Salmon, Christoph Giese
Publikováno v:
Angewandte Chemie. International Edition
In NMR spectroscopy, residual dipolar couplings (RDCs) have emerged as one of the most exquisite probes of biological structure and dynamics. The measurement of RDCs relies on the partial alignment of the molecule of interest, for example by using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeffd38df3ea733f7a417c39ca507a7
https://doi.org/10.1002/anie.202305120
https://doi.org/10.1002/anie.202305120
Autor:
Christoph Giese, Chasper Puorger, Oleksandr Ignatov, Zuzana Bečárová, Marco E. Weber, Martin A. Schärer, Guido Capitani, Rudi Glockshuber
SUMMARYAdhesive type 1 pili from uropathogenicEscherichia colistrains are filamentous, supramolecular protein complexes consisting of a short tip fibrillum and a long, helical rod formed by up to several thousand copies of the major pilus subunit Fim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b6fd2b939e902852fb3b8f7e80e98c
https://doi.org/10.1101/2022.10.11.511808
https://doi.org/10.1101/2022.10.11.511808
Autor:
Christoph Giese, Jochen Zahn
Publikováno v:
Physical Review D. 106
We study the dynamics of charged, spherically symmetric dust shells in the presence of a positive cosmological constant. We find generalizations of the well-known solutions in asymptotically flat spacetime, in particular orbits into "parallel univers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a5ef57a6bf673959f02f6b63c6aee1
https://doi.org/10.1103/physrevd.106.064005
https://doi.org/10.1103/physrevd.106.064005
Autor:
R. Gregor Weiß, Christoph Giese, Markus Aebi, Sereina Riniker, Marie-Estelle Losfeld, Corina Mathew, Rudi Glockshuber, Chia-Wei Lin
Publikováno v:
RSC Chemical Biology. 2:917-931
A hallmark of N-linked glycosylation in the secretory compartments of eukaryotic cells is the sequential remodeling of an initially uniform oligosaccharide to a site-specific, heterogeneous ensemble of glycostructures on mature proteins. To understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49c01eaebf3a3bcd085880f052f7ed94
https://doi.org/10.1039/d1cb00019e
https://doi.org/10.1039/d1cb00019e