Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christoph G Gäbelein"'
Autor:
Chantal Ernst, Patrick R Andreassen, Gabriel H Giger, Bidong D Nguyen, Christoph G Gäbelein, Orane Guillaume-Gentil, Stefan A Fattinger, Mikael E Sellin, Wolf-Dietrich Hardt, Julia A Vorholt
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002597 (2024)
Intestinal epithelial cells (IECs) play pivotal roles in nutrient uptake and in the protection against gut microorganisms. However, certain enteric pathogens, such as Salmonella enterica serovar Typhimurium (S. Tm), can invade IECs by employing flage
Externí odkaz:
https://doaj.org/article/be0194b104fc4fb58354f7d0ece570b5
Autor:
Christoph G Gäbelein, Qian Feng, Edin Sarajlic, Tomaso Zambelli, Orane Guillaume-Gentil, Benoît Kornmann, Julia A Vorholt
Publikováno v:
PLoS Biology, Vol 20, Iss 3, p e3001576 (2022)
Mitochondria and the complex endomembrane system are hallmarks of eukaryotic cells. To date, it has been difficult to manipulate organelle structures within single live cells. We developed a FluidFM-based approach to extract, inject, and transplant o
Externí odkaz:
https://doaj.org/article/1a1a01f6939344d3bba7c6ce9f3308fe
Autor:
Orane Guillaume-Gentil, Christoph G. Gäbelein, Stefanie Schmieder, Vincent Martinez, Tomaso Zambelli, Markus Künzler, Julia A. Vorholt
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Guillaume-Gentil et al. describe a method that employs a modified AFM tip for selectively sampling from and injecting into individual fungal cells of differing morphology. The authors describe extensive modifications on their system previously used f
Externí odkaz:
https://doaj.org/article/bac24386c73744bb851a80760246103c
Autor:
Sebastian Pfeilmeier, Anja Werz, Marine Ote, Miriam Bortfeld-Miller, Pascal Kirner, Andreas Keppler, Lucas Hemmerle, Christoph G. Gäbelein, Christine M. Pestalozzi, Julia A. Vorholt
Dysbiosis is characterized by a perturbed microbiota associated with host disease. In both plants and animals, the innate immune system contributes to maintain microbiota homeostasis in healthy organisms, with NADPH oxidases playing a crucial role. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50cb1b7cae0ba29aa7e7bef58c272df
https://doi.org/10.1101/2023.05.09.539948
https://doi.org/10.1101/2023.05.09.539948
Publikováno v:
ACS synthetic biology. 11(10)
Endosymbioses are cellular mergers in which one cell lives within another cell and have led to major evolutionary transitions, most prominently to eukaryogenesis. Generation of synthetic endosymbioses aims to provide a defined starting point for stud
Autor:
Lucas Hemmerle, Benjamin A. Maier, Miriam Bortfeld-Miller, Birgitta Ryback, Christoph G. Gäbelein, Martin Ackermann, Julia A. Vorholt
Publikováno v:
Nature Communications, 13 (1)
Differences between species promote stable coexistence in a resource-limited environment. These differences can result from interspecies competition leading to character shifts, a process referred to as character displacement. While character displac
Autor:
Wanze Chen, Orane Guillaume-Gentil, Pernille Yde Rainer, Christoph G. Gäbelein, Wouter Saelens, Vincent Gardeux, Amanda Klaeger, Riccardo Dainese, Magda Zachara, Tomaso Zambelli, Julia A. Vorholt, Bart Deplancke
Publikováno v:
Nature, 608 (7924)
Nature
Nature
Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize cellular heterogeneity. However, scRNA-seq requires lysing cells, which impedes further molecular or functional analyses on the same cells. Here, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fc08083d617e215e7fa59016f248bf
Autor:
Matthias Meier, Nicolas Gobet, Tihomir Georgiev, Christoph G Gäbelein, Wilfried Weber, Nils Schneider, Julius Wiener
Publikováno v:
ACS chemical biology. 13(11)
We here present a method that combines genetic code expansion with CRISPR/Cas9 genome engineering to label endogenously expressed proteins with high spatiotemporal resolution. The method exploits the use of an orthogonal tRNA/tRNA synthetase pair in
Autor:
Anne Müller, Philipp M Warmer, Fenja Gawlas, Philipp Schwenk, Michael Agne, Alica J. Emhardt, Lisa J Schmunk, Manuel C. Scheidmann, Gerald Radziwill, Thomas J Juretschke, Patrick Gonschorek, Maximilian R Stammnitz, Stefan D Krämer, Beate Kaufmann, Lisa M Schäfer, Nadine Gillich, Ilona Blank, Alina Rudorf, Natalie Louis, Christoph G Gäbelein, Wilfried Weber, Adrian Fischer, Hanna J. Wagner
Publikováno v:
ACS Synthetic Biology. 3:986-989
The ability to control mammalian genes in a synergistic mode using synthetic transcription factors is highly desirable in fields of tissue engineering, stem cell reprogramming and fundamental research. In this study, we developed a standardized toolk
Autor:
'Christoph G. Gäbelein
Publikováno v:
Qian Feng