Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Christoph F. Kurat"'
Autor:
Priyanka Bansal, Christoph F. Kurat
Publikováno v:
Molecular & Cellular Oncology, Vol 9, Iss 1 (2022)
We have recently revealed the existence of a cell cycle-regulated chromatin segregase, Yta7 (Yeast Tat-binding Analog 7), involved in chromosome replication. Phosphorylation of Yta7 by S-CDK (S-phase Cyclin-Dependent Kinase) regulates its function. T
Externí odkaz:
https://doaj.org/article/96e497f55f7447088456337fe615c16a
Autor:
Erika Chacin, Priyanka Bansal, Karl-Uwe Reusswig, Luis M. Diaz-Santin, Pedro Ortega, Petra Vizjak, Belen Gómez-González, Felix Müller-Planitz, Andrés Aguilera, Boris Pfander, Alan C. M. Cheung, Christoph F. Kurat
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
How cells coordinate chromatin dynamics with the cell cycle machinery to promote genome duplication during S phase is still a matter of study. Here the authors reveal by in vitro reconstitution assays that the AAA + -ATPase containing Yta7 protein in
Externí odkaz:
https://doaj.org/article/77718c498bfb45589d2351c40e0546be
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 6, Pp 1993-2006 (2018)
The Hif1 protein in the yeast Saccharomyces cerevisie is an evolutionarily conserved H3/H4-specific chaperone and a subunit of the nuclear Hat1 complex that catalyzes the acetylation of newly synthesized histone H4. Hif1, as well as its human homolog
Externí odkaz:
https://doaj.org/article/9f316cfcbfa944e9908efc9e949c324a
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011366 (2024)
In Saccharomyces cerevisiae, the forkhead (Fkh) transcription factor Fkh1 (forkhead homolog) enhances the activity of many DNA replication origins that act in early S-phase (early origins). Current models posit that Fkh1 acts directly to promote thes
Externí odkaz:
https://doaj.org/article/2360b81529ef4b71ad7488bf4d73cdf6
Autor:
Erika Chacin, Karl-Uwe Reusswig, Jessica Furtmeier, Priyanka Bansal, Leonhard A. Karl, Boris Pfander, Tobias Straub, Philipp Korber, Christoph F. Kurat
Publikováno v:
Nature. 616:836-842
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90f8cd8d6bb0d68fa5bbcc46dc26473
https://doi.org/10.1038/s41586-023-05926-8
https://doi.org/10.1038/s41586-023-05926-8
Autor:
Barbara Safaric, Erika Chacin, Matthias J Scherr, Lional Rajappa, Christian Gebhardt, Christoph F Kurat, Thorben Cordes, Karl E Duderstadt
Publikováno v:
Nucleic Acids Research
Chromosome replication depends on efficient removal of nucleosomes by accessory factors to ensure rapid access to genomic information. Here, we show this process requires recruitment of the nucleosome reorganization activity of the histone chaperone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d533d27c64a9ba91023903331dd2a6e5
https://doi.org/10.1093/nar/gkac005
https://doi.org/10.1093/nar/gkac005
Autor:
Boris Pfander, Petra Vizjak, Belén Gómez-González, Christoph F. Kurat, Alan C. M. Cheung, E. Chacin, P. Bansal, Karl-Uwe Reusswig, Felix Mueller-Planitz, Luis Miguel Díaz-Santín, Andrés Aguilera, Pedro A. Ortega
The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can result in genome instability, which is a major driver of cancer. Yet how chromatin is made accessible during eukaryotic DNA synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a911f15a9c192501096da40a47cb08d4
https://doi.org/10.1101/2020.11.20.390914
https://doi.org/10.1101/2020.11.20.390914
Autor:
Sevil Zencir, Anne-Marinette Cao, Ruud Hovius, Beat Fierz, David Shore, Christoph F. Kurat, Anna Maria Stachowicz, Maxime Mivelaz, Slawomir Kubik, Iuliia Boichenko
Pioneer transcription factors (pTFs) bind to target sites within compact chromatin initiating chromatin remodeling and controlling the recruitment of downstream factors. The mechanisms by which pTFs overcome the chromatin barrier are not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7adc84c11d74b77c418b2b5e6128626
Publikováno v:
Molecular Cell
Summary The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still poorly understood. Using purified yeast replication proteins and fully chromatinized templates, we have reconstituted th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310f2353d734965409ab19de0c9a8ede
Autor:
Igor Jurisica, Christoph F. Kurat, Julia Petschnigg, Susan Lindquist, Jason Moffat, Mikko Taipale, Bella Groisman, Tony Pawson, Igor Stagljar, Ming-Sound Tsao, Alex Nachman, Mojca Mattiazzi Usaj, Max Kotlyar, Jamie Snider, Irina Krykbaeva, Azin Sayad, Yong Zheng, J Rafael Sierra
Publikováno v:
Nature Methods. 11:585-592
A method based on the split-ubiquitin assay monitors interactions between membrane proteins within human cells. Cell signaling, one of key processes in both normal cellular function and disease, is coordinated by numerous interactions between membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf572acdea99046e5248e74d74b6360
https://doi.org/10.1038/nmeth.2895
https://doi.org/10.1038/nmeth.2895