Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Christoph Denk"'
Autor:
Daniel Lumpi, Hannes Mikula, Christoph Denk, Günter Allmaier, Christian Hametner, Dennis Svatunek, Gottfried Eilenberger
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
The strain‐promoted azide alkyne cycloaddition (SPAAC) is a powerful tool for forming covalent bonds between molecules even under physiological conditions, and therefore found broad application in fields ranging from biological chemistry and biomed
Autor:
Johannes Burkard, Lucas Kohler, Sophia Caciagli, Nicolas Herren, Mark Kozamernik, Saskia Mantovani, Erich J. Windhab, Christoph Denkel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In view of the health concerns associated with high sugar intake, this study investigates methods to enhance sweetness perception in chocolate without increasing its sugar content. Using additive manufacturing, chocolate structures were crea
Externí odkaz:
https://doaj.org/article/3b217070e96c44c891402d4c3c60c054
Autor:
Christoph Denk, Martin Wilkovitsch, Melanie Maurer, Thomas Wanek, Hannes Mikula, Severin Mairinger, Veronika Rosecker
Publikováno v:
Chembiochem
ChemBioChem
ChemBioChem
Radiotheranostics are designed by labeling targeting (bio)molecules with radionuclides for diagnostic or therapeutic application. Because the pharmacokinetics of therapeutic compounds play a pivotal role, chemically closely related imaging agents are
Autor:
Matthias M. Herth, Martin Wilkovitsch, Sture Lindegren, Emma Aneheim, Christoph Denk, Hannes Mikula, Holger Jensen
Publikováno v:
Chempluschem
ChemPlusChem
Denk, C, Wilkovitsch, M, Aneheim, E, Herth, M M, Jensen, H, Lindegren, S & Mikula, H 2019, ' Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio-Crosslinking ', ChemPlusChem, vol. 219, no. 84, pp. 775-778 . https://doi.org/10.1002/cplu.201900114
ChemPlusChem
Denk, C, Wilkovitsch, M, Aneheim, E, Herth, M M, Jensen, H, Lindegren, S & Mikula, H 2019, ' Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio-Crosslinking ', ChemPlusChem, vol. 219, no. 84, pp. 775-778 . https://doi.org/10.1002/cplu.201900114
In the past decade, several developments have expanded the chemical toolbox for astatination and the preparation of 211At‐labeled radiopharmaceuticals. However, there is still a need for advanced methods for the synthesis of astatinated (bio)molecu
Autor:
Matthias M. Herth, Christoph Denk, E. Johanna L. Stéen, Vladimir Shalgunov, Andreas Kjaer, Hannes Mikula, Jesper L. Kristensen
Publikováno v:
European Journal of Organic Chemistry. 2019:1722-1725
Fluorine-18 possesses outstanding decay characteristics for positron emission tomography (PET) imaging. Therefore, it is ideally suited for clinical applications. As such, improved strategies to incorporate fluorine-18 into bioactive molecules are of
Autor:
Kelsey A. Stoerzinger, Eszter Baráth, Yue Liu, Johannes A. Lercher, Libor Kovarik, Sebastian Foraita, Christoph Denk
Publikováno v:
Catalysis Science & Technology. 9:2620-2629
Hydrodeoxygenation of stearic acid on Ni/ZrO2 to n-heptadecane occurs via the reduction to 1-octadecanal, followed by decarbonylation of the aldehyde to n-heptadecane. Stearic acid binds stronger than 1-octadecanal on Ni, causing decarbonylation to s
Autor:
Lisa I. Wadiura, Ludwig Pichler, Matthias Millesi, Julius Lukas, Christian Matula, Christoph Denk
Publikováno v:
World neurosurgery. 153
Background Cavernous venous malformations (CVMs) represent the most common benign intraorbital lesions. Enlarging or symptomatic CVMs (progressive proptosis or visual disturbances) are treated by surgical resection. For this, a variety of different s
Autor:
E Johanna L, Stéen, Jesper T, Jørgensen, Christoph, Denk, Umberto M, Battisti, Kamilla, Nørregaard, Patricia E, Edem, Klas, Bratteby, Vladimir, Shalgunov, Martin, Wilkovitsch, Dennis, Svatunek, Christian B M, Poulie, Lars, Hvass, Marina, Simón, Thomas, Wanek, Raffaella, Rossin, Marc, Robillard, Jesper L, Kristensen, Hannes, Mikula, Andreas, Kjaer, Matthias M, Herth
Publikováno v:
ACS pharmacologytranslational science. 4(2)
The development of highly selective and fast biocompatible reactions for ligation and cleavage has paved the way for new diagnostic and therapeutic applications of pretargeted
Publikováno v:
Synlett. 29:1297-1302
The fast and biocompatible ligation of 1,2,4,5-tetrazines with strained alkenes has found numerous applications in biomedical sciences. The reactivity of a 1,2,4,5-tetrazine can generally be tuned by changing its electronic properties by varying the
Publikováno v:
Monatshefte für Chemie-Chemical Monthly
Monatshefte Fur Chemie
Monatshefte Fur Chemie
The tetrazine ligation is one of the fastest bioorthogonal ligations and plays a pivotal role in time-critical in vitro and in vivo applications. However, prediction of the reactivity of tetrazines in inverse electron demand Diels–Alder-initiated l