Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Christoph A. Wehe"'
Autor:
Anna Hucke, Marta Kantauskaite, Tim N. Köpp, Christoph A. Wehe, Uwe Karst, Pavel I. Nedvetsky, Giuliano Ciarimboli
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2922 (2024)
Cisplatin (CDDP) stands out as an effective chemotherapeutic agent; however, its application is linked to the development of significant adverse effects, notably nephro- and ototoxicity. The human organic cation transporter 2 (hOCT2), found in abunda
Externí odkaz:
https://doaj.org/article/7447d84224eb4bffac0af066a02b9b63
Autor:
Anna Hucke, Ga Young Park, Oliver B. Bauer, Georg Beyer, Christina Köppen, Dorothea Zeeh, Christoph A. Wehe, Michael Sperling, Rita Schröter, Marta Kantauskaitè, Yohannes Hagos, Uwe Karst, Stephen J. Lippard, Giuliano Ciarimboli
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Cancer treatment with platinum compounds is an important achievement of modern chemotherapy. However, despite the beneficial effects, the clinical impact of these agents is hampered by the development of drug resistance as well as dose-limiting side
Externí odkaz:
https://doaj.org/article/a08b11d276134b76b82f7a8c9f729f2d
Autor:
Christoph A. Wehe, Olga Reifschneider, Katia Garbert, Maximilian von Bremen-Kühne, Sigrid Richter-Brockmann, Uwe Karst, Jörg Kudla, Ina Schmitz-Thom, Lukas Wallrad, Michael R. Sperling
Publikováno v:
Journal of Analytical Atomic Spectrometry. 35:2057-2063
Increasing soil salinity is a major problem in global crop production. The detrimental effect of saline soils on plant growth results from ionic toxicity of the Na+ ion in combination with osmotic perturbation. However, the mechanisms of Na uptake in
Publikováno v:
Journal of Chromatography A. 1440:105-111
In recent decades, a significant amount of anthropogenic gadolinium has been released into the environment as a result of the broad application of contrast agents for magnetic resonance imaging (MRI). Since this anthropogenic gadolinium anomaly has a
Publikováno v:
Metallomics. 8:101-107
The interaction of mercury species with human erythrocytes is studied to investigate possible high molecular binding partners for mercury species. Human blood hemolysate was spiked with methylmercury and investigated by means of liquid chromatography
Publikováno v:
Journal of Chromatography A. 1419:81-88
Thyroxine (T4) is one of the major thyroid hormones, which regulates cellular metabolism, central nervous system development, body temperature, reproduction and growth. The simulation of oxidation reactions of T4 may provide further information about
Autor:
Marvin Birka, Uwe Karst, Christoph A. Wehe, Rudolf Stadler, Elke Lusmöller, Michael R. Sperling, Kristina S. Wentker, Brigit Arheilger
Publikováno v:
Analytical Chemistry. 87:3321-3328
The combined use of elemental bioimaging and speciation analysis is presented as a novel means for the diagnosis of nephrogenic systemic fibrosis (NSF), a rare disease occurring after administration of gadolinium-based contrast agents (GBCA) for magn
Autor:
Christoph A. Wehe, Sandra Stoeppeler, Steffen Höll, Gregor Hauschild, Jendrik Hardes, Helmut Ahrens, Franziska Blaske, Uwe Karst, Georg Gosheger
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Infection associated with biomaterials used for orthopedic prostheses remains a serious complication in orthopedics, especially tumor surgery. Silver-coating of orthopedic (mega)prostheses proved its efficiency in reducing infections but has been lim
Autor:
A. von Schaewen, Michael R. Sperling, Georgina M. Thyssen, Heidi Kaulfürst-Soboll, Michael Holtkamp, Christoph A. Wehe, Uwe Karst
Publikováno v:
Metallomics : integrated biometal science. 9(6)
Laser ablation-inductively coupled plasma-optical emission spectroscopy (LA-ICP-OES) is presented as a valuable tool for elemental bioimaging of alkali and earth alkali elements in plants. Whereas LA-ICP-OES is commonly used for micro analysis of sol
Publikováno v:
Rapid Communications in Mass Spectrometry. 28:2627-2635
RATIONALE Two different approaches to improve the limits of detection (LODs) in elemental bioimaging have been developed. They both consider the fact that for the widely applied quadrupole-based instruments, metals in the mass range