Zobrazeno 1 - 10
of 585
pro vyhledávání: '"Christoph A. Weber"'
Autor:
Sudarshana Laha, Jonathan Bauermann, Frank Jülicher, Thomas C. T. Michaels, Christoph A. Weber
Publikováno v:
Physical Review Research, Vol 6, Iss 4, p 043092 (2024)
Phase-separated liquid condensates can spatially organize and thereby regulate chemical processes. However, the physicochemical mechanisms underlying such regulation remain elusive as the intramolecular interactions responsible for phase separation g
Externí odkaz:
https://doaj.org/article/68ef165094d149bf8f4c9c8e87f1588d
Autor:
Alexander M. Bergmann, Jonathan Bauermann, Giacomo Bartolucci, Carsten Donau, Michele Stasi, Anna-Lena Holtmannspötter, Frank Jülicher, Christoph A. Weber, Job Boekhoven
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Liquid-liquid phase separation yields spherical droplets that eventually coarsen to one large, stable droplet governed by the principle of minimal free energy. In chemically fueled phase separation, the formation of phase-separating molecule
Externí odkaz:
https://doaj.org/article/dafaece742364346811d5aa54af5f4a6
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033138 (2024)
We present a theory for phase-separated liquid coacervates with salt, taking into account spatial heterogeneities and interfacial profiles. We find that charged layers of alternating sign can form around the interface while the bulk phases remain app
Externí odkaz:
https://doaj.org/article/f1ba357d83a840d7a95457b617da64bc
Publikováno v:
Physical Review Research, Vol 5, Iss 4, p 043246 (2023)
We study a chemically active binary mixture undergoing phase separation and show that under nonequilibrium conditions, stable liquid spherical shells can form via a spinodal instability in the droplet center. A single liquid shell tends to grow until
Externí odkaz:
https://doaj.org/article/a60904a5ca8c405a848f70e8deaa9857
Publikováno v:
Physical Review Research, Vol 4, Iss 4, p 043173 (2022)
Liquid condensates are membraneless organelles that form via phase separation in living cells. These condensates provide unique heterogeneous environments that have much potential in regulating a range of biochemical processes from gene expression to
Externí odkaz:
https://doaj.org/article/ce83cd98e8214159be5f56e527912a8e
Publikováno v:
Physical Review Research, Vol 3, Iss 4, p 043150 (2021)
We discuss the stochastic trajectories of single molecules in a phase-separated liquid, when a dense and a dilute phase coexist. Starting from a continuum theory of macroscopic phase separation we derive a stochastic Langevin equation for molecular t
Externí odkaz:
https://doaj.org/article/2009edd7ce4c4e2c850d3a83dcc2211d
Publikováno v:
Physical Review X, Vol 4, Iss 4, p 041030 (2014)
Kinetic theories constitute one of the most promising tools to decipher the characteristic spatiotemporal dynamics in systems of actively propelled particles. In this context, the Boltzmann equation plays a pivotal role, since it provides a natural t
Externí odkaz:
https://doaj.org/article/629582c4f94f481db74b817b36c79392
Autor:
Lars Hubatsch, Louise M Jawerth, Celina Love, Jonathan Bauermann, TY Dora Tang, Stefano Bo, Anthony A Hyman, Christoph A Weber
Publikováno v:
eLife, Vol 10 (2021)
Key processes of biological condensates are diffusion and material exchange with their environment. Experimentally, diffusive dynamics are typically probed via fluorescent labels. However, to date, a physics-based, quantitative framework for the dyna
Externí odkaz:
https://doaj.org/article/eb40ee1913f644cab05a643ca5e29dae
Publikováno v:
Physical Review E
Chemically active systems such as living cells are maintained out of thermal equilibrium due to chemical events which generate heat and lead to active fluctuations. A key question is to understand on which time and length scales active fluctuations d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3831e68989e3a5aa4d919b9f0161e5
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/103936
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/103936
Interactions among proteins in living cells can lead to molecular assemblies of different sizes and large-scale coexisting phases formed via phase separation. Both are essential for the spatial organization of cells and for regulating biological func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4c20b5a00778e152d9fab54213a72b
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/104169
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/104169