Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Christoph A Schatz"'
Autor:
Pascale Lejeune, Véronique Cruciani, Axel Berg-Larsen, Andreas Schlicker, Anne Mobergslien, Lisa Bartnitzky, Sandra Berndt, Sabine Zitzmann-Kolbe, Claudia Kamfenkel, Stefan Stargard, Stefanie Hammer, Jennifer S Jørgensen, Malene Jackerott, Carsten H Nielsen, Christoph A Schatz, Hartwig Hennekes, Jenny Karlsson, Alan S Cuthbertson, Dominik Mumberg, Urs B Hagemann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/05e7344e8ce54a129a43af0ebbd6ec6f
Autor:
Jenny Karlsson, Christoph A. Schatz, Antje M. Wengner, Stefanie Hammer, Arne Scholz, Alan Cuthbertson, Volker Wagner, Hartwig Hennekes, Vicki Jardine, Urs B. Hagemann
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
Targeted alpha therapy (TAT) is a promising approach for addressing unmet needs in oncology. Inherent properties make α-emitting radionuclides well suited to cancer therapy, including high linear energy transfer (LET), penetration range of 2–10 ce
Externí odkaz:
https://doaj.org/article/79d527281ca44a4b9b38e38914580781
Autor:
Cuthbertson, Jenny Karlsson, Urs B. Hagemann, Véronique Cruciani, Christoph A. Schatz, Derek Grant, Christine Ellingsen, Alexander Kristian, Shirin Katoozi, Dessislava Mihaylova, Steinar R. Uran, Mari Suominen, Roger M. Bjerke, Olav B. Ryan, Alan
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3419
Human epidermal growth factor receptor 2 (HER2) is overexpressed in 15–30% of breast cancers but has low expression in normal tissue, making it attractive for targeted alpha therapy (TAT). HER2-positive breast cancer typically metastasizes to bone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::01b517f723aec72104e841d479d4b16e
Autor:
Paul P. Tamburini, Gerald Ranges, Andrei Voznesensky, Yong S. Chang, Sha Ha, Pamela Trail, Timothy J. McCabe, Lila Adnane, Charlotte C. Kopitz, Christoph A. Schatz, Heike M. Petrul
PDF file - 79K, Targeted tubulin disruption by BAY 79-4620.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198e42f70f285057e96625123d16da4f
https://doi.org/10.1158/1535-7163.22498530.v1
https://doi.org/10.1158/1535-7163.22498530.v1
Autor:
Karl Ziegelbauer, Dominik Mumberg, William J. Scott, Scott M. Wilhelm, Martin Hentemann, Dean P. Wilkie, Paul R. Fracasso, Christoph A. Schatz, Andrea Haegebarth, Claudia Schneider, Cathy O. Bull, Bruce R. Rowley, Ningshu Liu
Supplementary Materials and Methods. Supplemental Table S1. Combination effects of BAY 80-6946 and lapatinib on caspase 9 activation in BT474 cells. Supplemental Table S2. Single dose i.v. pharmacokinetic parameter of BAY 80-6946 in female nude rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1474ccb7f22408bd87b65c4e0d64c418
https://doi.org/10.1158/1535-7163.22498903.v1
https://doi.org/10.1158/1535-7163.22498903.v1
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
PDF - 118K, Supplementary Table S1. Mesothelin staining intensity in FFPE tissues of human primary ovarian cancer, pancreatic cancer and mesothelioma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851a39590f944f943652dd8cf92bb67
https://doi.org/10.1158/1535-7163.22499859
https://doi.org/10.1158/1535-7163.22499859
Autor:
Dominik Mumberg, Karl Ziegelbauer, Michael Brands, Franz von Nussbaum, Andreas Schlicker, Pascale Lejeune, Bernard Haendler, Simon J. Baumgart, Christoph A. Schatz, Sven Golfier, Uwe Eberspächer, Dieter Moosmayer, Ulf Bömer, Benjamin Bader, Philip Lienau, Lars Wortmann, Julien Lefranc, Ulrich Lücking, Gerhard Siemeister, Antje M. Wengner
Detailed method descriptions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b320e3c23f072f7d98b788ef8e1aa81
https://doi.org/10.1158/1535-7163.22507162
https://doi.org/10.1158/1535-7163.22507162
Autor:
Paul P. Tamburini, Gerald Ranges, Andrei Voznesensky, Yong S. Chang, Sha Ha, Pamela Trail, Timothy J. McCabe, Lila Adnane, Charlotte C. Kopitz, Christoph A. Schatz, Heike M. Petrul
PDF file - 82K, Anti-CAIX Western blot of tumor lysates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41582bbaa28091a254819138359c865c
https://doi.org/10.1158/1535-7163.22498542
https://doi.org/10.1158/1535-7163.22498542
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
Mesothelin is a tumor differentiation antigen frequently overexpressed in tumors such as mesothelioma, ovarian, pancreatic, and lung adenocarcinomas while showing limited expression in nonmalignant tissues. Mesothelin is therefore an attractive targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95b089c26fcbc4b0cf108dc63a5d571f
https://doi.org/10.1158/1535-7163.c.6536289
https://doi.org/10.1158/1535-7163.c.6536289
Autor:
Dominik Mumberg, Karl Ziegelbauer, Michael Brands, Franz von Nussbaum, Andreas Schlicker, Pascale Lejeune, Bernard Haendler, Simon J. Baumgart, Christoph A. Schatz, Sven Golfier, Uwe Eberspächer, Dieter Moosmayer, Ulf Bömer, Benjamin Bader, Philip Lienau, Lars Wortmann, Julien Lefranc, Ulrich Lücking, Gerhard Siemeister, Antje M. Wengner
The DNA damage response (DDR) secures the integrity of the genome of eukaryotic cells. DDR deficiencies can promote tumorigenesis but concurrently may increase dependence on alternative repair pathways. The ataxia telangiectasia and Rad3-related (ATR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71b4129b5b767f4375ccfbccdc80fc9
https://doi.org/10.1158/1535-7163.c.6538606.v1
https://doi.org/10.1158/1535-7163.c.6538606.v1