Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Christoph A Reichel"'
Autor:
Bernd Uhl, Laura AMittmann, Julian Dominik, Roman Hennel, Bojan Smiljanov, Florian Haring, Johanna BSchaubächer, Constanze Braun, Lena Padovan, Robert Pick, Martin Canis, Christian Schulz, Matthias Mack, Ewgenija Gutjahr, Peter Sinn, Jörg Heil, Katja Steiger, Sandip M Kanse, Wilko Weichert, Markus Sperandio, Kirsten Lauber, Fritz Krombach, Christoph A Reichel
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract High intratumoral levels of urokinase‐type plasminogen activator (uPA)‐plasminogen activator inhibitor‐1 (PAI‐1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protei
Externí odkaz:
https://doaj.org/article/4c70973c2a744ff8b94cdcdb9b282bf8
Autor:
Maria Benito-Jardón, Sarah Klapproth, Irene Gimeno-LLuch, Tobias Petzold, Mitasha Bharadwaj, Daniel J Müller, Gabriele Zuchtriegel, Christoph A Reichel, Mercedes Costell
Publikováno v:
eLife, Vol 6 (2017)
Fibronectin (FN), a major extracellular matrix component, enables integrin-mediated cell adhesion via binding of α5β1, αIIbβ3 and αv-class integrins to an RGD-motif. An additional linkage for α5 and αIIb is the synergy site located in close pr
Externí odkaz:
https://doaj.org/article/d59eaa5647354e958f6c65b866c00605
Autor:
Christoph A Reichel, Maximilian E T Hessenauer, Kerstin Pflieger, Markus Rehberg, Sandip M Kanse, Stefan Zahler, Fritz Krombach, Alexander Berghaus, Sebastian Strieth
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116883 (2015)
Rapid fibrovascularization is a prerequisite for successful biomaterial engraftment. In addition to their well-known roles in fibrinolysis, urokinase-type plasminogen activator (uPA) and tissue plasminogen activator (tPA) or their inhibitor plasminog
Externí odkaz:
https://doaj.org/article/e481b81df87b4b4e82b831b0194ae9d9
Autor:
Enxian Shi, Zhengquan Wu, Birnur Sinem Karaoglan, Sabina Schwenk-Zieger, Gisela Kranz, Nilofer Abdul Razak, Christoph A. Reichel, Martin Canis, Philipp Baumeister, Reinhard Zeidler, Olivier Gires
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-20 (2023)
Abstract Background Epithelial-to-mesenchymal transition (EMT) of malignant cells is a driving force of disease progression in human papillomavirus-negative (HPV-negative) head and neck squamous cell carcinomas (HNSCC). Sustained hyper-activation of
Externí odkaz:
https://doaj.org/article/a19c6c69db73497296f9698ab827c111
Autor:
Christoph A Reichel, Max Lerchenberger, Bernd Uhl, Markus Rehberg, Nina Berberich, Stefan Zahler, Matthias P Wymann, Fritz Krombach
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17229 (2011)
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaste
Externí odkaz:
https://doaj.org/article/9f20a55c123c4dfeae4eefe5ebad8b90
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-19 (2023)
Abstract Background The microvascular endothelium inherently controls nutrient delivery, oxygen supply, and immune surveillance of malignant tumors, thus representing both biological prerequisite and therapeutic vulnerability in cancer. Recently, cel
Externí odkaz:
https://doaj.org/article/67bea446d8134c2a972758860be7ad30
Autor:
Bernd Uhl, Florian Haring, Julia Slotta-Huspenina, Joshua Luft, Vera Schneewind, Jonas Hildinger, Zhengquan Wu, Katja Steiger, Bojan Smiljanov, Aarif M. N. Batcha, Oliver T. Keppler, Johannes C. Hellmuth, Tobias Lahmer, Konrad Stock, Bernhard G. Weiss, Martin Canis, Konstantin Stark, Thomas Bromberger, Markus Moser, Christian Schulz, Wilko Weichert, Gabriele Zuchtriegel, Christoph A. Reichel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Microvascular immunothrombotic dysregulation is a critical process in the pathogenesis of severe systemic inflammatory diseases. The mechanisms controlling immunothrombosis in inflamed microvessels, however, remain poorly understood. Here, we report
Externí odkaz:
https://doaj.org/article/ade407ee878a42518dbdd312efef54f7
Autor:
Tobias F. Primke, Rebecca Ingelfinger, Mohammed A. F. Elewa, Igor Macinkovic, Andreas Weigert, Matthias P. Fabritius, Christoph A. Reichel, Angelika Ullrich, Uli Kazmaier, Luisa D. Burgers, Robert Fürst
Publikováno v:
Cells, Vol 12, Iss 16, p 2112 (2023)
The anti-inflammatory effects of depolymerizing microtubule-targeting agents on leukocytes are known for a long time, but the potential involvement of the vascular endothelium and the underlying mechanistic basis is still largely unclear. Using the r
Externí odkaz:
https://doaj.org/article/0aefd39697be478ca324db28bd49dec4
Autor:
Gabriele Zuchtriegel, Bernd Uhl, Robert Pick, Michaela Ramsauer, Julian Dominik, Laura A. Mittmann, Martin Canis, Sandip Kanse, Markus Sperandio, Fritz Krombach, Christoph A. Reichel
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
The recruitment of neutrophils from the microvasculature to the site of injury or infection represents a key event in the inflammatory response. Vitronectin (VN) is a multifunctional macromolecule abundantly present in blood and extracellular matrix.
Externí odkaz:
https://doaj.org/article/8d9ad4479b9e45e684bcfe0a8b6d74ae
Autor:
Veronika Volgger, Stephan T. Ledderose, Evelyn Bienenstein, Christoph Walz, Matthias Hermann, Michael Nitsche, Kariem Sharaf, Tanija Hüttl, Moritz Wildgruber, Hille Kisch-Wedel, Christoph A. Reichel
Publikováno v:
HNO. 70:691-695