Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christoph A Gebeshuber"'
Autor:
Eva Nora Bukosza, Klaus Kratochwill, Christoph Kornauth, Helga Schachner, Christoph Aufricht, Christoph A Gebeshuber
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231898 (2020)
Loss of podocyte differentiation can cause nephrotic-range proteinuria and Focal and Segmental Glomerulosclerosis (FSGS). As specific therapy is still lacking, FSGS frequently progresses to end-stage renal disease. The exact molecular mechanisms of F
Externí odkaz:
https://doaj.org/article/3c18bbd365214377b3495469e9c7425d
Autor:
Michael Boehm, Eva Nora Bukosza, Nicole Huttary, Rebecca Herzog, Christoph Aufricht, Klaus Kratochwill, Christoph A Gebeshuber
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214332 (2019)
Focal and Segmental Glomerulosclerosis (FSGS) is a severe glomerulopathy that frequently leads to end stage renal disease. Only a subset of patients responds to current therapies, making it important to identify alternative therapeutic options. The i
Externí odkaz:
https://doaj.org/article/a612a8e8069b48e1a4d81bc1ef721dde
Autor:
Christoph A. Gebeshuber, Lisa Daniel-Fischer, Heinz Regele, Helga Schachner, Christoph Aufricht, Christoph Kornauth, Matthias Ley, Seth L. Alper, Rebecca Herzog, Klaus Kratochwill, Paul Perco
Publikováno v:
Translational Research.
Autor:
Christoph A. Gebeshuber, Christoph Kornauth, Christoph Aufricht, Helga Schachner, Klaus Kratochwill, Eva Nora Bukosza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0231898 (2020)
PLoS ONE, Vol 15, Iss 4, p e0231898 (2020)
Loss of podocyte differentiation can cause nephrotic-range proteinuria and Focal and Segmental Glomerulosclerosis (FSGS). As specific therapy is still lacking, FSGS frequently progresses to end-stage renal disease. The exact molecular mechanisms of F
Autor:
Christoph Aufricht, Christoph Kornauth, Klaus Kratochwill, Sigurd Krieger, Nicole Huttary, Helga Schachner, Christoph A. Gebeshuber, Ebrahim Razzazi Fazeli, André Oszwald, Gábor Szénási, Eva Nora Bukosza, Karin Hummel, Katharina Nöbauer, Péter Hamar
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2095 (2020)
Volume 21
Issue 6
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2095 (2020)
Volume 21
Issue 6
The glomerular basement membrane (GBM) and extra-cellular matrix (ECM) are essential to maintain a functional interaction between the glomerular podocytes and the fenestrated endothelial cells in the formation of the slit diaphragm for the filtration
Autor:
Christoph A. Gebeshuber, Klaus Kratochwill, Nicole Huttary, Michael Boehm, Rebecca Herzog, Christoph Aufricht, Eva Nora Bukosza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0214332 (2019)
PLoS ONE, Vol 14, Iss 3, p e0214332 (2019)
Focal and Segmental Glomerulosclerosis (FSGS) is a severe glomerulopathy that frequently leads to end stage renal disease. Only a subset of patients responds to current therapies, making it important to identify alternative therapeutic options. The i
Autor:
Christoph A. Gebeshuber, Eva-Maria Wiedemann, Sabine Maschler, Martin Schreiber, Ivana Custic, Hartmut Beug, Memetcan Alacakaptan
Publikováno v:
EMBO Molecular Medicine
Metastasis is the major cause of carcinoma-induced death, but mechanisms involved are poorly understood. Metastasis crucially involves epithelial-to-mesenchymal transition (EMT), causing loss of epithelial polarity. Here we identify Annexin A1 (AnxA1
Publikováno v:
EMBO reports. 10:400-405
Several microRNAs (miRNAs) have recently been described as crucial regulators of epithelial-to-mesenchymal transition (EMT) and metastasis. By comparing the expression profiles of miRNAs, we found upregulation of miR-29a in mesenchymal, metastatic Ra
Autor:
Stefan L. Ameres, Javier Martinez, Renée Schroeder, Christoph A. Gebeshuber, Ivo L. Hofacker, Gregor Obernosterer, Hakim Tafer
Publikováno v:
Nature Biotechnology. 26:578-583
Small-interfering RNAs (siRNAs) assemble into RISC, the RNA-induced silencing complex, which cleaves complementary mRNAs. Despite their fluctuating efficacy, siRNAs are widely used to assess gene function. Although this limitation could be ascribed,
Publikováno v:
RNA Biology. 4:165-168