Proteome2virus: Shotgun mass spectrometry data analysis pipeline for virus identification

Autor: Manon Balvers, Isabelle F. Gordijn, Ingrid A.I. Voskamp-Visser, Merel F.A. Schelling, Rob Schuurman, Esther Heikens, Rene Braakman, Christoph Stingl, Hans C. van Leeuwen, Theo M. Luider, Lennard J. Dekker, Evgeni Levin, Armand Paauw

Publikováno v: Journal of Clinical Virology Plus, Vol 3, Iss 2, Pp 100147- (2023)

Objectives: Shotgun proteomics is a generic method enabling detection of multiple viral species in one assay. The reliable and accurate identification of these viral species by analyzing peptides from MS-spectra is a challenging task. The aim of this

Externí odkaz: https://doaj.org/article/4e3ff4238d774e60832de8aa124cc2c4

Cerebrospinal Fluid of Preeclamptic and Normotensive Pregnant Women Compared to Nonpregnant Women Analyzed with Mass Spectrometry

Autor: Coşkun Güzel, Caroline B. van den Berg, Seppe Koopman, Robbert Jan van Krugten, Marcel Stoop, Christoph Stingl, Johannes J. Duvekot, Theo M. Luider

Publikováno v: ACS Omega, Vol 5, Iss 50, Pp 32256-32266 (2020)

Externí odkaz: https://doaj.org/article/d10d361083814909b286647102942d03

Supplementary Figures S1-S6 from Survivin Autoantibodies Are Not Elevated in Lung Cancer When Assayed Controlling for Specificity and Smoking Status

Autor: Theo M. Luider, Jan Lindemans, Joachim G. Aerts, Rob J. van Klaveren, Harry J. de Koning, Anastasios E. Germenis, Lennard J.M. Dekker, Christoph Stingl, Martijn M. VanDuijn, Ingrid Broodman

Supplementary Figure 1. Standard curve of rabbit monoclonal antibody to recombinant survivin using DAC-ELISA (A) and sandwich ELISA (B). Supplementary Figure 2. Antibody response to recombinant survivin was measured in seven NSCLC sera previously rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67c9f7ccc9c1f85991556ca9e95e504
https://doi.org/10.1158/2326-6066.22537894.v1

Exploring antimicrobial resistance to beta-lactams, aminoglycosides and fluoroquinolones in E. coli and K. pneumoniae using proteogenomics

Autor: Christoph Stingl, Annelies Verbon, Marian T. ten Kate, Corné H. W. Klaassen, Dimard E. Foudraine, Wil H. F. Goessens, Nikolaos Strepis, Lennard J. M. Dekker, Theo M. Luider

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, 11(1):12472. Nature Publishing Group
Scientific Reports

Antimicrobial resistance is mostly studied by means of phenotypic growth inhibition determinations, in combination with PCR confirmations or further characterization by means of whole genome sequencing (WGS). However, the actual proteins that cause r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd86f4acb0dc7a6b1fb7ab03c398a21
https://doaj.org/article/6d00242b050542c894eac474b96ad442

Novel Antibody–Peptide Binding Assay Indicates Presence of Immunoglobulins against EGFR Phospho-Site S1166 in High-Grade Glioma

Autor: Lona Zeneyedpour, Christoph Stingl, Johan M. Kros, Peter A. E. Sillevis Smitt, Theo M. Luider

Publikováno v: International Journal of Molecular Sciences, 23(9):5061. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 5061

We investigated the feasibility of detecting the presence of specific autoantibodies against potential tumor-associated peptide antigens by enriching these antibody–peptide complexes using Melon Gel resin and mass spectrometry. Our goal was to find

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07de2555ef4c16171bd0cbd939e3ee59
https://pure.eur.nl/en/publications/57606679-f600-4f40-b85e-7648f623e2ed