Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Christoph, Walz"'
Autor:
Benedek Dankó, Julia Hess, Kristian Unger, Daniel Samaga, Christoph Walz, Axel Walch, Na Sun, Philipp Baumeister, Peter Y. F. Zeng, Franziska Walter, Sebastian Marschner, Richard Späth, Olivier Gires, Timm Herkommer, Ramin Dazeh, Thaina Matos, Lisa Kreutzer, Johann Matschke, Katharina Eul, Frederick Klauschen, Ulrike Pflugradt, Martin Canis, Ute Ganswindt, Joe S. Mymryk, Barbara Wollenberg, Anthony C. Nichols, Claus Belka, Horst Zitzelsberger, Kirsten Lauber, Martin Selmansberger
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-20 (2024)
Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous malignancy that remains a significant challenge in clinical management due to frequent treatment failures and pronounced therapy resistance. While metabolic dysregulation appea
Externí odkaz:
https://doaj.org/article/478152ef0db84845b323352406d212bd
Molecular characterization of the evolution of premalignant lesions in the upper aerodigestive tract
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionEarly relapse and development of metastatic disease are some of the primary reasons for the poor prognosis of patients with head and neck squamous cell carcinoma (HNSCC). HNSCC is a heterogeneous disease which may develop in large premali
Externí odkaz:
https://doaj.org/article/0f4d5ded44514cd896064cd9c1d68777
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Elisabeth Neumann, Julia Radan, Maren Mokelke, Ines Buttgereit, Maria Leuschen, Felicia Wall, Sebastian Michel, Reinhard Ellgass, Stig Steen, Audrius Paskevicius, Andreas Lange, Barbara Kessler, Elisabeth Kemter, Nikolai Klymiuk, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Jonathan M. Burgmann, Constança Figueiredo, Anastasia Milusev, Valentina Zollet, Neda Salimi-Afjani, Alain Despont, Robert Rieben, Stephan Ledderose, Christoph Walz, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Uli Binder, Michaela Gebauer, Arne Skerra, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1927 (2024)
The blockade of the CD40/CD40L immune checkpoint is considered essential for cardiac xenotransplantation. However, it is still unclear which single antibody directed against CD40 or CD40L (CD154), or which combination of antibodies, is better at prev
Externí odkaz:
https://doaj.org/article/8c1badf713bc4998ad88ccdb88bead35
Autor:
Sophie Carina Kunte, Julian A. Marschner, Martin Klaus, Tâmisa Honda, Chenyu Li, Manga Motrapu, Christoph Walz, Maria Lucia Angelotti, Giulia Antonelli, Maria Elena Melica, Letizia De Chiara, Roberto Semeraro, Peter J. Nelson, Hans-Joachim Anders
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe NLRP3 inflammasome integrates several danger signals into the activation of innate immunity and inflammation by secreting IL-1β and IL-18. Most published data relate to the NLRP3 inflammasome in immune cells, but some reports claim sim
Externí odkaz:
https://doaj.org/article/c7087d3bdab64939a213300b01b96044
Autor:
Henrik Schinke, Enxian Shi, Zhongyang Lin, Tanja Quadt, Gisela Kranz, Jiefu Zhou, Hongxia Wang, Julia Hess, Steffen Heuer, Claus Belka, Horst Zitzelsberger, Udo Schumacher, Sandra Genduso, Kristoffer Riecken, Yujing Gao, Zhengquan Wu, Christoph A. Reichel, Christoph Walz, Martin Canis, Kristian Unger, Philipp Baumeister, Min Pan, Olivier Gires
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-25 (2022)
Abstract Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC). However, response to EGFR treatment is inconsistent and lacks markers for treatm
Externí odkaz:
https://doaj.org/article/95531d59b79a463e83a7c5658acca70f
Publikováno v:
Asian Journal of Urology, Vol 9, Iss 3, Pp 343-345 (2022)
Externí odkaz:
https://doaj.org/article/4ac9490b396046bcb44d37eac29afcdb
Autor:
Julian Kolorz, Salih Demir, Adrian Gottschlich, Iris Beirith, Matthias Ilmer, Daniel Lüthy, Christoph Walz, Mario M. Dorostkar, Thomas Magg, Fabian Hauck, Dietrich von Schweinitz, Sebastian Kobold, Roland Kappler, Michael Berger
Publikováno v:
Current Oncology, Vol 29, Iss 1, Pp 94-110 (2021)
Rhabdoid tumors (RT) are among the most aggressive tumors in early childhood. Overall survival remains poor, and treatment only effectively occurs at the cost of high toxicity and late adverse effects. It has been reported that the neurokinin-1 recep
Externí odkaz:
https://doaj.org/article/b4d76b70588949f19417df65d47f2b16
Autor:
Jiefu Zhou, Sabina Schwenk-Zieger, Gisela Kranz, Christoph Walz, Frederik Klauschen, Sharduli Dhawan, Martin Canis, Olivier Gires, Frank Haubner, Philipp Baumeister, Vera Kohlbauer
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionHead and neck squamous cell carcinomas (HNSCC) are characterized by strong cellular and molecular heterogeneity and treatment resistance entailing poor survival. Besides cell-intrinsic properties, carcinoma cells receive important cues fr
Externí odkaz:
https://doaj.org/article/ca1fb1c4d8af49d0bd27054ec938fdf6
Autor:
Kariem Sharaf, Axel Lechner, Stefan P. Haider, Robert Wiebringhaus, Christoph Walz, Gisela Kranz, Martin Canis, Frank Haubner, Olivier Gires, Philipp Baumeister
Publikováno v:
Current Oncology, Vol 28, Iss 4, Pp 2763-2774 (2021)
Cancer stem cells (CSCs) are accountable for the progress of head and neck squamous cell carcinoma (HNSCC). This exploratory study evaluated the expression of molecular CSC markers in different tissues of HNSCC patients. Tissue specimens of primary t
Externí odkaz:
https://doaj.org/article/856ba980079f4b48a56d8fc599560588
Autor:
Henrik Schinke, Theresa Heider, Timm Herkommer, Florian Simon, Alexandra Blancke Soares, Gisela Kranz, Daniel Samaga, Laura Dajka, Annette Feuchtinger, Axel Walch, Laura Valeanu, Christoph Walz, Thomas Kirchner, Martin Canis, Philipp Baumeister, Claus Belka, Cornelius Maihöfer, Sebastian Marschner, Ulrike Pflugradt, Ute Ganswindt, Julia Hess, Horst Zitzelsberger, Olivier Gires
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 1040-1053 (2021)
Head and neck squamous cell carcinomas (HNSCCs) have poor clinical outcome owing to therapy resistance and frequent recurrences that are among others attributable to tumor cells in partial epithelial‐to‐mesenchymal transition (pEMT). We compared
Externí odkaz:
https://doaj.org/article/38a6ed8f49fc46aeb9c0fc77e0558f6a