Collaborative Challenges of Multi-Cohort Projects in Pharmacogenetics—Why Time Is Essential for Meaningful Collaborations

Autor: Filippo Franchini, Katharina Kusejko, Catia Marzolini, Christoph Tellenbach, Simona Rossi, Susanne Stampf, Michael Koller, Jivko Stoyanov, Burkhard Möller, Alexander Benedikt Leichtle

Publikováno v: JMIR Formative Research, Vol 6, Iss 9, p e36759 (2022)

Multi-cohort projects in medicine provide an opportunity to investigate scientific questions beyond the boundaries of a single institution and endeavor to increase the sample size for obtaining more reliable results. However, the complications of the

Externí odkaz: https://doaj.org/article/cc949cb42b154486a2f042fcfbf54909

Collaborative challenges of multi-cohort project in pharmacogenetics: why time is essential for meaningful collaborations (Preprint)

Autor: Filippo Franchini, Katharina Kusejko, Catia Marzolini, Christoph Tellenbach, Simona Rossi, Susanne Stampf, Michael Koller, Jivko Stoyanov, Burkhard Möller, Alexander Benedikt Leichtle

UNSTRUCTURED Multi-cohort projects in medicine provide an opportunity to investigate scientific questions beyond the boundaries of a single institution, and to increase sample size for more reliable results. However, the complications of these kinds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05d4a29a197cda988fded0a46403d2b6
https://doi.org/10.2196/preprints.36759

Parasites driving host diversity: Incidence of disease correlated withDaphniaclonal turnover*

Autor: Patrick Turko, Piet Spaak, Justyna Wolinska, Barbara Keller, Nadine Tardent, Christoph Tellenbach, Esther Keller

Publikováno v: Evolution. 72:619-629

According to the Red Queen hypothesis, clonal diversity in asexual populations could be maintained by negative frequency-dependant selection by coevolving parasites. If common clones are selected against and rare clones gain a concomitant advantage,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8efc45d0276b211de3228d21d064f201
https://doi.org/10.1111/evo.13413

Daphnia parasite dynamics across multiple Caullerya epidemics indicate selection against common parasite genotypes

Autor: Sabine Gießler, Justyna Wolinska, Enrique González-Tortuero, Lubomír Piálek, Piet Spaak, Adam Petrusek, Jakub Rusek, Inbar Maayan, Patrick Turko, Christoph Tellenbach

Publikováno v: Zoology. 119:314-321

Studies of parasite population dynamics in natural systems are crucial for our understanding of host-parasite coevolutionary processes. Some field studies have reported that host genotype frequencies in natural populations change over time according

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eda1ca408dee184fb0993803fc6e729
https://doi.org/10.1016/j.zool.2016.04.003

Using DNA from formaldehyde-preserved Daphnia to reconstruct past populations

Autor: Patrick Turko, Marie-Eve Monchamp, Christoph Tellenbach, Piet Spaak, Marcin Krzysztof Dziuba, Justyna Wolinska

Publikováno v: Turko, P, Wolinska, J, Tellenbach, C, Dziuba, M K, Monchamp, M-E & Spaak, P 2019, ' Using DNA from formaldehyde-preserved Daphnia to reconstruct past populations ', Hydrobiologia, vol. 841, no. 1, pp. 153-161 . https://doi.org/10.1007/s10750-019-04015-0

We compared taxon composition of the Daphnia longispina hybrid community, as reconstructed from dormant eggs (retrieved from sediment samples) and the pelagic population (retrieved from formaldehyde-preserved zooplankton samples), from the same lake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d6f83b4e1eeac272cdd137fcfdbc7d
https://curis.ku.dk/ws/files/250354116/Using_DNA_from_formaldehyde_preserved_Daphnia_to_reconstruct_past_populations_accepted_version_.pdf