Zobrazeno 1 - 10
of 418
pro vyhledávání: '"Christoph, Peter"'
Autor:
Laura Schmitt, Karina S. Krings, Andre Wolsing, Xabier Buque, Marcel Zimmermann, Hector Flores-Romero, Thomas Lenz, Ilka Lechtenberg, Christoph Peter, Björn Stork, Nicole Teusch, Peter Proksch, Kai Stühler, Ana J. García-Sáez, Andreas S. Reichert, Patricia Aspichueta, Sanil Bhatia, Sebastian Wesselborg
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Targeting mitochondrial metabolism represents a promising approach for cancer treatment. Here, we investigated the mitotoxic potential of the polybrominated diphenyl ether bromoxib, a natural compound isolated from the marine sponge Dysidea
Externí odkaz:
https://doaj.org/article/9172168f3c784c2f8b3a4f970bd907a9
Autor:
Laura Schmitt, Julia Hoppe, Pablo Cea-Medina, Peter-Martin Bruch, Karina S. Krings, Ilka Lechtenberg, Daniel Drießen, Christoph Peter, Sanil Bhatia, Sascha Dietrich, Björn Stork, Gerhard Fritz, Holger Gohlke, Thomas J. J. Müller, Sebastian Wesselborg
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract A key feature of cancer is the disruption of cell cycle regulation, which is characterized by the selective and abnormal activation of cyclin-dependent kinases (CDKs). Consequently, targeting CDKs via meriolins represents an attractive thera
Externí odkaz:
https://doaj.org/article/63272546db6a4c5fbc60190ad36400b2
Autor:
Laura Schmitt, Ilka Lechtenberg, Daniel Drießen, Hector Flores-Romero, Margaretha A. Skowron, Marlena Sekeres, Julia Hoppe, Karina S. Krings, Tanya R. Llewellyn, Christoph Peter, Björn Stork, Nan Qin, Sanil Bhatia, Daniel Nettersheim, Gerhard Fritz, Ana J. García-Sáez, Thomas J. J. Müller, Sebastian Wesselborg
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Meriolin derivatives represent a new class of kinase inhibitors with a pronounced cytotoxic potential. Here, we investigated a newly synthesized meriolin derivative (termed meriolin 16) that displayed a strong apoptotic potential in Jurkat l
Externí odkaz:
https://doaj.org/article/bb0b5a2076ab4d3192f705aa5b86dbd2
Autor:
Lucieri, Adriano, Schmeisser, Fabian, Balada, Christoph Peter, Siddiqui, Shoaib Ahmed, Dengel, Andreas, Ahmed, Sheraz
It is generally believed that the human visual system is biased towards the recognition of shapes rather than textures. This assumption has led to a growing body of work aiming to align deep models' decision-making processes with the fundamental prop
Externí odkaz:
http://arxiv.org/abs/2206.06466
Autor:
Christoph Peter, Martin Tajmar
Publikováno v:
IEEE Access, Vol 12, Pp 114618-114625 (2024)
A method for optimizing multiple responses in solenoids utilized in a magnetic nozzle assembly for an electric plasma thruster is presented. The primary goal is to minimize power usage while maintaining a sufficiently high magnetic flux density at th
Externí odkaz:
https://doaj.org/article/f1c3b7c364bf4943970f08a8c29f3b3a
The problem of finding K-nearest neighbors in the given dataset for a given query point has been worked upon since several years. In very high dimensional spaces the K-nearest neighbor search (KNNS) suffers in terms of complexity in computation of hi
Externí odkaz:
http://arxiv.org/abs/2102.06525
Autor:
Zimmer, Valerie Christin, Lauer, Anna Andrea, Haupenthal, Viola, Stahlmann, Christoph Peter, Mett, Janine, Grösgen, Sven, Hundsdörfer, Benjamin, Rothhaar, Tatjana, Endres, Kristina, Eckhardt, Matthias, Hartmann, Tobias, Grimm, Heike Sabine, Grimm, Marcus Otto Walter
Publikováno v:
In Cell Chemical Biology 15 February 2024 31(2):265-283
Autor:
Silvia Schest, Claus Langer, Yuriko Stiegler, Bianca Karnuth, Jan Arends, Hugo Stiegler, Thomas Masetto, Christoph Peter, Matthias Grimmler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundQuantification of the SARS-CoV-2-specific immune response by serological immunoassays is critical for the management of the COVID-19 pandemic. In particular, neutralizing antibody titers to the viral spike (S) protein have been proposed as
Externí odkaz:
https://doaj.org/article/1fc3eed9b5544c78995a5ed09e1512f6
Autor:
Hofmann, Christoph Peter
We investigate the thermodynamic behavior of antiferromagnetic films in external magnetic fields oriented perpendicular to the staggered magnetization. Within the systematic effective Lagrangian framework we first calculate the two-point function and
Externí odkaz:
http://arxiv.org/abs/1812.04392
Autor:
Lea Marie Esser, Katharina Schmitz, Frank Hillebrand, Steffen Erkelenz, Heiner Schaal, Björn Stork, Matthias Grimmler, Sebastian Wesselborg, Christoph Peter
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2100-2109 (2023)
The spliceosome, responsible for all mature protein-coding transcripts of eukaryotic intron-containing genes, consists of small uridine-rich nuclear ribonucleoproteins (UsnRNPs). The assembly of UsnRNPs depends, on one hand, on the arginine methylati
Externí odkaz:
https://doaj.org/article/104567e091404490bf1af5bf1619f414