Supplementary appendix from Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non–Small Cell Lung Cancer: Efficacy, Safety, and Biomarkers

Autor: Thomas E. Stinchcombe, Michael W. Lu, Lisa H. Lam, Sanne de Haas, Christoph Meyenberg, Marcello Tiseo, Achim Rittmeyer, Pilar Garrido, Javier De Castro Carpeno, Dolores Isla, Christina S. Baik, Dariusz M. Kowalski, Augusto Villegas, Philip Bonomi, Lukas Bubendorf, Rolf Stahel, Solange Peters

Supplementary appendix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4121109b492808668e044a0750d98691
https://doi.org/10.1158/1078-0432.22472889.v1

Efficacy and safety of balovaptan for socialisation and communication difficulties in autistic adults in North America and Europe: a phase 3, randomised, placebo-controlled trial

Autor: Suma, Jacob, Jeremy, Veenstra-VanderWeele, Declan, Murphy, James, McCracken, Janice, Smith, Kevin, Sanders, Christoph, Meyenberg, Thomas, Wiese, Gurpreet, Deol-Bhullar, Christoph, Wandel, Elizabeth, Ashford, Evdokia, Anagnostou

Publikováno v: The Lancet Psychiatry. 9:199-210

There are no approved pharmacological therapies to support treatment of the core communication and socialisation difficulties associated with autism spectrum disorder in adults. We aimed to assess the efficacy, safety, and pharmacokinetics of balovap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373a65dc2819296ad266928f1a472841
https://doi.org/10.1016/s2215-0366(21)00429-6

Regulatory cell therapy in kidney transplantation (The ONE Study):a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

Autor: Kathryn J. Wood, Birgit Sawitzki, James A. Hutchinson, Leslie Brent, Cristiano Scottà, Christoph Meyenberg, P Friend, Kerry Crisalli, Manuela Battaglia, Natalie M Otto, Ben James, Eva C. Guinan, M. C. Cuturi, Alexander Scheffold, William Petchey, Ulrich Kunzendorf, William J. Burlingham, Fadi Issa, Antonio Secchi, Petra Reinke, Giovanna Lombardi, James F. Markmann, Hans-Dieter Volk, David Game, Matthias Edinger, Norbert Ahrens, Ian S.D. Roberts, Michael Kapinsky, Maria P. Hernandez-Fuentes, Bernhard Banas, Sandra Karitzky, Nathalie Dupas, Carsten A. Böger, Edward K. Geissler, Tewfik Miloud, Stephan Schlickeiser, Paul N. Harden, Qizhi Tang, Gilles Blancho, Tobias Bergler, Karsten Juerchott, Robert I. Lechler, Hans J. Schlitt, Josep M. Grinyó, Laura Contreras-Ruiz, Rossana Caldara, Joanna Hester, Mathias Streitz, A. Bushell, Rachel Hilton, Régis Josien, Stuart J. Knechtle, Robert Öllinger, Laurence A. Turka, Cécile Braudeau, Aurélie Moreau, Peter J. Morris, Jeffrey A. Bluestone, Sang-Mo Kang, Ingrid Mutzbauer, Jeroen B. van der Net

Publikováno v: Sawitzki, B, Harden, P, Reinke, P, Moreau, A, Hutchinson, J A, Game, D S, Tang, Q, Guinan, E, Battaglia, M, Burlingham, W J, Roberts, I, Streitz, M, Josien, R, Böger, C A, Scotta, C, Markmann, J F, Hester, J, Juerchott, K, Braudeau, C, James, B, Contreras-Ruiz, L, van der Net, J B, Bergler, T, Caldara, R, Petchey, W, Edinger, M, Dupas, N, Kapinsky, M, Mutzbauer, I, Otto, N M, Ollinger, R, Hernandez Fuentes, M, Issa, F, Ahrens, N, Meyenberg, C, Karitzky, S, Kunzendorf, U, Knechtle, S J, Grinyo, J, Morris, P J, Brent, L, Bushell, A, Turka, L A, Bluestone, J A, Lechler, R, Schlitt, H J, Cuturi, M C, Schlickeiser, S, Friend, P J, Miloud, T, Scheffold, A, Secchi, A, Crisalli, K, Kang, S-M, Hilton, R, Banas, B, Blancho, G, Volk, H-D, Lombardi, G, Wood, K & Geissler, E K 2020, ' Regulatory cell therapy in kidney transplantation (The ONE Study) : a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials ', The Lancet, vol. 395, no. 10237, pp. 1627-1639 . https://doi.org/10.1016/S0140-6736(20)30167-7
Lancet (London, England), vol 395, iss 10237

Background:Use of cell-based medicinal products (CBMPs) represents a state-of-the-art approach for reducing general immunosuppression in organ transplantation. We tested multiple regulatory CBMPs in kidney transplant trials to establish the safety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeb3a2997cd38b689087979f243f237
https://kclpure.kcl.ac.uk/ws/files/125216985/AllTogetherFigs.pdf

6.14 PHASE 3 RANDOMIZED CONTROLLED TRIAL OF BALOVAPTAN IN ADULTS WITH AUTISM SPECTRUM DISORDER

Autor: Suma Jacob, Jeremy Veenstra-VanderWeele, Declan Murphy, James T. McCracken, Janice Smith, Kevin Sanders, Christoph Meyenberg, Thomas Wiese, Gurpreet Deol-Bhullar, Christoph Wandel, Evdokia Anagnostou

Publikováno v: Journal of the American Academy of Child & Adolescent Psychiatry. 59:S163-S164

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff6cabd8e8628ffa5ee67335152b4bcc
https://doi.org/10.1016/j.jaac.2020.08.108

ALINA: A phase III study of alectinib versus chemotherapy as adjuvant therapy in patients with stage IB–IIIA anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC)

Autor: Alice T. Shaw, Benjamin Solomon, Makoto Nishio, Christoph Meyenberg, Walter Bordogna, Jin Seok Ahn, Yi-Long Wu, Fabrice Barlesi, Rafal Dziadziuszko

Publikováno v: Journal of Clinical Oncology. 37:TPS8569-TPS8569

TPS8569 Background: Patients with early-stage NSCLC (stage IA–IIIA) account for ~40% of cases at diagnosis; despite surgery, 5-year survival rates are low. Platinum-based adjuvant chemotherapy is the standard of care (SoC) for stage II–IIIA disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3d9b9c71877281634f6b9887c856bc2
https://doi.org/10.1200/jco.2019.37.15_suppl.tps8569