Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Christoph, Mamot"'
Autor:
Susanne Rogers, Markus Gross, Ekin Ermis, Gizem Cosgun, Brigitta G. Baumert, Thomas Mader, Christina Schroeder, Nicoletta Lomax, Sara Alonso, Adela Ademaj, Tessa Lazeroms, Seok-Yun Lee, Michael Mayinger, Christoph Mamot, Lucia Schwyzer, Gerrit A. Schubert, Oliver Riesterer
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background 90% of glioblastomas (GBM) relapse within two years of diagnosis. In contrast to the initial setting, there is no standard management for recurrent disease and options include hypofractionated stereotactic re-irradiation (re-mHSRT
Externí odkaz:
https://doaj.org/article/b2c18a859f75458dbc5353877d4d233b
Autor:
Christoph Mamot, Andreas Wicki, Ursula Hasler-Strub, Salome Riniker, Qiyu Li, Lisa Holer, Daniela Bärtschi, Khalil Zaman, Roger von Moos, Konstantin J. Dedes, Laura A. Boos, Urban Novak, Alexandre Bodmer, Reto Ritschard, Ellen C. Obermann, Alexandar Tzankov, Christoph Ackermann, Véronique Membrez-Antonioli, Ursina Zürrer-Härdi, Clemens B. Caspar, Stefanie Deuster, Martin Senn, Ralph Winterhalder, Christoph Rochlitz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Advanced triple negative breast cancer (TNBC) is an aggressive, but initially chemo-sensitive disease. The prognosis is poor and more than three quarters of patients experience progression 12 months after the initiation of conventional first
Externí odkaz:
https://doaj.org/article/1eb3fffffd304a00942ffdd17ebd7e8a
Autor:
Sabine Schmid, Dirk Klingbiel, Stefan Aebi, Aron Goldhirsch, Christoph Mamot, Elisabetta Munzone, Franco Nolè, Christian Oehlschlegel, Olivia Pagani, Bernhard Pestalozzi, Christoph Rochlitz, Beat Thürlimann, Roger von Moos, Patrik Weder, Khalil Zaman, Thomas Ruhstaller
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background The impact of HER2-targeted therapy alone followed by the addition of chemotherapy at disease progression (PD) versus upfront combination was investigated by the SAKK 22/99 trial. The aim of this exploratory analysis of the SAKK 2
Externí odkaz:
https://doaj.org/article/3a71b23e5f6e4fdeb49b83bd63c454c7
Autor:
Patrick Roth, Andreas F. Hottinger, Thomas Hundsberger, Heinz Läubli, Philippe Schucht, Michael Reinert, Christoph Mamot, Ulrich Roelcke, Gianfranco Pesce, Silvia Hofer, Michael Weller
Publikováno v:
Swiss Medical Weekly, Vol 150, Iss 2324 (2020)
Gliomas are intrinsic brain tumours, which are classified by the World Health Organization (WHO) into different grades of malignancy, with glioblastoma being the most frequent and most malignant subtype (WHO grade IV). Mutations in the isocitrate deh
Externí odkaz:
https://doaj.org/article/209d3cdc8370416b8113b2789c1ca1cf
Autor:
Niloy Ranjan Datta, Bernhard Pestalozzi, Pierre-Alain Clavien, Alexander Siebenhüner, Emsad Puric, Shaka Khan, Christoph Mamot, Oliver Riesterer, Jürg Knuchel, Cäcilia Sophie Reiner, Stephan Bodis, members of the HEATPAC Trial Group
Publikováno v:
Radiation Oncology, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Background Pancreatic cancer has a dismal prognosis with 5-year overall survival rate of around 5%. Although surgery is still the best option in operable cases, majority of the patients who present in locally advanced stages are deemed inope
Externí odkaz:
https://doaj.org/article/f5b25d045de54fb1b9b9c1f1518d6b4c
Autor:
Darius Juskevicius, David Jucker, Dirk Klingbiel, Christoph Mamot, Stephan Dirnhofer, Alexandar Tzankov
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-10 (2017)
Abstract Background/purpose Recently, the mutational background of diffuse large B cell lymphoma (DLBCL) has been revealed, identifying specific genetic events that drive lymphomagenesis. However, the prognostic value of these mutations remains to be
Externí odkaz:
https://doaj.org/article/f783188417e3474e953a6efd0599eec5
Autor:
Andrew J Davies, Louise Stanton, Josh Caddy, Sharon Barrans, Sam Wilding, Geoff N Saunders, Christoph Mamot, Urban Novak, Andrew K. McMillan, Paul A Fields, Graham P. Collins, Richard Stephens, Francesco Cucco, Chulin Sha, Moniek Van Hoppe, Reuben M Tooze, Matthew A Care, Gareth Griffiths, Anna Schuh, Ming-Qing Du, David R Westhead, Cathy Burton, Peter Johnson
Publikováno v:
Blood. 140:1770-1772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50ca33cdb19da6a39c58f654bfa4a6e
https://doi.org/10.1182/blood-2022-159976
https://doi.org/10.1182/blood-2022-159976
Autor:
Christoph Mamot, Gerhard Christofori, Richard Herrmann, Imke Albrecht, Reto Ritschard, Annette Orleth, Christoph Rochlitz, Andreas Wicki
PDF file - 85K, Biodistribution of anti-VEGFR2 Immunliposomes Analysis of tissue samples showed a non-significant trend to a higher concentration of ILs in parenchymal organs (lung, liver and spleen) but not in the tumor (A and B). Rip1Tag2 mice were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0490d7294f0872d9f5896dc7440d8d20
https://doi.org/10.1158/1078-0432.22444397.v1
https://doi.org/10.1158/1078-0432.22444397.v1
Autor:
Christoph Mamot, Gerhard Christofori, Richard Herrmann, Imke Albrecht, Reto Ritschard, Annette Orleth, Christoph Rochlitz, Andreas Wicki
PDF file - 762K, (A) Immunoliposomes bind specifically to their targets in vitro. Specific binding capacity was evaluated in MDA-MB468, a human breast cancer cell line, with endogenous overexpession of EGFR. Cells were incubated with DiIC18(3)- DS-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f85da6e6f36ff8fd726c97f7281e600
https://doi.org/10.1158/1078-0432.22444403
https://doi.org/10.1158/1078-0432.22444403
Autor:
Christoph Mamot, Gerhard Christofori, Richard Herrmann, Imke Albrecht, Reto Ritschard, Annette Orleth, Christoph Rochlitz, Andreas Wicki
PDF file - 222K, Histopathological analysis of tumor sections by staining with hematoxylin and eosin (H&E). Hemorrhagic lacunae are visible in the center of tumors treated with anti-VEGFR2 ILs-dox in the Rip1Tag2 and the MMTV-PyMT tumor mouse model (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fb3a937bb5cd4718336b3cf9fe78a9
https://doi.org/10.1158/1078-0432.22444394.v1
https://doi.org/10.1158/1078-0432.22444394.v1