Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Christoph, Kaun"'
Autor:
Manuel Salzmann, Patrick Haider, Christoph Kaun, Mira Brekalo, Boris Hartmann, Theresia Lengheimer, Rebecca Pichler, Thomas Filip, Sophia Derdak, Bruno Podesser, Christian Hengstenberg, Walter S. Speidl, Johann Wojta, Roberto Plasenzotti, Philipp J. Hohensinner
Publikováno v:
Journal of Innate Immunity, Pp 1-13 (2021)
Training of the innate immune system with orally ingested bacterial extracts was demonstrated to have beneficial effects on infection clearance and disease outcome. The aim of our study was to identify cellular and molecular processes responsible for
Externí odkaz:
https://doaj.org/article/29d288b1ebad47b4a34ad65a3bd7db21
Autor:
David Santer, Felix Nagel, Inês Fonseca Gonçalves, Christoph Kaun, Johann Wojta, Miklós Fagyas, Martin Krššák, Ágnes Balogh, Zoltán Papp, Attila Tóth, Viktor Bánhegyi, Karola Trescher, Attila Kiss, Bruno K. Podesser
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 2113-2122 (2020)
Abstract Aims Tenascin‐C (TN‐C) is suggested to be detrimental in cardiac remodelling after myocardial infarction (MI). The aim of this study is to reveal the effects of TN‐C on extracellular matrix organization and its haemodynamic influence i
Externí odkaz:
https://doaj.org/article/91ad737678b74223b8fd980be7256afe
Autor:
Svitlana Demyanets, Christoph Kaun, Alexandra Kaider, Walter Speidl, Manfred Prager, Stanislav Oravec, Philipp Hohensinner, Johann Wojta, Gersina Rega-Kaun
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background High soluble suppression of tumorigenicity-2 (sST2) is a marker of poor prognosis in chronic inflammatory conditions. ST2 and its ligand interleukin (IL)-33 are elevated in adipose tissue of obese individuals. We aimed to evaluate
Externí odkaz:
https://doaj.org/article/ca115a99e3f543319ed5ab4199d8a284
Autor:
Philipp J. Hohensinner, Julia Mayer, Julia Kichbacher, Julia Kral-Pointner, Barbara Thaler, Christoph Kaun, Lena Hell, Patrick Haider, Marion Mussbacher, Johannes A. Schmid, Stefan Stojkovic, Svitlana Demyanets, Michael B. Fischer, Kurt Huber, Katharina Wöran, Christian Hengstenberg, Walter S. Speidl, Rudolf Oehler, Ingrid Pabinger, Johann Wojta
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
Macrophages are versatile cells that can be polarized by the tissue environment to fulfill required needs. Proinflammatory polarization is associated with increased tissue degradation and propagation of inflammation whereas alternative polarization w
Externí odkaz:
https://doaj.org/article/c88174e20a0542a79f36b73e83873944
Autor:
Stefan P Kastl, Katharina M Katsaros, Konstantin A Krychtiuk, Gerlinde Jägersberger, Christoph Kaun, Kurt Huber, Johann Wojta, Walter S Speidl
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232483 (2020)
BACKGROUND:Percutaneous coronary intervention represents the most important treatment modality of coronary artery stenosis. In-stent restenosis (ISR) is still a limitation for the long-term outcome despite the introduction of drug eluting stents. It
Externí odkaz:
https://doaj.org/article/e62bb54f373f4f0fb13b7d8549f82cb7
Autor:
Nadine Maier, Constantin Gatterer, Patrick Haider, Manuel Salzmann, Christoph Kaun, Walter S. Speidl, Gere Sunder-Plassmann, Bruno K. Podesser, Johann Wojta, Senta Graf, Max Lenz, Philipp J. Hohensinner
Publikováno v:
Genes, Vol 12, Iss 8, p 1184 (2021)
Background: Fabry disease is a hereditary genetic defect resulting in reduced activity of the enzyme α-galactosidase-A and the accumulation of globotriaosylceramide (Gb3) in body fluids and cells. Gb3 accumulation was especially reported for the vas
Externí odkaz:
https://doaj.org/article/635a03a757aa41129cdf7d63e005b7c4
Autor:
Max Lenz, Christoph Kaun, Konstantin A. Krychtiuk, Patrick Haider, Mira Brekalo, Nadine Maier, Laura Goederle, Christoph J. Binder, Kurt Huber, Christian Hengstenberg, Johann Wojta, Philipp J. Hohensinner, Walter S. Speidl
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 120 (2021)
Nicorandil, a balanced vasodilator, is used in the second-line therapy of angina pectoris. In this study, we aimed to illuminate the effects of nicorandil on inflammation, apoptosis, and atherosclerotic plaque progression. Twenty-five LDL-R -/- mice
Externí odkaz:
https://doaj.org/article/00c1fe480bee427aa3c2a94493526cc2
Autor:
Katrin Zlabinger, Dominika Lukovic, Rayyan Hemetsberger, Alfred Gugerell, Johannes Winkler, Ljubica Mandic, Denise Traxler, Andreas Spannbauer, Susanne Wolbank, Gerald Zanoni, Christoph Kaun, Aniko Posa, Andrea Gyenes, Zsolt Petrasi, Örs Petnehazy, Imre Repa, Renate Hofer-Warbinek, Rainer de Martin, Florian Gruber, Silvia Charwat, Kurt Huber, Noemi Pavo, Imre J. Pavo, Noemi Nyolczas, Dara L. Kraitchman, Mariann Gyöngyösi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 6 (2018)
BackgroundIntracoronary (IC) injection of mesenchymal stem cells (MSCs) results in a prompt decrease of absolute myocardial blood flow (AMF) with late and incomplete recovery of myocardial tissue perfusion. Here, we investigated the effect of decreas
Externí odkaz:
https://doaj.org/article/2c83ac17e4f747fe8e7f7c4e74a68a46
Autor:
Patrick Haider, Julia B. Kral‐Pointner, Manuel Salzmann, Florian Moik, Sonja Bleichert, Waltraud C. Schrottmaier, Christoph Kaun, Mira Brekalo, Michael B. Fischer, Walter S. Speidl, Christian Hengstenberg, Bruno K. Podesser, Kurt Huber, Ingrid Pabinger, Sylvia Knapp, Frank Brombacher, Christine Brostjan, Cihan Ay, Johann Wojta, Philipp J. Hohensinner
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36(10)
Interleukin-4 (IL-4) and its receptors (IL-4R) promote the proliferation and polarization of macrophages. However, it is unknown if IL-4R also influences monocyte homeostasis and if steady state IL-4 levels are sufficient to affect monocytes. Employi
Autor:
Max, Lenz, Manuel, Salzmann, Cosmin I, Ciotu, Christoph, Kaun, Konstantin A, Krychtiuk, Andreja, Rehberger Likozar, Miran, Sebestjen, Laura, Goederle, Sabine, Rauscher, Zoriza, Krivaja, Christoph J, Binder, Kurt, Huber, Christian, Hengstenberg, Bruno K, Podesser, Michael J M, Fischer, Johann, Wojta, Philipp J, Hohensinner, Walter S, Speidl
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
Changes in Ca2