Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Christoph, Guetter"'
Autor:
Alyson Yoder, Landon J. Inge, Chen-Chun Chen, Vijay R. Marati, Trung Kien Nguyen, Karel Zuiderveld, Jim Martin, Sarah Gladden, Mohammad Saleh Miri, Raghavan Venugopal, Bryan Lopez, Jim Ranger-Moore, Christoph Guetter
Publikováno v:
Journal of Pathology Informatics, Vol 13, Iss , Pp 100116- (2022)
Background: Identification of HER2 protein overexpression and/or amplification of the HER2 gene are required to qualify breast cancer patients for HER2 targeted therapies. In situ hybridization (ISH) assays that identify HER2 gene amplification funct
Externí odkaz:
https://doaj.org/article/764668fb084a4a1fa50c1c01e6bd57bb
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Table S1: Baseline patient demographics and disease characteristics. Table S2: mRNA/IHC AREG/EREG concordance table. Figure S1: AREG/EREG IHC scatterplot. Table S3: Prognostic effect of dichotomous AREG/EREG. Table S4: AREG/EREG and RECIST response r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d26093065ca47cac56c3fafb14b7ba6
https://doi.org/10.1158/1078-0432.22478486.v1
https://doi.org/10.1158/1078-0432.22478486.v1
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Purpose:High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3918d1658590fe73e85875c77ed53656
https://doi.org/10.1158/1078-0432.c.6529961
https://doi.org/10.1158/1078-0432.c.6529961
Autor:
Auranuch Lorsakul, Andrea Muranyi, Uday Kurkure, Kien Nguyen, Wen-Wei Liu, Isaac Bai, Jennifer H. Barrett, Christoph Guetter, Kandavel Shanmugam, Matthew T. Seymour, Philip Quirke, Michael Barnes, Dongyao Yan, Jenny F. Seligmann, Susan D. Richman, Zuo Zhao, Nicholas P. West, Xiao-Meng Xu, Xingwei Wang, Liping Zhang, James R. Martin, Faye Elliott, Michael Shires, Christopher J.M. Williams, Sarah Brown, Judith Pugh, Shalini Singh
Publikováno v:
Clinical Cancer Research. 27:3422-3431
Purpose: High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice
Autor:
Christopher Williams, Richard G Gray, Mike Shires, Liping Zhang, Zuo Zhao, Isaac Bai, Dongyao Yan, Sarah Dance, Faranak Aghaei, Gemma Hemmings, Michael Hale, Uday Kurkure, Christoph Guetter, Susan D Richman, Gordon Hutchins, Jenny F. Seligmann, Nicholas West, Shalini Singh, Kandavel Shanmugam, Philip Quirke
Publikováno v:
Journal of Clinical Oncology. 41:204-204
204 Background: High CD3+ (all) and CD8+ (cytotoxic) T cell densities in the core (CT) and invasive margin (IM) of primary CRCs have been shown to be associated with superior prognosis at all stages of disease. Their predictive effect on benefit from
Autor:
Veena Kaustaban, Qinle Ba, Ipshita Bhattacharya, Nahil Sobh, Satarupa Mukherjee, Jim Martin, Mohammad Saleh Miri, Christoph Guetter, Amal Chaturvedi
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783031169601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04933b6504aa6b373c7fe22b764908e3
https://doi.org/10.1007/978-3-031-16961-8_18
https://doi.org/10.1007/978-3-031-16961-8_18
Autor:
Monesh Kapadia, Mehrnoush Khojasteh, Margarita Kouzova, Carol Jones, Xiao-Meng Xu, Matthew T. Olson, Sarah Gladden, Nancy Sapanara, Shalini Singh, Chen Chun Chen, Isaac Bai, Jim Ranger-Moore, Landon J. Inge, Uday Kurkure, Ipshita Bhattacharya, Margaret Zhao, Karel Zuiderveld, Chandana Chintakindi, Bryan Lopez, Christoph Guetter
Publikováno v:
Cancer Research. 82:P1-02
Background: 2.1 million breast cancers are newly diagnosed each year. Current guidelines endorse routine testing for estrogen receptor (ER) and progesterone receptor (PR), while use of the Ki67 biomarker can provide additional prognostic value. All t
Autor:
Christopher J M, Williams, Jenny F, Seligmann, Faye, Elliott, Michael, Shires, Susan D, Richman, Sarah, Brown, Liping, Zhang, Shalini, Singh, Judith, Pugh, Xiao-Meng, Xu, Andrea, Muranyi, Christoph, Guetter, Auranuch, Lorsakul, Uday, Kurkure, Zuo, Zhao, Jim, Martin, Xingwei, Wang, Kien, Nguyen, Wen-Wei, Liu, Dongyao, Yan, Nicholas P, West, Jennifer H, Barrett, Michael, Barnes, Isaac, Bai, Matthew T, Seymour, Philip, Quirke, Kandavel, Shanmugam
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(12)
High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice due to is
Autor:
Philip Quirke, Matthew T. Seymour, Susan D. Richman, Faye Elliott, Jenny F. Seligmann, Dongyao Yan, Isaac Bai, Mike Shires, Nicholas P. West, Andrea Muranyi, Jenny Barrett, Liping Zhang, Christopher Williams, Kandavel Shanmugam, Christoph Guetter, Shalini Singh
Publikováno v:
Journal of Clinical Oncology. 39:111-111
111 Background: High tumor mRNA levels of the EGFR ligands, AREG and EREG are associated with anti-EGFR agent response in patients (pts) with RAS-wt mCRC, regardless of tumor location. However, ligand RNA assays have not been adopted into routine cli
Autor:
Juliana Serafim da Silveira, Hui Xue, Paaladinesh Thavendiranathan, Marie-Pierre Jolly, Xiaoguang Lu, Debbie Scandling, Christoph Guetter, Orlando P. Simonetti, Subha V. Raman
Publikováno v:
Magnetic resonance imaging. 55
Background Doppler based mitral annular velocities are an integral part of echocardiographic left ventricular diastolic function assessment. Although these measurements can be obtained by phase contrast cardiac magnetic resonance imaging (PC-CMR), th