Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christoph, Grander"'
Autor:
Christoph Grander, Moritz Meyer, Daniel Steinacher, Thierry Claudel, Bela Hausmann, Petra Pjevac, Felix Grabherr, Georg Oberhuber, Manuel Grander, Natascha Brigo, Almina Jukic, Julian Schwärzler, Günter Weiss, Timon E. Adolph, Michael Trauner, Herbert Tilg
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100872- (2023)
Background & Aims: Alcohol-related liver disease (ALD) is a global healthcare challenge with limited treatment options. 24-Norursodeoxycholic acid (NorUDCA) is a synthetic bile acid with anti-inflammatory properties in experimental and human cholesta
Externí odkaz:
https://doaj.org/article/604fc6dffe2b445992c1e43edd5e7284
Autor:
Moris Sangineto, Christoph Grander, Felix Grabherr, Lisa Mayr, Barbara Enrich, Julian Schwärzler, Marcello Dallio, Vidyasagar Naik Bukke, Archana Moola, Antonio Moschetta, Timon E. Adolph, Carlo Sabbà, Gaetano Serviddio, Herbert Tilg
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Alcohol-related liver disease (ALD) is a major cause of liver disease and represents a global burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop alcoholic fatty liver disease (AFLD), only a minority evolves to steatohepat
Externí odkaz:
https://doaj.org/article/0ddb120444a241bca471377e37a98eb7
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 13 (2022)
Metabolic dysfunction–associated fatty liver disease (MAFLD) has appeared as the leading liver disease worldwide. Whereas the terminology nonalcoholic fatty liver disease (NAFLD) mainly reflected a negative selection and exclusion of alcohol-relate
Externí odkaz:
https://doaj.org/article/a0e13b3310624454922123155366466a
Autor:
Benedetta M. Motta, Christoph Grander, Martin Gögele, Luisa Foco, Vladimir Vukovic, Roberto Melotti, Christian Fuchsberger, Alessandro De Grandi, Chiara Cantaloni, Anne Picard, Deborah Mascalzoni, Alessandra Rossini, Cristian Pattaro, Herbert Tilg, Peter P. Pramstaller
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is characterized by triglyceride accumulation in the hepatocytes in the absence of alcohol overconsumption, commonly associated with insulin resistance and obesity. Both NAFLD and type 2 d
Externí odkaz:
https://doaj.org/article/4d21067acc604e838bac1618f6fa51dc
Autor:
Maria Effenberger, Andreas Kronbichler, Erica Bettac, Felix Grabherr, Christoph Grander, Timon Erik Adolph, Gert Mayer, Heinz Zoller, Paul Perco, Herbert Tilg
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 8, p e21656 (2021)
BackgroundLiver transplantation (LT) is the only curative treatment for end-stage liver disease. Less than 10% of global transplantation needs are met worldwide, and the need for LT is still increasing. The death rates on the waiting list remain too
Externí odkaz:
https://doaj.org/article/bf6552f29cfd42d28b886c920da27d11
Autor:
Heinz Zoller, Herbert Tilg, Maria Effenberger, Stefanie Seiwald, Gernot Fritsche, Rosa Bellmann-Weiler, Günter Weiss, Timon Erik Adolph, Christoph Grander, Frank Hartig, Sophie Wildner
Publikováno v:
BMJ Open Gastroenterology, Vol 7, Iss 1 (2020)
Objective Severe liver damage is associated with worse outcome in COVID-19. Our aim was to explore the degree of liver damage, liver stiffness (LS) and severity of illness in patients with COVID-19.Design We investigated 32 patients with COVID-19 adm
Externí odkaz:
https://doaj.org/article/24133199578a4ddb9aae688216171819
Autor:
Christoph Grander, Felix Grabherr, Ilaria Spadoni, Barbara Enrich, Georg Oberhuber, Maria Rescigno, Herbert Tilg
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
The translocation of bacterial components from the intestinal lumen into the portal circulation is crucial in the pathogenesis of alcoholic liver disease (ALD). Recently the important role of the gut vascular barrier (GVB) was elucidated in alcoholic
Externí odkaz:
https://doaj.org/article/1fa84735b7d442a98a16aa83ac56bde6
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Non-alcoholic fatty liver disease (NAFLD) has emerged as one of the leading liver diseases worldwide. NAFLD is characterized by hepatic steatosis and may progress to an inflammatory condition termed non-alcoholic steatohepatitis (NASH), liver cirrhos
Externí odkaz:
https://doaj.org/article/8235906e788b4ab2be356fb8b87ab529
Autor:
Julian Schwärzler, Lisa Mayr, Arnau Vich Vila, Felix Grabherr, Lukas Niederreiter, Maureen Philipp, Christoph Grander, Moritz Meyer, Almina Jukic, Simone Tröger, Barbara Enrich, Nicole Przysiecki, Markus Tschurtschenthaler, Felix Sommer, Irmgard Kronberger, Jakob Koch, Richard Hilbe, Michael W. Hess, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Nicole C. Kaneider, Verena Wieser, Markus A. Keller, Rinse K. Weersma, Konrad Aden, Philip Rosenstiel, Richard S. Blumberg, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Publikováno v:
Gastroenterology, 162(6), 1690-1704. W B SAUNDERS CO-ELSEVIER INC
BACKGROUND & AIMS: Crohn's disease (CD) globally emerges with Westernization of lifestyle and nutritional habits. However, a specific dietary constituent that comprehensively evokes gut inflammation in human IBD remains elusive. Here, we aimed at del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c726146105d04b2becffd9f02b053d
https://doi.org/10.1053/j.gastro.2022.01.004
https://doi.org/10.1053/j.gastro.2022.01.004
Adipocyte GPX4 protects against inflammation, hepatic insulin resistance and metabolic dysregulation
Autor:
Julian Schwärzler, Lisa Mayr, Bernhard Radlinger, Felix Grabherr, Maureen Philipp, Bernhard Texler, Christoph Grander, Andreas Ritsch, Monika Hunjadi, Barbara Enrich, Karin Salzmann, Qitao Ran, Lukas A. Huber, Herbert Tilg, Susanne Kaser, Timon E. Adolph
Publikováno v:
International Journal of Obesity. 46:951-959
Metabolic inflammation is a hallmark of obesity and related disorders, afflicting substantial morbidity and mortality to individuals worldwide. White visceral and subcutaneous adipose tissue not only serves as energy storage but also controls metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4689bc3056a6dab73009fb770b871473
https://doi.org/10.1038/s41366-022-01064-9
https://doi.org/10.1038/s41366-022-01064-9