Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Christoph, Gerlinger"'
Autor:
Charles S. Cleeland, Karen N. Keating, Brian Cuffel, Cem Elbi, Jonathan M. Siegel, Christoph Gerlinger, Tara Symonds, Jeff A. Sloan, Amylou C. Dueck, Andrew Bottomley, Xin Shelley Wang, Loretta A. Williams, Tito R. Mendoza
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract We developed a composite symptom score (CSS) representing disease-related symptom burden over time in patients with malignant pleural mesothelioma (MPM). Longitudinal data were collected from an open-label Phase IIB study in which 239 patien
Externí odkaz:
https://doaj.org/article/db2e23fb2d8d4a519dc6a1a356122e86
Publikováno v:
BMJ Open, Vol 13, Iss 7 (2023)
Objective The substitution of an in-study control population with a historical control (HC) population is considered a viable option for reducing the necessary recruitment of control patients. However, it is necessary to evaluate whether this method
Externí odkaz:
https://doaj.org/article/18038021e0d740cf913adca75382030c
Autor:
Gilda Schmidt, Sebastian Findeklee, Gerda del Sol Martinez, Mihai-Teodor Georgescu, Christoph Gerlinger, Sogand Nemat, Gilbert Georg Klamminger, Meletios P. Nigdelis, Erich-Franz Solomayer, Bashar Haj Hamoud
Publikováno v:
Diagnostics, Vol 13, Iss 17, p 2811 (2023)
Introduction: Nowadays chemotherapy in breast cancer patients is optionally applied neoadjuvant, which allows for testing of tumor response to the chemotherapeutical treatment in vivo, as well as allowing a greater number of patients to benefit from
Externí odkaz:
https://doaj.org/article/7b337aa3512c489789b947e91c415d4d
Autor:
Kerstin Becker, Klaas Heinemann, Bruno Imthurn, Lena Marions, Sabine Moehner, Christoph Gerlinger, Marco Serrani, Thomas Faustmann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Endometriosis is a chronic disease that requires a suitable, lifelong treatment. To our knowledge, the Visanne Post-approval Observational Study (VIPOS) is to date the largest real-world, non-interventional study investigating hormonal manag
Externí odkaz:
https://doaj.org/article/c778c0d9ca2547efa8d7bde6acf4c01a
Autor:
Helen Kitchen, Christian Seitz, Andrew Trigg, Natalie Aldhouse, Thomas Willgoss, Heinz Schmitz, Adam Gater, Christoph Gerlinger, Claudia Haberland
Publikováno v:
Health and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background The Endometriosis Symptom Diary (ESD) and Endometriosis Impact Scale (EIS) are patient-reported outcome measures developed to evaluate efficacy in clinical trials and clinical practice. The ESD is a daily electronic diary assessin
Externí odkaz:
https://doaj.org/article/537b055f2bf94c98b692418f1ba4bdc2
Autor:
Claudia Haberland, Anna Filonenko, Christian Seitz, Matthias Börner, Christoph Gerlinger, Helen Doll, Dorothea Wessiepe
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-13 (2020)
Abstract Background To evaluate the psychometric and measurement properties of two patient-reported outcome instruments, the menstrual pictogram superabsorbent polymer-containing version 3 (MP SAP-c v3) and Uterine Fibroid Daily Bleeding Diary (UF-DB
Externí odkaz:
https://doaj.org/article/4d23327c533c49fab32f606a63296cab
Publikováno v:
Drugs - Real World Outcomes, Vol 7, Iss 3, Pp 221-227 (2020)
Abstract Introduction For a new drug to be developed, the desired properties are described in a target product profile. Objective We propose a framework for using real-world data to measure the disease-specific costs of the current standard of care a
Externí odkaz:
https://doaj.org/article/0e95d10e90a84a2099e661056a94add0
Publikováno v:
BMC Women's Health, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Pictorial blood loss assessment charts (PBACs) represent the most widely used method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were to: (1) determine the diagnostic accuracy of PBACs that hav
Externí odkaz:
https://doaj.org/article/e48b5964ead0445a91c542341abe0e63
Autor:
Adam Gater, Fiona Taylor, Christian Seitz, Christoph Gerlinger, Kamonthip Wichmann, Claudia Haberland
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-17 (2020)
Abstract Background Endometriosis is a common, chronic, impactful condition in women of reproductive age. In the absence of established sensitive and specific biomarkers, disease severity is determined by patient-reported symptoms and impacts. This a
Externí odkaz:
https://doaj.org/article/596f7edae60a495abcc5645a93bfa82d
Autor:
Shona Kalkman, Menno Mostert, Christoph Gerlinger, Johannes J. M. van Delden, Ghislaine J. M. W. van Thiel
Publikováno v:
BMC Medical Ethics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Large-scale linkage of international clinical datasets could lead to unique insights into disease aetiology and facilitate treatment evaluation and drug development. Hereto, multi-stakeholder consortia are currently designing seve
Externí odkaz:
https://doaj.org/article/5e975769c50045aeafffbbb56736cbd8