Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christoph, Borek"'
Autor:
Lina Irsheid, Thomas Wehler, Christoph Borek, Werner Kiefer, Ruth Brenk, Maria Elena Ortiz-Soto, Jürgen Seibel, Tanja Schirmeister
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216132 (2019)
Golgi α-mannosidase II (GMII) is a glycoside hydrolase playing a crucial role in the N-glycosylation pathway. In various tumour cell lines, the distribution of N-linked sugars on the cell surface is modified and correlates with the progression of tu
Externí odkaz:
https://doaj.org/article/4c10653b62ac42bd84921c63fc111225
Autor:
Christoph Borek, Elmar Jaenicke, Josef Kehrein, Christoph A. Sotriffer, Ruth Brenk, Christian Kersten, Edmond Fleischer
Publikováno v:
Journal of Medicinal Chemistry
2095–2113
2095–2113
A model system of two related enzymes with conserved binding sites, namely N-myristoyltransferase from two different organisms, was studied to decipher the driving forces that lead to selective inhibition in such cases. Using a combination of computa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47394654afd000c6bea7b03106c7556f
https://doi.org/10.1021/acs.jmedchem.9b00586
https://doi.org/10.1021/acs.jmedchem.9b00586
Autor:
Christian, Kersten, Edmond, Fleischer, Josef, Kehrein, Christoph, Borek, Elmar, Jaenicke, Christoph, Sotriffer, Ruth, Brenk
Publikováno v:
Journal of medicinal chemistry. 63(5)
A model system of two related enzymes with conserved binding sites, namely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84ed6e1e52ec0e3753a394fba695bf73
https://pubmed.ncbi.nlm.nih.gov/31423787
https://pubmed.ncbi.nlm.nih.gov/31423787
Publikováno v:
Chembiochem
Ribonucleic acid (RNA) is central to many life processes and, to fulfill its function, it has a substantial chemical variety in its building blocks. Enzymatic thiolation of uridine introduces 4‐thiouridine (s4U) into many bacterial transfer RNAs (t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8ee9e2a4a6a53f6088662137bc4ecd
https://doi.org/10.1002/cbic.202000637
https://doi.org/10.1002/cbic.202000637