Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Christoph, Alexiou"'
Autor:
Chunguang Liang, Silvia Spoerl, Yin Xiao, Katharina M. Habenicht, Sigrun S. Haeusl, Isabel Sandner, Julia Winkler, Nicholas Strieder, Rüdiger Eder, Hanna Stanewsky, Christoph Alexiou, Diana Dudziak, Andreas Rosenwald, Matthias Edinger, Michael Rehli, Petra Hoffmann, Thomas H. Winkler, Friederike Berberich-Siebelt
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In clinical situations, peripheral blood accessible CD3+CD4+CXCR5+ T-follicular helper (TFH) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity of TFH cells
Externí odkaz:
https://doaj.org/article/7c0d3bc23f4c4d5f842af48b76085e66
Autor:
Felix Pfister, Jan Dörrie, Niels Schaft, Vera Buchele, Harald Unterweger, Lucas R. Carnell, Patrick Schreier, Rene Stein, Markéta Kubánková, Jochen Guck, Holger Hackstein, Christoph Alexiou, Christina Janko
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmunotherapy of cancer is an emerging field with the potential to improve long-term survival. Thus far, adoptive transfer of tumor-specific T cells represents an effective treatment option for tumors of the hematological system such as lym
Externí odkaz:
https://doaj.org/article/46cbcad70ccd47019395acaf9ee98ab1
Autor:
Adrian Holler, Iwona Cicha, Markus Eckstein, Marlen Haderlein, Marina Pöttler, Anja Rappl, Heinrich Iro, Christoph Alexiou
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 4743-4755 (2022)
Abstract Background Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone marrow involvement. EMPs are usually located in the head and neck region, but can also occur along the digest
Externí odkaz:
https://doaj.org/article/24f55930fe8d47d1a66ae26100b98e3e
Autor:
Patrick Vogel, Martin Andreas Rückert, Bernhard Friedrich, Rainer Tietze, Stefan Lyer, Thomas Kampf, Thomas Hennig, Lars Dölken, Christoph Alexiou, Volker Christian Behr
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Sensitive methods for antibody detection tend to be expensive and slow. Here, the authors report a magnetic particle spectroscopy method named COMPASS, as a rapid and low-cost technique which is comparable to ELISA in terms of sensitivity but with a
Externí odkaz:
https://doaj.org/article/dce94727e94b4459a9345b1fc92a61b3
Autor:
Hatice Genç, Bernhard Friedrich, Christoph Alexiou, Krzysztof Pietryga, Iwona Cicha, Timothy E. L. Douglas
Publikováno v:
Molecules, Vol 28, Iss 20, p 7052 (2023)
Background: Whey protein isolate (WPI) is a by-product from the dairy industry, whose main component is β-lactoglobulin. Upon heating, WPI forms a hydrogel which can both support controlled drug delivery and enhance the proliferation and osteogenic
Externí odkaz:
https://doaj.org/article/5454c12d92f5423695c2e56b4f229a14
Autor:
Sonia Sebastian, Manuela Klingler Hoffmann, Douglas Howard, Clifford Young, Jenni Washington, Harald Unterweger, Christoph Alexiou, Tyron Turnbull, Richard D’Andrea, Peter Hoffmann, Ivan Kempson
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1617 (2023)
Nanoparticle-based therapeutics are being clinically translated for treating cancer. Even when thought to be biocompatible, nanoparticles are being increasingly identified as altering cell regulation and homeostasis. Antioxidant pathways are importan
Externí odkaz:
https://doaj.org/article/23c1eca4df674843b58bdc8bd938d7cb
Autor:
Jonas Dinter, Ralf P. Friedrich, Hai Yang, Christian Pilarsky, Harald Mangge, Marina Pöttler, Christina Janko, Christoph Alexiou, Stefan Lyer
Publikováno v:
Materials, Vol 16, Iss 7, p 2906 (2023)
Pancreatic ductal adenocarcinoma is a hard-to-treat, deadly malignancy. Traditional treatments, such as surgery, radiation and chemotherapy, unfortunately are still not able to significantly improve long-term survival. Three-dimensional (3D) cell cul
Externí odkaz:
https://doaj.org/article/9ca91684016d4e029f99a14c4afb7a9c
Autor:
Rainer Tietze, Christoph Alexiou
Publikováno v:
Precision Nanomedicine, Vol 5, Iss 2 (2022)
Biomedical applications in medicine are an area of research studied in great breadth, covering the various potential applications. Mimicking natural processes promises to be a successful strategy for several reasons. For example, physiological struct
Externí odkaz:
https://doaj.org/article/8f5701e6d75647809e36837f1abeb0f1
Autor:
Lisa Zschiesche, Christina Janko, Bernhard Friedrich, Benjamin Frey, Julia Band, Stefan Lyer, Christoph Alexiou, Harald Unterweger
Publikováno v:
Nanomaterials, Vol 13, Iss 1, p 14 (2022)
Dextran-coated superparamagnetic iron oxide nanoparticles (SPIONDex) of various sizes can be used as contrast agents in magnetic resonance imaging (MRI) of different tissues, e.g., liver or atherosclerotic plaques, after intravenous injection. In pre
Externí odkaz:
https://doaj.org/article/c6f94bc98cf1404091b306afa49389d3
Autor:
Jessica Behr, Lucas R. Carnell, Rene Stein, Felix Pfister, Bernhard Friedrich, Christian Huber, Stefan Lyer, Julia Band, Eveline Schreiber, Christoph Alexiou, Christina Janko
Publikováno v:
Cancers, Vol 14, Iss 23, p 5978 (2022)
Superparamagnetic iron oxide nanoparticles (SPIONs) are used in nanomedicine as transporter systems for therapeutic cargos, or to magnetize cells to make them magnetically guidable. In cancer treatment, the site-directed delivery of chemotherapeutics
Externí odkaz:
https://doaj.org/article/8af6cf05cc5b4c9ebce7c61cfc8687bd