Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christoffer V. Sørensen"'
Autor:
Christoffer V. Sørensen, Julián Fernández, Anna Christina Adams, Helen H. K. Wildenauer, Sanne Schoffelen, Line Ledsgaard, Manuela B. Pucca, Michael Fiebig, Felipe A. Cerni, Tulika Tulika, Bjørn G. Voldborg, Aneesh Karatt-Vellatt, J. Preben Morth, Anne Ljungars, Lise M. Grav, Bruno Lomonte, Andreas H. Laustsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Improved therapies are needed against snakebite envenoming, which kills and permanently disables thousands of people each year. Recently developed neutralizing monoclonal antibodies against several snake toxins have shown promise in preclini
Externí odkaz:
https://doaj.org/article/99301d927d1f464bb9fbaf12412f986c
Autor:
Christoffer V. Sørensen, Line Ledsgaard, Helen H. K. Wildenauer, Camilla H. Dahl, Tasja W. Ebersole, Markus-Frederik Bohn, Anne Ljungars, Timothy P. Jenkins, Andreas H. Laustsen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Antibodies with cross-reactive binding and broad toxin-neutralizing capabilities are advantageous for treating indications such as infectious diseases and animal envenomings. Such antibodies have been successfully selected against closely re
Externí odkaz:
https://doaj.org/article/dc0f626d0f1e4380a0b1f8a7a0308d17
Autor:
Esperanza Rivera-de-Torre, Charlotte Rimbault, Timothy P. Jenkins, Christoffer V. Sørensen, Anna Damsbo, Natalie J. Saez, Yoan Duhoo, Celeste Menuet Hackney, Lars Ellgaard, Andreas H. Laustsen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Animal venoms are complex mixtures containing peptides and proteins known as toxins, which are responsible for the deleterious effect of envenomations. Across the animal Kingdom, toxin diversity is enormous, and the ability to understand the biochemi
Externí odkaz:
https://doaj.org/article/f5c57d7e144b4392a0dd1b529e5a9d43
Autor:
Sofie Føns, Line Ledsgaard, Maxim V. Nikolaev, Alexander A. Vassilevski, Christoffer V. Sørensen, Manon K. Chevalier, Michael Fiebig, Andreas H. Laustsen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Widow spiders are among the few spider species worldwide that can cause serious envenoming in humans. The clinical syndrome resulting from Latrodectus spp. envenoming is called latrodectism and characterized by pain (local or regional) associated wit
Externí odkaz:
https://doaj.org/article/e63ea812b8334c1392ff1e1a1f49c58d
Autor:
Manuela B. Pucca, Shirin Ahmadi, Felipe A. Cerni, Line Ledsgaard, Christoffer V. Sørensen, Farrell T. S. McGeoghan, Trenton Stewart, Erwin Schoof, Bruno Lomonte, Ulrich auf dem Keller, Eliane C. Arantes, Figen Çalışkan, Andreas H. Laustsen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Toxin synergism is a complex biochemical phenomenon, where different animal venom proteins interact either directly or indirectly to potentiate toxicity to a level that is above the sum of the toxicities of the individual toxins. This provides the an
Externí odkaz:
https://doaj.org/article/f708fbc151bd4462b01ad31680dc485f
Autor:
Manuela B. Pucca, Felipe A. Cerni, Isadora S. Oliveira, Timothy P. Jenkins, Lídia Argemí, Christoffer V. Sørensen, Shirin Ahmadi, José E. Barbosa, Andreas H. Laustsen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Honey bees can be found all around the world and fulfill key pollination roles within their natural ecosystems, as well as in agriculture. Most species are typically docile, and most interactions between humans and bees are unproblematic, despite the
Externí odkaz:
https://doaj.org/article/97dcfc3226464dc892b3abb22c6bed64
Autor:
Christoffer V. Sørensen, Cecilie Knudsen, Ulrich auf dem auf dem Keller, Konstantinos Kalogeropoulos, Cristina Gutiérrez-Jiménez, Manuela B. Pucca, Eliane C. Arantes, Karla C. F. Bordon, Andreas H. Laustsen
Publikováno v:
Toxins, Vol 12, Iss 4, p 240 (2020)
Antibiotics are often administered with antivenom following snakebite envenomings in order to avoid secondary bacterial infections. However, to this date, no studies have evaluated whether antibiotics may have undesirable potentiating effects on snak
Externí odkaz:
https://doaj.org/article/66fd5242d24c40cd89e3ffb2ae989b2c
Autor:
Konstantinos Kalogeropoulos, Markus-Frederik Bohn, David E. Jenkins, Jann Ledergerber, Christoffer V. Sørensen, Nils Hofmann, Jack Wade, Thomas Fryer, Giang Thi Tuyet Nguyen, Ullrich auf dem Keller, Andreas H. Laustsen, Timothy P. Jenkins
Protein structure determination is a critical aspect of biological research, enabling us to understand protein function and potential applications. Recent advances in deep learning and artificial intelligence have led to the development of several pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d860c3a46b2024e816bccff0335f8be
https://doi.org/10.1101/2023.05.05.539526
https://doi.org/10.1101/2023.05.05.539526
Autor:
Timothy P. Jenkins, William Michael Laprade, Andrés Sánchez, Tulika Tulika, Carol O’Brien, Christoffer V. Sørensen, Trenton K. Stewart, Thomas Fryer, Andreas H. Laustsen, José María Gutiérrez
Publikováno v:
Frontiers in Tropical Diseases
Venom-induced haemorrhage constitutes a severe pathology in snakebite envenomings, especially those inflicted by viperid species. To both explore venom activity accurately and evaluate the efficacy of viperid antivenoms for the neutralisation of haem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3a4cc284191a242623e72d3e40fa36
https://doi.org/10.3389/fitd.2022.1063640
https://doi.org/10.3389/fitd.2022.1063640
Autor:
Andreas Hougaard Laustsen, Manuela Berto Pucca, Christoffer V. Sørensen, Figen Caliskan, Rahel Janke, Line Ledsgaard, Erwin M. Schoof, Jonas A. Jürgensen, Shirin Ahmadi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Ahmadi, S, Pucca, M B, Jürgensen, J A, Janke, R, Ledsgaard, L, Schoof, E M, Sørensen, C V, Çalışkan, F & Laustsen, A H 2020, ' An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies ', Scientific Reports, vol. 10, no. 1, 10765 . https://doi.org/10.1038/s41598-020-67654-7
Scientific Reports
Ahmadi, S, Pucca, M B, Jürgensen, J A, Janke, R, Ledsgaard, L, Schoof, E M, Sørensen, C V, Çalışkan, F & Laustsen, A H 2020, ' An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies ', Scientific Reports, vol. 10, no. 1, 10765 . https://doi.org/10.1038/s41598-020-67654-7
Broadly-neutralizing monoclonal antibodies are of high therapeutic utility against infectious diseases caused by bacteria and viruses, as well as different types of intoxications. Snakebite envenoming is one such debilitating pathology, which is curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8566aa682938caaaa7b2a9f0ceb19b
http://link.springer.com/article/10.1038/s41598-020-67654-7
http://link.springer.com/article/10.1038/s41598-020-67654-7