Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Christoffer, Löf"'
Autor:
Konrad Patyra, Christoffer Löf, Holger Jaeschke, Hendrik Undeutsch, Huifei Sophia Zheng, Sofia Tyystjärvi, Kamila Puławska, Milena Doroszko, Marcin Chruściel, Britt-Marie Loo, Riikka Kurkijärvi, Fu-Ping Zhang, Chen-Che Jeff Huang, Claes Ohlsson, Andreina Kero, Matti Poutanen, Jorma Toppari, Ralf Paschke, Nafis Rahman, Ilpo Huhtaniemi, Jarmo Jääskeläinen, Jukka Kero
Publikováno v:
Thyroid
BACKGROUND: The human adrenal cortex undergoes several rapid remodeling steps during its lifetime. In rodents, similar remodeling occurs postnatally in the “X-zone” layer through unknown mechanisms. Furthermore, little is known regarding the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284899e225b5924087284d486b7020d1
https://doi.org/10.1089/thy.2021.0535
https://doi.org/10.1089/thy.2021.0535
Autor:
Gudrun Wahlström, Samuel Heron, Matias Knuuttila, Elina Kaikkonen, Nea Tulonen, Olli Metsälä, Christoffer Löf, Otto Ettala, Peter J Boström, Pekka Taimen, Matti Poutanen, Johanna Schleutker
Publikováno v:
Human Molecular Genetics. 31:2063-2077
Prostate cancer is among the most common cancers in men, with a large fraction of the individual risk attributable to heritable factors. A majority of the diagnosed cases does not lead to a lethal disease, and hence biological markers that can distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52866657a4b2d8993b6364a3310bfe
https://doi.org/10.1093/hmg/ddac012
https://doi.org/10.1093/hmg/ddac012
Autor:
Muhammad Yasir Asghar, Taru Lassila, Ilkka Paatero, Van Dien Nguyen, Pauliina Kronqvist, Jixi Zhang, Anna Slita, Christoffer Löf, You Zhou, Jessica Rosenholm, Kid Törnquist
Stromal interaction molecule 1 (STIM1) and the ORAI1 calcium channel mediate store-operated calcium entry (SOCE) and regulate a multitude of cellular functions. The identity and function of these proteins in thyroid cancer remained elusive. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7823b418169665dd8cadaf0ed11256dc
https://doi.org/10.21203/rs.3.rs-183367/v1
https://doi.org/10.21203/rs.3.rs-183367/v1
Autor:
Pauliina Kronqvist, Christoffer Löf, You Zhou, Ilkka Paatero, Jessica M. Rosenholm, Taru Lassila, Van Dien Nguyen, Jixi Zhang, Kid Törnquist, Anna Slita, Muhammad Yasir Asghar
Publikováno v:
Cellular and Molecular Life Sciences
Stromal interaction molecule 1 (STIM1) and the ORAI1 calcium channel mediate store-operated calcium entry (SOCE) and regulate a multitude of cellular functions. The identity and function of these proteins in thyroid cancer remain elusive. We show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61995a3bf0a8cddb9880321f94182881
https://pubmed.ncbi.nlm.nih.gov/34155535
https://pubmed.ncbi.nlm.nih.gov/34155535
Autor:
Konrad Patyra, Christoffer Löf, Holger Jaeschke, Hendrik Undeutsch, Huifei Zheng, Sofia Tyystjärvi, Kamila Puławska, Milena Doroszko, Marcin Chruściel, Britt-Marie Loo, Riikka Kurkijärvi, Fu-Ping Zhang, Jeff C.C. Huang, Claes Ohlsson, Andreina Kero, Matti Poutanen, Jorma Toppari, Ralf Paschke, Nafis Rahman, Ilpo Huhtaniemi, Jarmo Jääskeläinen, Jukka Kero
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8da977766100a2e833a0f6aa942197
https://doi.org/10.2139/ssrn.3912543
https://doi.org/10.2139/ssrn.3912543
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 32:241-256
The thyroid gland produces thyroid hormones (TH), which are essential regulators for growth, development and metabolism. The thyroid is mainly controlled by the thyroid-stimulating hormone (TSH) that binds to its receptor (TSHR) on thyrocytes and med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67735b8e63583c76a310c76b54aa5e2
https://doi.org/10.1016/j.beem.2018.03.007
https://doi.org/10.1016/j.beem.2018.03.007
Autor:
aaskelainen J, Erik Schoenmakers, Ilona Zvetkova, Sharone Barone, Ömer Tarım, Christoffer Löf, Liao Xh, Jukka Kero, Nadia Schoenmakers, Hakan Cangul, Eva Goncalves Serra, Eamonn R. Maher, Konrad Patyra, Panudda Srichomkwun, Kristien Boelaert, Halil Saglam, Frankl Fek, Adeline K Nicholas, Samuel Refetoff, ren E, Manoocher Soleimani, Hideyuki Iwayama, Carl A. Anderson, Williams Ed, Timothy Barrett, V. K. K. Chatterjee, Marja Ojaniemi
Publikováno v:
Yearbook of Paediatric Endocrinology.
Defects in genes mediating thyroid hormone biosynthesis result in dyshormonogenic congenital hypothyroidism (CH). Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show that goitrous hypothyroidis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9506838af7edba2b7760a75226d41c01
https://doi.org/10.1530/ey.16.3.11
https://doi.org/10.1530/ey.16.3.11
Autor:
Christoffer Löf, Diana M. Toivola, Kid Törnquist, Nils Bäck, Alberto Sanz, Eric Dufour, Helen M. Cooper, Jan B. Parys, Kati Kemppainen, Tomas Blom, Joel H. Nyström, K-L Lin, Ilari Pulli, Taru Lassila, Muhammad Yasir Asghar
Sphingosine kinase 1 (SK1) converts sphingosine to the bioactive lipid sphingosine 1-phosphate (S1P). S1P binds to G-protein-coupled receptors (S1PR1-5) to regulate cellular events, including Ca2+ signaling. The SK1/S1P axis and Ca2+ signaling both p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e967739d2eec0877d4cc44e44873b7
https://lirias.kuleuven.be/handle/123456789/640567
https://lirias.kuleuven.be/handle/123456789/640567
Autor:
Ralf Paschke, Fu-Ping Zhang, Christoffer Löf, Holger Jaeschke, Jukka Kero, Matti Poutanen, Jorma Toppari, Meeri Jannari, Kristiina Makkonen, Henriette Undeutsch, Moosa Khalil, Konrad Patyra, Markus Eszlinger
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 28(10)
Constitutively active thyrotropin receptor (TSHR) mutations are the most common etiology of non-autoimmune hyperthyroidism (NAH). Thus far, the functionality of these mutations has been tested in vitro, but the in vivo models are lacking.To understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e272cef38dc54402eff8bb958b3b0d
https://pubmed.ncbi.nlm.nih.gov/30132406
https://pubmed.ncbi.nlm.nih.gov/30132406
Autor:
Konrad, Patyra, Holger, Jaeschke, Christoffer, Löf, Meeri, Jännäri, Suvi T, Ruohonen, Henriette, Undeutsch, Moosa, Khalil, Andreina, Kero, Matti, Poutanen, Jorma, Toppari, Min, Chen, Lee S, Weinstein, Ralf, Paschke, Jukka, Kero
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Thyroid function is controlled by thyroid-stimulating hormone (TSH), which binds to its G protein-coupled receptor [thyroid-stimulating hormone receptor (TSHR)] on thyrocytes. TSHR can potentially couple to all G protein families, but it mainly activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad08e5853b1a9b8582e0ca9763263be1
https://pubmed.ncbi.nlm.nih.gov/29799790
https://pubmed.ncbi.nlm.nih.gov/29799790