Untargeted blood serum proteomics identifies novel proteins related to neurological recovery after human spinal cord injury

Autor: Daniel Garcia-Ovejero, Evelyn Beyerer, Orpheus Mach, Iris Leister, Martin Strowitzki, Christof Wutte, Doris Maier, John LK Kramer, Ludwig Aigner, Angel Arevalo-Martin, Lukas Grassner

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)

Abstract Background The discovery of new prognostic biomarkers following spinal cord injury (SCI) is a rapidly growing field that could help uncover the underlying pathological mechanisms of SCI and aid in the development of new therapies. To date, t

Externí odkaz: https://doaj.org/article/774e8d415fbb4a3a8581b08cc9251e7a

A New Score Based on the International Standards for Neurological Classification of Spinal Cord Injury for Integrative Evaluation of Changes in Sensorimotor Functions

Autor: Lukas Grassner, Daniel Garcia-Ovejero, Orpheus Mach, Elisa Lopez-Dolado, Eduardo Vargas-Baquero, Monica Alcobendas-Maestro, Ana Esclarin, Ludwig Sanktjohaneser, Christof Wutte, Johannes Becker, Sara Lener, Sebastian Hartmann, Pierre-Pascal Girod, Nikolaus Kögl, Christoph J. Griessenauer, Marios Papadopoulus, Fred Geisler, Claudius Thome, Eduardo Molina-Holgado, Joan Vidal, Armin Curt, Giorgio Scivoletto, James Guest, Doris Maier, Norbert Weidner, Rüdiger Rupp, John L.K. Kramer, Angel Arevalo-Martin

Publikováno v: Journal of Neurotrauma
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Sensorimotor function of patients with spinal cord injury (SCI) is commonly assessed according to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI). From the ISNCSCI segmental motor and sensory assessments, u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23008b80a1af6c0c8239180a0ef0d321
https://doi.org/10.1089/neu.2021.0368

Early Decompression (<8 Hours) Improves Functional Bladder Outcome and Mobility After Traumatic Thoracic Spinal Cord Injury

Autor: Orpheus Mach, Lukas Grassner, Fabian Maria Stuby, Barbara Klein, Christof Wutte, Doris Maier, Johannes Becker, Martin Strowitzki, Claudius Thomé, Stephanie Panzer

Publikováno v: World Neurosurgery. 134:e847-e854

There is accumulating evidence of a potential beneficial effect of early surgical intervention after acute cervical spinal cord injury (SCI). However, around one third of all SCIs affect the thoracic spine. This cohort has not been extensively invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61423f794ddf634539c7200556064702
https://doi.org/10.1016/j.wneu.2019.11.015

Early Decompression (< 8 h) after Traumatic Cervical Spinal Cord Injury Improves Functional Outcome as Assessed by Spinal Cord Independence Measure after One Year

Autor: Stephanie Panzer, Volker Bühren, Jan Vastmans, Lukas Grassner, Orpheus Mach, Matthias Vogel, Doris Maier, Martin Strowitzki, Christof Wutte, Silvie Riesner, Barbara Klein

Publikováno v: Journal of Neurotrauma. 33:1658-1666

There is an ongoing controversy about the optimal timing for surgical decompression after acute traumatic cervical spinal cord injury (SCI). For this reason, we performed a retrospective study of patients who were operated on after traumatic cervical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48e861ff0949ee59c8dff305fb846ce
https://doi.org/10.1089/neu.2015.4325

Earlier Decompression (8 Hours) Results in Better Neurological and Functional Outcome after Traumatic Thoracolumbar Spinal Cord Injury

Autor: Lukas Grassner, Christof Wutte, Stephanie Panzer, Barbara Klein, Martin Strowitzki, Orpheus Mach, Johannes Becker, Doris Maier

Publikováno v: Journal of neurotrauma. 36(12)

The optimal timing of surgical intervention following spinal cord injury (SCI) remains under debate. Recent studies indicate a potential neurological and functional benefit of early surgery (8 h) after cervical SCI. For thoracolumbar SCI syndromes, f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200d01e44c9db6f0aa6532f90b5d6ff1
https://pubmed.ncbi.nlm.nih.gov/30489193