Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Christof, Seidl"'
Autor:
Benedikt Feuerecker, Andrei Gafita, Thomas Langbein, Robert Tauber, Christof Seidl, Frank Bruchertseifer, Jürgen E. Gschwendt, Wolfgang A. Weber, Calogero D’Alessandria, Alfred Morgenstern, Matthias Eiber
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16845 (2023)
Most Prostate Specific Membrane Antigens (PSMAs) targeting small molecules accumulate in the salivary glands (SGs), raising concerns about SG toxicity, especially after repeated therapies or therapy with 225Ac-labeled ligands. SG toxicity is assessed
Externí odkaz:
https://doaj.org/article/8679634db1754150a73ed6bafa3890e2
Autor:
Benedikt Feuerecker, Philipp Biechl, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Markus Schwaiger, Wolfgang Eisenreich
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Evaluation of treatment response is among the major challenges in modern oncology. We herein used a monoclonal antibody targeting the EGF receptor (EGFR) labelled with the alpha emitter 213Bi (213Bi-anti-EGFR-MAb). EJ28Luc (bladder) and LN18
Externí odkaz:
https://doaj.org/article/fc81492bf3d1462796b1f5eda86be014
Autor:
Zhoulei Li, Peng He, Yali Long, Gang Yuan, Wanqing Shen, Zhifeng Chen, Bing Zhang, Yue Wang, Dianchao Yue, Christof Seidl, Xiangsong Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The effective and economical therapeutic strategy for metastatic castration-resistant prostate cancer (mCRPC) is still requested from patients, who are not available for Lu-177 or Ra-223 treatment. Drug repurposing as a cost-effective and time-saving
Externí odkaz:
https://doaj.org/article/778b95a046684538907c9bb0edc7d852
Autor:
Weiwei Gong, Yueyang Liu, Christof Seidl, Eleftherios P. Diamandis, Marion Kiechle, Enken Drecoll, Matthias Kotzsch, Viktor Magdolen, Julia Dorn
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background In ovarian cancer, dysregulation of mRNA expression of several components of the family of the kallikrein-related peptidases (KLKs) is observed. In this study, we have analyzed the KLK5 mRNA expression pattern in tumor tissue of p
Externí odkaz:
https://doaj.org/article/a33ba9ca6f6a46c78588592b441d9223
Autor:
Zhoulei Li, Peng He, Ganhua Luo, Xinchong Shi, Gang Yuan, Bing Zhang, Christof Seidl, Andreas Gewies, Yue Wang, Yuan Zou, Yali Long, Dianchao Yue, Xiangsong Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundThe anticancer potential of pharmacologic ascorbic acid (AA) has been detected in a number of cancer cells. However, in vivo study suggested a strongly reduced cytotoxic activity of AA. It was known that pH could be a critical influencing f
Externí odkaz:
https://doaj.org/article/528290a21ac34e5381f5c3de3c9361d1
Autor:
Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester, Johannes Notni
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Background The recently growing interest in targeted alpha-therapy (TAT) calls for improvement of the labelling chemistry of the corresponding radionuclides. 213BiIII is a short-lived alpha emitter which emits only one alpha particle in its
Externí odkaz:
https://doaj.org/article/495a2c35be444e1fa1e84e696a4d206b
Autor:
Weiwei Gong, Yueyang Liu, Christof Seidl, Tobias Dreyer, Enken Drecoll, Matthias Kotzsch, Holger Bronger, Julia Dorn, Viktor Magdolen
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212968 (2019)
Overexpression of several members of the kallikrein-related peptidase (KLK) family, including KLK4, has been reported in ovarian cancer tissue, consistent with the fact that elevated levels of KLK protein are often also found in serum and in effusion
Externí odkaz:
https://doaj.org/article/fd32636242e84c4dacce1148406827ad
Autor:
Matthias Heck, Alfred Morgenstern, Anja Pickhard, Calogero D'Alessandria, Matthias Eiber, Andrei Gafita, Jürgen E. Gschwend, Karina Knorr, Wolfgang A. Weber, Benedikt Feuerecker, Ali Beheshti, Christof Seidl, Robert Tauber, Clemens Kratochwil, Margitta Retz, Frank Bruchertseifer
Publikováno v:
European Urology. 79:343-350
Background Beta-emitting Lu-177-labeled prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) is a new option for metastatic castration-resistant prostate cancer (mCRPC), but its antitumor effect can decrease over time. Objective To rep
Publikováno v:
Leukemia & Lymphoma. 62:630-639
Acute myeloid leukemia (AML) is a malignant disease of the bone marrow, comprising various subtypes. We have investigated seven different AML cell lines that showed different sensitivities toward the inducer of apoptosis ABT-737, with IC50 concentrat
Autor:
Antonia Richter, Wolfgang A. Weber, Adam Smith, David J. Donnelly, Katja Steiger, Dario Gosmann, Dasa Lipovsek, David Leung, Christof Seidl, Wendy Hayes, Christina Aulehner, Daniel Cohen, Angela M. Krackhardt, Stephanie Robu, Paul E. Morin, Samuel J. Bonacorsi
Publikováno v:
J Nucl Med
Blocking the interaction of the immune checkpoint molecule programmed cell death protein-1 and its ligand, PD-L1, using specific antibodies has been a major breakthrough for immune oncology. Whole-body PD-L1 expression PET imaging may potentially all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576026cd3c23166537b70b8c78e231b7
https://europepmc.org/articles/PMC8882891/
https://europepmc.org/articles/PMC8882891/