Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Christof, Regl"'
Autor:
Katharina Böttinger, Christof Regl, Veronika Schäpertöns, Erdmann Rapp, Therese Wohlschlager, Christian G. Huber
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 10, Pp 100982- (2024)
Glycans associated with biopharmaceutical drugs play crucial roles in drug safety and efficacy, and therefore, their reliable detection and quantification is essential. Our study introduces a multi-level quantification approach for glycosylation anal
Externí odkaz:
https://doaj.org/article/20e977f3b5274a2b8fd2ccb8448343ed
Autor:
Theresa Neuper, Tobias Frauenlob, Hieu-Hoa Dang, Peter W. Krenn, Gernot Posselt, Christof Regl, Nikolaus Fortelny, Veronika Schäpertöns, Michael S. Unger, Gunda Üblagger, Daniel Neureiter, Iris Mühlbacher, Michael Weitzendorfer, Franz Singhartinger, Klaus Emmanuel, Christian G. Huber, Silja Wessler, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Sophisticated immune evasion strategies enable Helicobacter pylori (H. pylori) to colonize the gastric mucosa of approximately half of the world’s population. Persistent infection and the resulting chronic inflammation are a major cause of gastric
Externí odkaz:
https://doaj.org/article/71409594e0d44f3793c2a852288917da
Autor:
Tobias Frauenlob, Theresa Neuper, Christof Regl, Veronika Schaepertoens, Michael S. Unger, Anna-Lena Oswald, Hieu-Hoa Dang, Christian G. Huber, Fritz Aberger, Silja Wessler, Jutta Horejs-Hoeck
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Helicobacter pylori is a widespread Gram-negative pathogen involved in a variety of gastrointestinal diseases, including gastritis, ulceration, mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. Immune responses aimed at eradicatio
Externí odkaz:
https://doaj.org/article/cb89368a84c4480bafb6c997f752a220
Autor:
Arthur Hinterholzer, Jennifer Moises, Christof Regl, Sebastian Schwap, Erdmann Rapp, Christian G. Huber, Mario Schubert
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The α-Gal epitope consisting of the terminal trisaccharide Galα1,3Galβ1,4GlcNAc exposed on cell or protein surfaces can cause severe immune reactions, such as hypersensitivity reactions, in humans. This epitope is also called the xenotransplantati
Externí odkaz:
https://doaj.org/article/d2a62006075448058a90ce5647d9d10a
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241560 (2020)
The monoclonal anti-CD20 IgG1 antibody rituximab is used as a first-line treatment for B cell lymphoma. Like all therapeutic antibodies, it is a complex protein for which both safety and efficacy heavily depend on the integrity of its three-dimension
Externí odkaz:
https://doaj.org/article/47425c7a97614d9db68607927bab00cb
Autor:
Fausto Gueths Gomes, André Cronemberger Andrade, Martin Wolf, Sarah Hochmann, Linda Krisch, Nicole Maeding, Christof Regl, Rodolphe Poupardin, Patricia Ebner-Peking, Christian G. Huber, Nicole Meisner-Kober, Katharina Schallmoser, Dirk Strunk
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 238 (2022)
Platelet-rich plasma is a promising regenerative therapeutic with controversial efficacy. We and others have previously demonstrated regenerative functions of human platelet lysate (HPL) as an alternative platelet-derived product. Here we separated e
Externí odkaz:
https://doaj.org/article/66abe7b053874210ab31375db1164318
Autor:
Laura Urwanisch, Michael Stefan Unger, Helene Sieberer, Hieu-Hoa Dang, Theresa Neuper, Christof Regl, Julia Vetter, Susanne Schaller, Stephan M. Winkler, Emanuela Kerschbamer, Christian X. Weichenberger, Peter W. Krenn, Michela Luciano, Lisa Pleyer, Richard Greil, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Cancers; Volume 15; Issue 4; Pages: 1039
Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by altered myeloid progenitor cell proliferation and differentiation. As in many other cancers, epigenetic transcriptional repressors such as histone deacetylases (HDACs) are dy
Autor:
Michael Hauser, Christof Regl, Werner Auzinger, Danila Zennaro, Peter Lackner, Sabrina Wildner, Christian G. Huber, Eva Vejvar, Sara Huber, Gabriele Gadermaier, Nicole Wopfer, Ronald van Ree, Josef Laimer, Martina Di Muzio, Adriano Mari, Fatima Ferreira, Mario Schubert
Publikováno v:
J Biol Chem
Journal of biological chemistry, 295(51), 17398-17410. American Society for Biochemistry and Molecular Biology Inc.
Journal of biological chemistry, 295(51), 17398-17410. American Society for Biochemistry and Molecular Biology Inc.
Identification of antibody-binding epitopes is crucial to understand immunological mechanisms. It is of particular interest for allergenic proteins with high cross-reactivity as observed in the lipid transfer protein (LTP) syndrome, which is characte
Autor:
Carmen M Abfalter, Esther Schönauer, Karthe Ponnuraj, Markus Huemer, Gabriele Gadermaier, Christof Regl, Peter Briza, Fatima Ferreira, Christian G Huber, Hans Brandstetter, Gernot Posselt, Silja Wessler
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162433 (2016)
Bacterial collagenases differ considerably in their structure and functions. The collagenases ColH and ColG from Clostridium histolyticum and ColA expressed by Clostridium perfringens are well-characterized collagenases that cleave triple-helical col
Externí odkaz:
https://doaj.org/article/a4bf99ba3d4d4efda636c41346dabb56
Autor:
Michael R. Sperling, Thomas Berger, Oliver J. Schmitz, Christof Regl, Werner Engewald, Katja Dettmer-Wilde, Christian G. Huber, Martin Vogel, Sebastian K. Piendl, Detlev Belder, Frank-Michael Matysik
Publikováno v:
Nachrichten aus der Chemie. 68:48-53