Conserved mechanisms of tumorigenesis in the Drosophila adult midgut.

Autor: Òscar Martorell, Anna Merlos-Suárez, Kyra Campbell, Francisco M Barriga, Christo P Christov, Irene Miguel-Aliaga, Eduard Batlle, Jordi Casanova, Andreu Casali

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88413 (2014)

Whereas the series of genetic events leading to colorectal cancer (CRC) have been well established, the precise functions that these alterations play in tumor progression and how they disrupt intestinal homeostasis remain poorly characterized. Activa

Externí odkaz: https://doaj.org/article/09543f861e1840338d2c3672816bc0e2

Kinetic Studies on the 2-Oxoglutarate/Fe(II)-Dependent Nucleic Acid Modifying Enzymes from the AlkB and TET Families

Autor: Zhiyuan Peng, Jian Ma, Christo Z. Christov, Tatyana Karabencheva-Christova, Nicolai Lehnert, Deyu Li

Publikováno v: DNA, Vol 3, Iss 2, Pp 65-84 (2023)

Nucleic acid methylations are important genetic and epigenetic biomarkers. The formation and removal of these markers is related to either methylation or demethylation. In this review, we focus on the demethylation or oxidative modification that is m

Externí odkaz: https://doaj.org/article/6e2dcc41816c436d9d5519cf999c94e0

Conformational effects on the circular dichroism of Human Carbonic Anhydrase II: a multilevel computational study.

Autor: Tatyana G Karabencheva-Christova, Uno Carlsson, Kia Balali-Mood, Gary W Black, Christo Z Christov

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56874 (2013)

Circular Dichroism (CD) spectroscopy is a powerful method for investigating conformational changes in proteins and therefore has numerous applications in structural and molecular biology. Here a computational investigation of the CD spectrum of the H

Externí odkaz: https://doaj.org/article/158ec676447147ad9e2e9d9d07cb82e8

Neuronal Control of Metabolism through Nutrient-Dependent Modulation of Tracheal Branching

Autor: Gerit A. Linneweber, Tomoki Otani, Bruno Hudry, Michaela Yuan, Elisabeth Knust, Irene Miguel-Aliaga, Mario de Bono, Jake Jacobson, Dirk Dormann, Christo P. Christov, Karl Emanuel Busch

Publikováno v: Cell
Linneweber, G A, Jacobson, J, Busch, K E, Hudry, B, Christov, C P, Dormann, D, Yuan, M, Otani, T, Knust, E, de Bono, M & Miguel-Aliaga, I 2014, ' Neuronal Control of Metabolism through Nutrient-Dependent Modulation of Tracheal Branching ', Cell, vol. 156, no. 1-2, pp. 69-83 . https://doi.org/10.1016/j.cell.2013.12.008

Summary During adaptive angiogenesis, a key process in the etiology and treatment of cancer and obesity, the vasculature changes to meet the metabolic needs of its target tissues. Although the cues governing vascular remodeling are not fully understo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cfb318d18d56c04d88034f4c76b1b2
http://europepmc.org/articles/PMC3898607

Conserved Mechanisms of Tumorigenesis in the Drosophila Adult Midgut

Autor: Christo P. Christov, Kyra Campbell, Irene Miguel-Aliaga, Anna Merlos-Suárez, Jordi Casanova, Eduard Batlle, Francisco M. Barriga, Andreu Casali, Òscar Martorell

Publikováno v: PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 9, Iss 2, p e88413 (2014)

Whereas the series of genetic events leading to colorectal cancer (CRC) have been well established, the precise functions that these alterations play in tumor progression and how they disrupt intestinal homeostasis remain poorly characterized. Activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d932422798bbaf59a53edb428839d4