Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christine van de Werken"'
Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse.
Autor:
Federica Federici, Aristea Magaraki, Evelyne Wassenaar, Catherina J H van Veen-Buurman, Christine van de Werken, Esther B Baart, Joop S E Laven, J Anton Grootegoed, Joost Gribnau, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006358 (2016)
In mouse female preimplantation embryos, the paternal X chromosome (Xp) is silenced by imprinted X chromosome inactivation (iXCI). This requires production of the noncoding Xist RNA in cis, from the Xp. The Xist locus on the maternally inherited X ch
Externí odkaz:
https://doaj.org/article/9d08fb3963e04fdaa5e1f586a9987f9d
Autor:
Margarida Avo Santos, Joop S.E. Laven, Joyce Schuilwerve, Holger Jahr, Esther B. Baart, Christine van de Werken, Cindy Eleveld
Publikováno v:
Chromosome Research, 21(5), 475-489. Springer Netherlands
Immunofluorescence has been widely used to study histone modification dynamics and chromosome-associated proteins that regulate the segregation of chromosomes during cell divisions. Since many of these regulatory proteins interact (in)directly to exe
Autor:
Catherina J. H. van Veen-Buurman, Esther B. Baart, Joost Gribnau, Federica Federici, Joop S.E. Laven, Willy M. Baarends, Evelyne Wassenaar, Christine van de Werken, J. Anton Grootegoed, Aristea Magaraki
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 10, p e1006358 (2016)
PLoS Genetics (online), 12(10). Public Library of Science
PLoS Genetics, Vol 12, Iss 10, p e1006358 (2016)
PLoS Genetics (online), 12(10). Public Library of Science
In mouse female preimplantation embryos, the paternal X chromosome (Xp) is silenced by imprinted X chromosome inactivation (iXCI). This requires production of the noncoding Xist RNA in cis, from the Xp. The Xist locus on the maternally inherited X ch
Autor:
Joop S.E. Laven, Bart C.J.M. Fauser, Christine van de Werken, Marieke de Vries, Esther B. Baart, Martijn J.M. Vromans, Geert J. P. L. Kops, Holger Jahr, Margarida Avo Santos, Susanne M.A. Lens
Publikováno v:
Human Reproduction, 26(7), 1868-1881. Oxford University Press
background: Human embryos generated by IVF demonstrate a high incidence of chromosomal segregation errors during the cleavage divisions. To analyse underlying molecular mechanisms, we investigated the behaviour of the chromosomal passenger complex (C
Autor:
Godfried W. van der Heijden, Antoine H.F.M. Peters, Mareike Albert, Cindy Eleveld, Willy M. Baarends, Joop S.E. Laven, Esther B. Baart, Christine van de Werken, Miriam Teeuwssen
Publikováno v:
Nature Communications
Nature Communications, 5. Nature Publishing Group
Nature Communications, 5. Nature Publishing Group
The different configurations of maternal and paternal chromatin, acquired during oogenesis and spermatogenesis, have to be rearranged after fertilization to form a functional embryonic genome. In the paternal genome, nucleosomal chromatin domains are