Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Christine Yee"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103234- (2024)
Summary: To improve human hepatotoxicity prediction, in vitro liver cell models replicating hepatocyte function, drug metabolism, and toxicity are required. Here, we present a protocol for creating 3D primary human hepatocyte (PHH) cell models using
Externí odkaz:
https://doaj.org/article/f4b054c43be74ff989bf3d1b7c2999b8
Autor:
Wanqi Zheng, Christine Yee Yan Wai, Jason Ka Chun Sit, Nam Sze Cheng, Christy Wing Man Leung, Ting Fan Leung
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1549 (2024)
Wheat, a component of the staple diet globally, is a common food allergen in children. The symptoms of wheat allergy (WA) range from skin rash to shortness of breath, significantly impairing quality of life. Following initial clinical suspicion, indi
Externí odkaz:
https://doaj.org/article/6258c2db4c3640f29bee844014ddd909
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Computational models are becoming an increasingly valuable tool in biomedical research. Their accuracy and effectiveness, however, rely on the identification of suitable parameters and on appropriate validation of the in-silico framework. Bo
Externí odkaz:
https://doaj.org/article/50822db79430477eacddde8895c5be7e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8f914bb34788406db3e8078be3b37769
Publikováno v:
Genes, Vol 14, Iss 12, p 2145 (2023)
Allergy to shellfishes, including mollusks and crustaceans, is a growing health concern worldwide. Crustacean shellfish is one of the “Big Eight” allergens designated by the U.S. Food and Drug Administration and is the major cause of food-induced
Externí odkaz:
https://doaj.org/article/108b3340f9734845bb09666df5e8a870
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Ovarian cancer has the highest mortality of all of the gynecological malignancies. There are several distinct histotypes of this malignancy characterized by specific molecular events and clinical behavior. These histotypes have differing responses to
Externí odkaz:
https://doaj.org/article/fd07eb882e41412ba1c79183458a253e
Autor:
Tao Xie, Kristie-Ann Dickson, Christine Yee, Yue Ma, Caroline E. Ford, Nikola A. Bowden, Deborah J. Marsh
Publikováno v:
Cancers, Vol 14, Iss 19, p 4621 (2022)
The advent of molecular targeted therapies has made a significant impact on survival of women with ovarian cancer who have defects in homologous recombination repair (HRR). High-grade serous ovarian cancer (HGSOC) is the most common histological subt
Externí odkaz:
https://doaj.org/article/7eabc083d47a427390ae94369354b83f
Publikováno v:
Molecules, Vol 27, Iss 3, p 727 (2022)
A diet-induced non-alcoholic fatty liver disease (NAFLD) model causing obesity in rodents was used to examine whether sitagliptin and gliclazide therapies have similar protective effects on pathological liver change. Methods: Male mice were fed a hig
Externí odkaz:
https://doaj.org/article/e55ade62bcc44c508a14b5a414d655f4
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13639 (2021)
(1) Background: studies on the long-term dynamic changes in fat depot metabolism in response to a high-fat diet (HFD) on hepatic lipid deposition and insulin resistance are sparse. This study investigated the dynamic changes produced by HFD and the p
Externí odkaz:
https://doaj.org/article/272ebc43445e421e82a420a90ccc8bf6
Autor:
Christine Yee, Nathan M Main, Alexandra Terry, Igor Stevanovski, Annette Maczurek, Alison J Morgan, Sarah Calabro, Alison J Potter, Tina L Iemma, David G Bowen, Golo Ahlenstiel, Fiona J Warner, Geoffrey W McCaughan, Susan V McLennan, Nicholas A Shackel
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0215557 (2019)
BackgroundChronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly m
Externí odkaz:
https://doaj.org/article/d0940ab7fa584a72b7bc28e44329defd