Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christine Wolak"'
Autor:
Brent W Anderson, Kuanqing Liu, Christine Wolak, Katarzyna Dubiel, Fukang She, Kenneth A Satyshur, James L Keck, Jue D Wang
Publikováno v:
eLife, Vol 8 (2019)
The alarmone (p)ppGpp regulates diverse targets, yet its target specificity and evolution remain poorly understood. Here, we elucidate the mechanism by which basal (p)ppGpp inhibits the purine salvage enzyme HPRT by sharing a conserved motif with its
Externí odkaz:
https://doaj.org/article/a0342011588d4272a5a29fd9a4d5eaf5
Autor:
James L. Keck, Nicolas Soubry, Rodrigo Reyes-Lamothe, Steven J. Sandler, Christine Wolak, Hui Jun Ma
Publikováno v:
Mol Microbiol
DNA replication complexes (replisomes) routinely encounter proteins and unusual nucleic acid structures that can impede their progress. Barriers can include transcription complexes and R-loops that form when RNA hybridizes with complementary DNA temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cba16bca5e77993107d6c3b952d730
https://europepmc.org/articles/PMC7934204/
https://europepmc.org/articles/PMC7934204/
Autor:
James L. Keck, Christine Wolak, Brent W. Anderson, Kenneth A. Satyshur, Kuanqing Liu, Katarzyna Dubiel, Jue D. Wang, Fukang She
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The alarmone (p)ppGpp regulates diverse targets, yet its target specificity and evolution remain poorly understood. Here, we elucidate the mechanism by which basal (p)ppGpp inhibits the purine salvage enzyme HPRT by sharing a conserved motif with its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4fe145f29cd47da63135ce5d20e1822
http://europepmc.org/articles/PMC6783271
http://europepmc.org/articles/PMC6783271
Autor:
Katarzyna Dubiel, Kenneth A. Satyshur, Kuanqing Liu, Christine Wolak, Brent W. Anderson, James L. Keck, Jue D. Wang
The signaling ligand (p)ppGpp binds diverse targets across bacteria, yet the mechanistic and evolutionary basis underlying these ligand-protein interactions remains poorly understood. Here we identify a novel (p)ppGpp binding motif in the enzyme HPRT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cc75f235f65da0927e2af45651ccaa
https://doi.org/10.1101/621474
https://doi.org/10.1101/621474
Publikováno v:
Cell, 177(1), 24-25. Cell Press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc00c73eedecb3ceb9d8af052465de6
https://hdl.handle.net/1765/116275
https://hdl.handle.net/1765/116275