Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christine Vaculik"'
Autor:
Christopher Schuster, Michael Mildner, Christian Fiala, Adelheid Elbe-Bürger, Marion Prior, Christine Vaculik, Georg Stingl, Wolfgang Eppel
Publikováno v:
The Journal of Investigative Dermatology
The adult human skin harbors a variety of leukocytes providing immune surveillance and host defense, but knowledge about their ontogeny is scarce. In this study we investigated the number and phenotype of leukocytes in prenatal human skin (dermal den
Autor:
Florian Göbel, Adelheid Elbe-Bürger, Christine Vaculik, Sabine Taschner, Jennifer Jurkin, Sabine Konradi, Susanne Richter, Herbert Strobl, Christina Mühlbacher, Doris Kneidinger, Christian Bieglmayer
Publikováno v:
Blood. 114:3813-3821
Two major pathways of human myeloid dendritic cell (DC) subset differentiation have previously been delineated. Langerhans cells (LCs) reside in epithelia in the steady state, whereas monocytes can provide dendritic cells (DCs) on demand in response
Autor:
Adelheid Elbe-Bürger, Christine Vaculik, Johnnie Akgün, Gero Kramer, Simone Meindl, Marion Prior, Georg Stingl, Anton Stuetz, Josef G. Meingassner
Publikováno v:
Journal of Investigative Dermatology. 129(9):2184-2192
Atopic dermatitis arises primarily in early infancy. In these patients, corticosteroids are used especially with great caution because of their side effects. Calcineurin inhibitors such as pimecrolimus (PIM) could be useful, but safety concerns have
Autor:
Christopher Schuster, Georg Stingl, Wolfgang Eppel, Adelheid Elbe-Bürger, Christine Vaculik, Oliver Brandt, Martin Imhof, Christian Fiala, Simone Meindl
Publikováno v:
The Journal of Experimental Medicine
Adequate numbers and functional maturity are needed for leukocytes to exhibit a protective role in host defense. During intrauterine life, the skin immune system has to acquire these prerequisites to protect the newborn from infection in the hostile
Autor:
Jianzhu Chen, Christine Vaculik, Genya Yanagida, Wolfgang Wadsak, Beate M. Rüger, Martha M. Eibl, Michael C. Carroll, Michael B. Fischer, Udo Losert, Alexander Becherer
Publikováno v:
European Journal of Immunology. 37:2825-2833
The role secretory IgM has in protecting splenic tissue from LPS-induced damage was assessed in mice incapable of secreting IgM but able to express surface IgM and IgD. Within seconds after LPS challenge, 99% of the (131)I-labeled LPS was found in th
Publikováno v:
Journal of Leukocyte Biology. 80:816-826
As the phenotype of adult dermal stem cells is still elusive, and the hematopoietic stem cell is one of the best-characterized stem cells in the body, we tested dermal cell suspensions, sections, and wholemounts in newborn and adult mice for hematopo
Autor:
Karin Pfisterer, Andreas Reinisch, Nousheen Iram, Adelheid Elbe-Bürger, Christine Vaculik, Dirk Strunk, Christopher Schuster, Gero Kramer, Wolfgang Bauer
Publikováno v:
The Journal of Investigative Dermatology
Multipotent mesenchymal stromal cells (MSCs) are found in a variety of adult tissues including human dermis. These MSCs are morphologically similar to bone marrow-derived MSCs, but are of unclear phenotype. To shed light on the characteristics of hum
Autor:
Jianzhu Chen, Christine Vaculik, Udo Losert, A. Soleiman, Genya Yanagida, David Hollemann, Michael B. Fischer, Beate M. Rüger
Publikováno v:
Clinical and experimental immunology. 151(1)
Summary The role of secretory IgM in protecting kidney tissue from immune complex glomerulonephritis induced by 4 mg horse spleen apoferritin and 0·05 mg lipopolysaccharide has been investigated in mutant mice in which B cells do not secrete IgM, bu
Autor:
Florian Göbel, Adelheid Elbe-Bürger, Christine Vaculik, Sabine Taschner, Darina Waltenberger, Herbert Strobl, Mario Kumerz
Publikováno v:
Blood. 110:4072-4072
CD34+ cord blood progenitors can develop into interstitial/dermal (int) dendritic cells (DC) and Langerhans cells (LC). IL-4 induces common progenitors to differentiate into intDC and suppresses TGF-β1-dependent LC. The transcriptional mechanisms un