Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christine V. Sapan"'
Review of methods for determination of total protein and peptide concentration in biological samples
Autor:
Christine V. Sapan, Roger L. Lundblad
Publikováno v:
PROTEOMICS - Clinical Applications. 9:268-276
Clinical proteomics can be defined as the use of proteomic technologies to identify and measure biomarkers in fluids and tissues. The current work is intended to review various methods used for the determination of the total concentration of protein
Autor:
Chris C. Tang, Peter A. LeWitt, Kathleen L. Poston, Andrew Feigin, Matthew J. During, Jaimie M. Henderson, Mustafa S. Siddiqui, David Eidelberg, Maureen A. Leehey, Steven G. Ojemann, Alice W. Flaherty, Stephen B. Tatter, Emad N. Eskandar, Jason M. Schwalb, Sandra K. Kostyk, Martin Niethammer, Roger Kurlan, Irene H. Richard, Ali R. Rezai, Atom Sarkar, Michael G. Kaplitt, Christine V. Sapan
BACKGROUND. We report the 12-month clinical and imaging data on the effects of bilateral delivery of the glutamic acid decarboxylase gene into the subthalamic nuclei (STN) of advanced Parkinson's disease (PD) patients. METHODS. 45 PD patients were en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572a23197004ab897af1d757a33c9826
https://europepmc.org/articles/PMC5374069/
https://europepmc.org/articles/PMC5374069/
Autor:
Roger Kurlan, Mustafa S. Siddiqui, Jason M. Schwalb, Kathleen L. Poston, Sandra K. Kostyk, Jaimie M. Henderson, Matthew J. During, Andrew Feigin, Peter A. LeWitt, Karen Thomas, Atom Sarkar, Ali R. Rezai, Alice W. Flaherty, Lori Van Meter, Steven G. Ojemann, Michael G. Kaplitt, Stephen B. Tatter, Emad N. Eskandar, Christine V. Sapan, Maureen A. Leehey, Irene H. Richard
Publikováno v:
The Lancet Neurology. 10:309-319
Summary Background Gene transfer of glutamic acid decarboxylase ( GAD ) and other methods that modulate production of GABA in the subthalamic nucleus improve basal ganglia function in parkinsonism in animal models. We aimed to assess the effect of bi
Autor:
Helen L. Fitzsimons, Veronique Riban, Jennifer L. Wendelken, Ross J. Bland, Christine V. Sapan, Matthew J. During
Publikováno v:
The Journal of Gene Medicine. 12:385-398
Background The steps necessary to translate promising new biological therapies to the clinic are poorly documented. For gene therapy, there are unique aspects that need to be addressed in biodistribution studies. Notably, the spread of the vector bey
Autor:
William T. Shearer, Christine V. Sapan, Lynne M. Mofenson, George J. Nemo, Paul Palumbo, Courtney V. Fletcher, William A. Meyer, Mary Glenn Fowler, Elaine M. Sloand, Diane W. Wara, Lynette Purdue, Pamela Bouquin, Terry Fenton, Yvonne J. Bryson, Ann Petru, E. Richard Stiehm, Elizabeth Hawkins, Minhee Kang, Sandra K. Burchett, Stuart E. Starr
Publikováno v:
The Journal of Infectious Diseases. 181:548-554
The clinical, immunologic, and virologic effects and the pharmacokinetics of human immunodeficiency virus (HIV) human hyperimmune immunoglobulin (HIVIG) were assessed in 30 HIV-infected children aged 2-11 years. All had moderately advanced disease wi
Autor:
Christine V, Sapan, Roger L, Lundblad
Publikováno v:
Cancer genomicsproteomics. 3(3-4)
Blood is the most common source of biomarkers for use in the diagnosis and prognosis of malignant disease. Utilizing proteomic technology for biomarker identification offers greatly increased sensitivity. Such an increase in sensitivity requires prec
Autor:
Thomas D. Schiano, Norah A. Terrault, Christine V. Sapan, Yufeng Li, Timothy L. Pruett, Laura Riser, David R. Nelson, Gary L. Davis, John W. Gnann, Richard J. Whitley, Courtney V. Fletcher
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 11(8)
Chronic hepatitis C is the most common indication for liver transplantation, but viral recurrence is universal and progressive graft injury occurs in most recipients. Our aim was to assess the safety, pharmacokinetics (PK), and antiviral effects of h
Autor:
Deborah Hayes, John R. Mascola, Hermann Katinger, Gabriela Stiegler, Mark K. Louder, Christine V. Sapan, Thomas C. VanCott, Merlin L. Robb, Yichen Lu, Deborah L. Birx, Dawn Harris, Mark G. Lewis, Sarah Schlesinger Frankel, Charles R. Brown
Publikováno v:
Journal of virology. 73(5)
The role of antibody in protection against human immunodeficiency virus (HIV-1) has been difficult to study in animal models because most primary HIV-1 strains do not infect nonhuman primates. Using a chimeric simian/human immunodeficiency virus (SHI
Autor:
Mary Glenn Fowler, Christine V. Sapan, Bonnie J. Mathieson, Jorge Gandia, Lynne M. Mofenson, Eleanor Jimenez, John Moye, Jean Whitehouse, Hunter Hammill, William A. Meyer, George J. Nemo, John S. Lambert, Alice Stek, E. Richard Stiehm, William T. Shearer, Robert P. Nugent, Mary Jo O'Sullivan, Gwendolyn B. Scott, James Bethel, James Korelitz, Andrea Kovacs, Patricia Reichelderfer
Publikováno v:
The Journal of infectious diseases. 179(3)
Pediatric AIDS Clinical Trials Group protocol 185 evaluated whether zidovudine combined with human immunodeficiency virus (HIV) hyperimmune immunoglobulin (HIVIG) infusions administered monthly during pregnancy and to the neonate at birth would signi