Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christine Tso"'
Autor:
Gunjan Sharma, Tiffany M. Tran, Ishu Bansal, Mohammad Sabique Beg, Ruchi Bhardwaj, Jaspal Bassi, Yuande Tan, Amit Kumar Jaiswal, Christine Tso, Ayushi Jain, Jay Singh, Parthaprasad Chattopadhyay, Archna Singh, Anita Chopra, Sameer Bakhshi, David Casero, Dinesh S. Rao, Jayanth Kumar Palanichamy
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Acute lymphoblastic leukemia (ALL) is the most common pediatric hematological malignancy, with ETV6::RUNX1 being the most prevalent translocation whose exact pathogenesis remains unclear. IGF2BP1 (Insulin-like Growth Factor 2 Bind
Externí odkaz:
https://doaj.org/article/a125d7d6927e459099c0c52bba351a83
Autor:
Jayanth Kumar Palanichamy, Tiffany M. Tran, Jennifer K. King, Sol Katzman, Alexander J. Ritter, Gunjan Sharma, Christine Tso, Jorge R. Contreras, Thilini R. Fernando, Jeremy R. Sanford, Dinesh S. Rao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Loss of function in the tumor suppressor gene TP53 is the most common alteration seen in human cancer. In mice, P53 deletion in all cells leads predominantly to the development of T-cell lymphomas, followed by B-cell lymphomas, sarcomas and
Externí odkaz:
https://doaj.org/article/d4d856ddeb78490fb274068a06234553
Autor:
Gunjan Sharma, Tiffany M Tran, Jaspal Bassi, Yuande Tan, Amit Kumar Jaiswal, Christine Tso, Ayushi Jain, Jay Singh, Anita Chopra, Archna Singh, Sameer Bakhshi, Parthaprasad Chattopadhyay, David Casero, Dinesh Subba Rao, Jayanth Kumar Palanichamy
Background ETV6-RUNX1 is the most prevalent translocation in pediatric B-ALL (B-cell Acute Lymphoblastic Leukemia). However, the exact pathogenesis of this translocation leading to leukemogenesis remains unclear. Insulin like Growth Factor 2 Binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591e1ac7b9052cc91368f7c56a89910a
https://doi.org/10.21203/rs.3.rs-1691465/v1
https://doi.org/10.21203/rs.3.rs-1691465/v1
Autor:
Tiffany M. Tran, Jaspal Bassi, Anita Chopra, Jay Singh, Archna Singh, Jayanth Kumar Palanichamy, Ayushi Jain, Sameer Bakhshi, Amit Kumar Jaiswal, Christine Tso, Gunjan Sharma, Dinesh S. Rao
Publikováno v:
Blood. 138:3483-3483
Acute lymphoblastic leukaemia (ALL) is the most common pediatric haematological malignancy with a prevalence of around 85% cases of B cell origin. ETV6-RUNX1 is the most common genetic aberration in childhood B-ALL with a prevalence of around 25% in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f66ece1e14cd2326c9e04fd05c1670
https://doi.org/10.1182/blood-2021-150319
https://doi.org/10.1182/blood-2021-150319
Autor:
J. King, Thilini Fernando, Tiffany M. Tran, Jayanth Kumar Palanichamy, Jeremy R. Sanford, Christine Tso, Jorge R. Contreras, Sol Katzman, Gunjan Sharma, Dinesh S. Rao
Publikováno v:
Blood. 138:2229-2229
Deletion of the tumor suppressor gene TP53 (Trp53 in mice) has been associated with the development of numerous human malignancies. TP53 acts as a central coordinator of the DNA damage response. In mice, pan-Trp53 deletion leads predominantly to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ebeab49609221527f19252c0a5b00ed
https://doi.org/10.1182/blood-2021-150931
https://doi.org/10.1182/blood-2021-150931