Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Christine T.N. Pham"'
Autor:
Huimin Yan, Ying Hu, Antonina Akk, Muhammad Farooq Rai, Hua Pan, Samuel A. Wickline, Christine T.N. Pham
Publikováno v:
Pharmaceutics, Vol 12, Iss 1, p 73 (2020)
Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or
Externí odkaz:
https://doaj.org/article/e5a2a89b381e4b91a56c78e6d42b7058
Autor:
Rui Tang, Gail Sudlow, Shaw-Wei D. Tsen, Christine T.N. Pham, Kexian Liang, Samuel Achilefu, Luke E. Springer, Krishna Sharmah Gautam, Amir Kucharski
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background The development and optimization of therapies for rheumatoid arthritis (RA) is currently hindered by a lack of methods for early non-invasive monitoring of treatment response. Annexin A2, an inflammation-associated protein whose presence a
Autor:
Luke E. Springer, Natalia S. Harasymowicz, Alison K. Ross, Chia-Lung Wu, Lara Pferdehirt, Jonathan M. Brunger, Kelsey H. Collins, Franklin T. Moutos, Farshid Guilak, Yun-Rak Choi, Christine T.N. Pham
Publikováno v:
Science advances. 7(36)
Biologic drug therapies are increasingly used for inflammatory diseases such as rheumatoid arthritis but may cause significant adverse effects when delivered continuously at high doses. We used CRISPR-Cas9 genome editing of iPSCs to create a syntheti
Autor:
Serge Mazères, Stephen Adonai Leon-Icaza, Mohamed Lamkanfi, Karin Santoni, Christine T.N. Pham, Jean-Philippe Girard, Etienne Meunier, Emilie Doz-Deblauwe, Audrey Hessel, Odile Burlet-Schiltz, Christophe Paget, David Péricat, Aylward F, Yoann Rombouts, Anne Gonzalez-de-Peredo, Salimata Bagayoko, Nathalie Winter, Renaud Poincloux, Pierre-Jean Bordignon, Céline Cougoule, Rémi Planès, Emma Lefrançais, Elisabeth Bellard, Miriam Pinilla, Abdderrahim R
Multiple neutrophil death programs contribute to host defense against infections. Although expressing all necessary components, neutrophils specifically fail to undergo pyroptosis, a lytic form of cell death triggered by the activation of the pro-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f99cee53f9a193b6ca7c112e8123483
https://doi.org/10.1101/2021.06.28.450116
https://doi.org/10.1101/2021.06.28.450116
Autor:
Ying Shiang Lim, Haina Shin, Maxim N. Artyomov, Xiaoping Jiang, Ayşe Naz Ozantürk, Jason Scott, Tania Lebratti, Adjoa Cofie, Regina A. Clemens, Prabhakar S. Andhey, Christine T.N. Pham, Maria Rita Fabbrizi, Mary C. Dinauer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7115540d0ac6f479e3376f9695a116
https://doi.org/10.7554/elife.65762.sa2
https://doi.org/10.7554/elife.65762.sa2
Autor:
Samuel A. Wickline, Hua Pan, A. Kucharski, A. MacAlinden, Regis J. O'Keefe, X. Li, Jie Shen, Christine T.N. Pham
Publikováno v:
Osteoarthritis and Cartilage. 29:S13-S14
Autor:
Luke E. Springer, Samuel Achilefu, Megan S. Michie, Christine T.N. Pham, Baogang Xu, Gail Sudlow
Publikováno v:
J Photochem Photobiol A Chem
Near-infrared (NIR) dye-peptide conjugates are widely used for tissue-targeted molecular fluorescence imaging of pathophysiologic conditions. However, the significant contribution of both dye and peptide to the net mass of these bioconjugates implies
Autor:
Alexandra L. Davis, Young Guang, Tom M. McGrath, Christine T.N. Pham, Lori A. Setton, James A. J. Fitzpatrick
Publikováno v:
Ann Biomed Eng
Intra-articular drug delivery can be effective in targeting a diseased joint but is hampered by rapid clearance times from the diarthrodial joint. The synovium is a multi-layered tissue that surrounds the diarthrodial joint and governs molecular tran
Autor:
Jonas Schmidt, Alexia Carré, Veronica C. Ardi, Tomoki Muramatsu, Elena I. Deryugina, Christine T.N. Pham, James P. Quigley
Publikováno v:
iScience
iScience, Vol 23, Iss 12, Pp 101799-(2020)
iScience, Vol 23, Iss 12, Pp 101799-(2020)
Summary Functional roles of neutrophil elastase (NE) have not been examined in distinct steps of the metastatic cascade. NE, delivered to primary tumors as a purified enzyme or within intact neutrophils or neutrophil granule content, enhanced human t