Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Christine T. N. Pham"'
Autor:
Qingyu Zhou, John C. Harding, Ping Fan, Ivan Spasojevic, Attila Kovacs, Antonina Akk, Adam Mitchell, Luke E. Springer, Joseph P. Gaut, Daniel A. Rauch, Samuel A. Wickline, Christine T. N. Pham, Katherine Fuh, Hua Pan
Publikováno v:
Nanomaterials, Vol 14, Iss 21, p 1752 (2024)
Nanomedicine holds great potential for revolutionizing medical treatment. Ongoing research and advancements in nanotechnology are continuously expanding the possibilities, promising significant advancements in healthcare. To fully harness the potenti
Externí odkaz:
https://doaj.org/article/065f548de32f4785bba0977573db983a
Autor:
Shaw-Wei D. Tsen, Luke E. Springer, Krishna Sharmah Gautam, Rui Tang, Kexian Liang, Gail Sudlow, Amir Kucharski, Christine T. N. Pham, Samuel Achilefu
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background The development and optimization of therapies for rheumatoid arthritis (RA) is currently hindered by a lack of methods for early non-invasive monitoring of treatment response. Annexin A2, an inflammation-associated protein whose p
Externí odkaz:
https://doaj.org/article/c2748d36fa21481a93859a9c27874953
Autor:
Sira C. Günther, Carles Martínez-Romero, Milagros Sempere Borau, Christine T. N. Pham, Adolfo García-Sastre, Silke Stertz
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Influenza A virus (IAV) coopts numerous host factors for efficient replication. The cysteine protease cathepsin W (CTSW) has been identified as one host factor required for IAV entry, specifically for the escape of IAVs from late endosomes.
Externí odkaz:
https://doaj.org/article/328d2796bc78464390cf1a5669260d23
Autor:
Qingyu Zhou, James D. Quirk, Ying Hu, Huimin Yan, Joseph P. Gaut, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6086 (2023)
For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10–20% of all cancer patients. Although nephrotoxicity associated with platinum-based agents is well recognized, treatment o
Externí odkaz:
https://doaj.org/article/73988d586d6d4f86bd59788afe442721
Autor:
Kelsey H. Collins, Lara Pferdehirt, Leila S. Saleh, Alireza Savadipour, Luke E. Springer, Kristin L. Lenz, Dominic M. Thompson, Sara J. Oswald, Christine T. N. Pham, Farshid Guilak
Publikováno v:
Gels, Vol 9, Iss 2, p 169 (2023)
Biologic therapies have revolutionized treatment options for rheumatoid arthritis (RA) but their continuous administration at high doses may lead to adverse events. Thus, the development of improved drug delivery systems that can sense and respond co
Externí odkaz:
https://doaj.org/article/48dbb634038f487db13c04368d0f109b
Autor:
Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E. Springer, Ping Fan, Ivan Spasojevic, Ganesh V. Halade, Huanghe Yang, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 336 (2022)
Cancer treatment-induced toxicities may restrict maximal effective dosing for treatment and cancer survivors’ quality of life. It is critical to develop novel strategies that mitigate treatment-induced toxicity without affecting the efficacy of ant
Externí odkaz:
https://doaj.org/article/dcc9257127ab4ef79e27f0f7a34e4b4c
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa
Autor:
Karin Santoni, David Pericat, Leana Gorse, Julien Buyck, Miriam Pinilla, Laure Prouvensier, Salimata Bagayoko, Audrey Hessel, Stephen Adonai Leon-Icaza, Elisabeth Bellard, Serge Mazères, Emilie Doz-Deblauwe, Nathalie Winter, Christophe Paget, Jean-Philippe Girard, Christine T. N. Pham, Céline Cougoule, Renaud Poincloux, Mohamed Lamkanfi, Emma Lefrançais, Etienne Meunier, Rémi Planès
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2022, 18 (7), pp.e1010305. ⟨10.1371/journal.ppat.1010305⟩
PLoS Pathogens, 2022, 18 (7), 29 p. ⟨10.1371/journal.ppat.1010305⟩
PLoS Pathogens, 2022, 18 (7), pp.e1010305. ⟨10.1371/journal.ppat.1010305⟩
PLoS Pathogens, 2022, 18 (7), 29 p. ⟨10.1371/journal.ppat.1010305⟩
Multiple regulated neutrophil cell death programs contribute to host defense against infections. However, despite expressing all necessary inflammasome components, neutrophils are thought to be generally defective in Caspase-1-dependent pyroptosis. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0443464c177471888f83b97782e1d77
https://hal.inrae.fr/hal-03738417/file/2022_Santoni_Plos-Pathog_vol-18.pdf
https://hal.inrae.fr/hal-03738417/file/2022_Santoni_Plos-Pathog_vol-18.pdf
Autor:
Muhammad Farooq Rai, Linda J. Sandell, Huimin Yan, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
Transl Res
RNA interference (RNAi) is a cellular mechanism for post-transcriptional gene regulation mediated by small interfering RNA (siRNA) and microRNA. siRNA-based therapy holds significant promise for the treatment of a wide-range of arthritic diseases. si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2c2f92425e8f619a1a3a4c39a5b096
https://doi.org/10.1016/j.trsl.2019.07.002
https://doi.org/10.1016/j.trsl.2019.07.002
Autor:
Molly Klimak, Dakota B Katz, Lara Pferdehirt, Alison K. Ross, Farshid Guilak, Suzanne M. Tabbaa, Christine T. N. Pham, Yun-Rak Choi, KelseyH Collins, Robert J. Nims
Publikováno v:
J Orthop Res
Stem cells provide tremendous promise for the development of new therapeutic approaches for musculoskeletal conditions. In addition to their multipotency, certain types of stem cells exhibit immunomodulatory effects that can mitigate inflammation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c9440717d4991e26adb7a6c5852a5b
https://doi.org/10.1002/jor.24304
https://doi.org/10.1002/jor.24304
Autor:
Hua Pan, Luke E. Springer, Farshid Guilak, Huimin Yan, Kelsey H. Collins, Samuel A. Wickline, Christine T. N. Pham, M. Farooq Rai, Xin Duan
Publikováno v:
Precision Nanomedicine
Inflammation after joint injury leads to joint responses that result in eventual osteoarthritis development. Blockade of inflammation, by suppressing NF-κB expression, has been shown to reduce joint injury-induced chondrocyte apoptosis and reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62e145eb1834bcb89966bd817ce9080
https://doi.org/10.33218/prnano2(1).181129.1
https://doi.org/10.33218/prnano2(1).181129.1