Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Christine Sumner"'
1
Animal Dissection vs. Non-Animal Teaching Methods
Autor: Elisabeth Ormandy, Janella C. Schwab, Samantha Suiter, Nicole Green, Janice Oakley, Pamela Osenkowski, Christine Sumner
Publikováno v: The American Biology Teacher. 84:399-404
Animal dissection is practiced to varying degrees around the world and is particularly prevalent in North America throughout all levels of education. However, a growing number of studies suggest that non-animal teaching methods (NAMs) (e.g., virtual
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da88dfe739c3190e00607f6dbd86ad29
https://doi.org/10.1525/abt.2022.84.7.399
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2
Abstract 3528: Novel enzymatic DNA fragmentation integrated into library construction
Autor: Vaishnavi Panchapakesa, Pingfang Liu, Lynne Apone, Chen Song, Fiona J. Stewart, Eileen T. Dimalanta, Timur Shtatland, Bradley W. Langhorst, Theodore B. Davis, Christine Sumner, Christine Rozzi, Karen Duggan
Publikováno v: Cancer Research. 79:3528-3528
Next Generation Sequencing (NGS) is rapidly becoming a powerful tool, by providing a high resolution and global view of the cancer genome mainly through whole genome, whole exome and transcriptome sequencing. This knowledge is important to support dr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55ae6db1b3c9544883c9e37af707a83e
https://doi.org/10.1158/1538-7445.am2019-3528
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3
Selective Depletion of Abundant RNAs to Enable Transcriptome Analysis of Low‐Input and Highly Degraded Human RNA
Autor: Barton E. Slatko, Theodore B. Davis, Salvatore Russello, Christine L. Chater, Daniela B. Munafo, Fiona J. Stewart, Andrew F. Gardner, Christine Sumner, Deyra N. Rodriguez, John Morlan, Dominick Sinicropi, Kunbin Qu, Bradley W. Langhorst, Eileen T. Dimalanta
Publikováno v: Current Protocols in Molecular Biology
Ribosomal RNAs (rRNAs) are extremely abundant, often constituting 80% to 90% of total RNA. Since rRNA sequences are often not of interest in genomic RNA sequencing experiments, rRNAs can be removed from the sample before the library preparation step,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3cf87c8dfb570d8664a58e4331f56d
https://doi.org/10.1002/0471142727.mb0722s113
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6
Abstract 3628: Improving sequencing quality of libraries prepared from FFPE DNA
Autor: Eileen T. Dimalanta, Christine Sumner, Evans C. Thomas, Pingfang Liu, Fiona J. Stewart, Laurence Ettwiller, Lixin Chen, Theodore B. Davis
Publikováno v: Cancer Research. 76:3628-3628
Targeted cancer therapy based on genomic alterations can be remarkably effective, and has made significant strides with the recent advances in next-generation sequencing (NGS) technology. Although samples of blood and other bodily fluids are being ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acbfbe682d4e08b5d8b24454dbb7a696
https://doi.org/10.1158/1538-7445.am2016-3628
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7
Abstract 3620: Enhancing clinical utility of NGS with reduced bias, low DNA input, library construction
Autor: Joanna Bybee, Danielle Rivizzigno, Lynne Apone, Laurie Mazzola, Krishnan Keerthana, Eileen T. Dimalanta, Nicole M. Nichols, Pingfang Liu, Vaish Panchapakesa, Theodore B. Davis, Julie F. Menin, Karen Duggan, Fiona J. Stewart, Deyra N. Rodriguez, Christine L. Chater, Christine Sumner, Yanxia Bei, Brad Langhorst
Publikováno v: Cancer Research. 76:3620-3620
Early detection and diagnosis of cancer substantially increases the likelihood for successful treatment. Tools that aid in detecting and diagnosing cancer early, therefore, have the potential to greatly impact the clinical outcome for cancer patients
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d01cc944f18ef180841861b77710faa3
https://doi.org/10.1158/1538-7445.am2016-3620
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8
A fast solution to NGS library preparation with low nanogram DNA input
Autor: Theodore B. Davis, Erbay Yigit, Lynne Apone, Christine Sumner, Gregory J. S. Lohman, Daniela B. Munafo, Fiona J. Stewart, Thomas C. Evans, Nicole M. Nichols, Bradley W. Langhorst, Eileen T. Dimalanta, Pingfang Liu, Eric J. Cantor
Publikováno v: BMC Proceedings, Vol 6, Iss Suppl 6, p P26 (2012)
BMC Proceedings
Next Generation Sequencing (NGS) has significantly impacted human genetics, enabling a comprehensive characterization of the human genome as well as a better understanding of many genomic abnormalities. By delivering massive DNA sequences at unpreced
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2729e61bc915cc84779891c97a86231c
https://doi.org/10.1186/1753-6561-6-s6-p26
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9
Comparative analysis of strand-specific RNA sequencing approaches
Autor: Christine Sumner, Lynne Apone, Theodore B. Davis, Brad Langhorst, Erbay Yigit, Daniela B. Munafo, Fiona J. Stewart, Eileen T. Dimalanta, Ping Liu, Landon Merrill
Publikováno v: BMC Proceedings, Vol 6, Iss Suppl 6, p P30 (2012)
BMC Proceedings
Background Standard RNA sequencing approaches generally require double-stranded cDNA synthesis, which erases RNA strand information. Synthesis of a randomly primed double-stranded cDNA followed by addition of adaptors for next-generation sequencing l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d5a39073922cea5c7d91f4ce05e199
https://doi.org/10.1186/1753-6561-6-s6-p30
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10
Abstract 4886: Repair of challenging FFPE DNA improves library success rate and sequencing quality
Autor: Christine Sumner, Laurence Ettwiller, Eileen T. Dimalanta, Theodore B. Davis, Fiona J. Stewart, Thomas C. Evans, Pingfang Liu, Lixin Chen
Publikováno v: Cancer Research. 75:4886-4886
Formalin-fixed, paraffin-embedded (FFPE) clinical samples are an invaluable source of information about genetic alterations in human disease, especially cancer. Next generation sequencing is a powerful tool to mine that information. Unfortunately, se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e527ca8b532644ceda9f5d8640b93cce
https://doi.org/10.1158/1538-7445.am2015-4886
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