Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christine Southgate"'
Autor:
Douglas F. Easton, Kenneth Muir, Gianluca Severi, Sarah Bullock, Ketil Heimdal, Richard S. Houlston, William D. Foulkes, Questa Hope, David P. Dearnaley, Lovise Maehle, Stephen M. Edwards, Sameer Jhavar, David Roquis, James C. Engert, Christine Southgate, Daniel Sinnett, Nancy Hamel, Michael D. Badzioch, Jacques Simard, Melissa C. Southey, Alison Falconer, A Dowe, Graham G. Giles, John L. Hopper, Christopher H. Evans, Pål Møller, Rosalind A. Eeles, Dallas R. English, Julia C. Meitz
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 14:397-402
Background: Variants in the gene encoding the macrophage scavenger receptor 1 (MSR14) protein have been identified in men with prostate cancer, and several small studies have suggested that the 999C>T (R293X) protein-truncating mutation may be associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786c83fb683a29c19060457339042e4e
https://doi.org/10.1158/1055-9965.epi-04-0202
https://doi.org/10.1158/1055-9965.epi-04-0202
Autor:
Brigitte Chapot, Norman Moullan, Audrey Ardern-Jones, Sandra Angèle, A. R. Norman, Richard S. Houlston, David P. Dearnaley, Christine Southgate, Michael Bremer, S Bullock, Stephen M. Edwards, Julia C. Meitz, Q Hope, A Dowe, Janet Hall, Thilo Dörk, Kenneth Muir, Rosalind A. Eeles, Doug Easton, A Falconer
Publikováno v:
British Journal of Cancer
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
The risk of prostate cancer is known to be elevated in carriers of germline mutations in BRCA2, and possibly also in carriers of BRCA1 and CHEK2 mutations. These genes are components of the ATM-dependent DNA damage signalling pathways. To evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da5581b38a5fc84de83c2ca4b0dd4b
http://europepmc.org/articles/PMC2364767
http://europepmc.org/articles/PMC2364767
Autor:
W.M. Howell, Doug Easton, David P. Dearnaley, Philip R. Evans, Rosalind A. Eeles, A Dowe, Sarah L. McCarron, Audrey Ardern-Jones, Christine Southgate, S. Edwards
Publikováno v:
British Journal of Cancer. 86:20-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f37a5f40e2634043d9dbf1ebe2cccd
https://doi.org/10.1038/sj.bjc.6600405
https://doi.org/10.1038/sj.bjc.6600405
Autor:
A Dowe, Rosalind A. Eeles, Christine Southgate, Richard S. Houlston, David P. Dearnaley, Steve Bevan, A Ardern Jones, Stephen M. Edwards, Doug Easton
Publikováno v:
Prostate Cancer and Prostatic Diseases. 6:12-14
Inherited susceptibility to prostate cancer has been linked to a number of chromosomal regions, however no genes have been unequivocally shown to underlie reported linkages. The putative gene localised to chromosome 1q42-q43, has been designated PCaP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc258a2c950eff569aec123b5a94e44
https://doi.org/10.1038/sj.pcan.4500616
https://doi.org/10.1038/sj.pcan.4500616
Autor:
Andrew Dodson, Sameer Jhavar, Rosalind A. Eeles, Colin Cooper, David P. Dearnaley, Christopher S. Foster, A Dowe, Alison Falconer, Nening Dennis, Andrew Feber, Andrew R. Norman, Christine Southgate, A Fletcher
Publikováno v:
Oncogene. 23(35)
E2F transcription factors, including E2F3, directly modulate expression of EZH2. Recently, overexpression of the EZH2 gene has been implicated in the development of human prostate cancer. In tissue microrarray studies we now show that expression of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af270daafaca3c6340af2d16072e37d2
https://pubmed.ncbi.nlm.nih.gov/15184867
https://pubmed.ncbi.nlm.nih.gov/15184867
Autor:
Sarah L, McCarron, Stephen, Edwards, Philip R, Evans, Roz, Gibbs, David P, Dearnaley, Anna, Dowe, Christine, Southgate, Douglas F, Easton, Rosalind A, Eeles, W Martin, Howell
Publikováno v:
Cancer research. 62(12)
Polymorphisms in the promoter regions of cytokine genes may influence prostate cancer (PC) development via regulation of the antitumor immune response and/or pathways of tumor angiogenesis. PC patients (247) and 263 controls were genotyped for interl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8994761deebbcaa4ebe5267442c936d7
https://pubmed.ncbi.nlm.nih.gov/12067976
https://pubmed.ncbi.nlm.nih.gov/12067976
Autor:
David P. Dearnaley, Audrey Ardern-Jones, A Murkin, J. Kelly, Zsofia Kote-Jarai, Peter Osin, Julia C. Meitz, Doug Easton, Christine Southgate, Rashmi Singh, A Dowe, Sue Williams, Margaret Stevens, Rosalind A. Eeles, Stephen M. Edwards, Rachel Jackson, Dawn Teare, Rifat Hamoudi, Richard A. Oram, Alison Falconer, A.J. Bruce Ponder, Simon A. Gayther, Questa Hope
Publikováno v:
The American Journal of Human Genetics. (1):1-12
Studies of families with breast cancer have indicated that male carriers of BRCA2 mutations are at increased risk of prostate cancer, particularly at an early age. To evaluate the contribution of BRCA2 mutations to early-onset prostate cancer, we scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2252fbf50ec89d2c5e0c0b5924398fda