Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christine Siepl"'
Autor:
Jürgen Kratzsch, Mohamed El Kholy, Paul Saenger, Jin Hwa Lee, Rajesh Khadgawat, Vaman Khadilkar, Valentina Peterkova, Verónica Mericq, M Desai, Yoon Ju Bae, Elena Bolshova, Hyi-Jeong Ji, E. Christine Siepl, Prema Lopez, Klavdia A. Radjuk, Dieter Martin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:126-132
Sustained-release GH formulations may provide a strategy for improving treatment compliance and persistence in GH-deficient patients.The aim of the study was to examine efficacy and safety of LB03002, a sustained-release GH formulation for once-weekl
Autor:
Catalin Gavrila, Hyi-Jeong Ji, E. Christine Siepl, Christian J. Strasburger, Mihail Coculescu, Vera Popovic, Conrad Savoy, J. Roemmler, Beverly M. K. Biller, David M. Cook, Hyunji Ahn
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:1718-1726
A sustained-release recombinant human GH formulation, LB03002, has been recently developed, with pharmacokinetics and pharmacodynamic activity appropriate for once-weekly administration. LB03002 is a long-acting GH that is administered once a week by
Autor:
Christine Siepl, H. H. Althaus
Publikováno v:
Cell and Tissue Research. 287:135-141
The synthesis and release of prostaglandins have been studied in oligodendrocytes isolated from adult pig brain. Radioactively labelled arachidonic acid and di-homo-y-linoleic acid were offered as precursors and their incorporation into individual ph
Autor:
Catalin Gavrila, Hyunji Ahn, J. Roemmler, David M. Cook, Beverly M. K. Biller, Mihail Coculescu, Hyi-Jeong Ji, Christian J. Strasburger, E. Christine Siepl, Conrad Savoy, Vera Popovic
Publikováno v:
Pituitary. 16(3)
The weekly sustained-release recombinant human GH formulation LB03002, showed beneficial effects in GH-deficient (GHD) adults in a previous 26-week double-blind study. Prior studies of long-acting GH preparations in adults have only been conducted fo
Publikováno v:
Ciba Foundation Symposium 157-Clinical Applications of TGF-β ISBN: 9780470514061
Ciba Foundation Symposium 157-Clinical Applications of TGF-β
Ciba Foundation Symposium 157-Clinical Applications of TGF-β
Glioblastomas are among the most malignant tumours for which no curative treatment exists. A dysfunction of cellular immunity with decreased skin reactivity and lymphocyte blastogenesis has been described in patients with glioblastomas. In culture hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc29cc1f3744ab28a082a4e492eda51a
https://doi.org/10.1002/9780470514061.ch15
https://doi.org/10.1002/9780470514061.ch15
Autor:
Karl Frei, Adriano Fontana, Christine Siepl, Stefan Bodmer, Nicolas De Tribolet, Kevin Strommer, Irma Heid
Publikováno v:
Annals of the New York Academy of Sciences. 593:292-294
Autor:
Erhard Hofer, Renate Hofer-Warbinek, Christine Siepl, Stefan Bodmer, Adriano Fontana, R de Martin, M. Wrann, K Frei
Publikováno v:
The EMBO Journal. 6:1633-1636
T cell suppressor factor produced by human glioblastoma cells inhibits T cell proliferation in vitro and more specifically interferes with interleukin-2 (IL-2)-dependent T cell growth. Here we report the purification of this factor from conditioned m
Publikováno v:
Annals of the New York Academy of Sciences. 540
Autor:
Erhard Hofer, H. Robson MacDonald, Adriano Fontana, Karl Frel, Christine Siepl, Stefan Bodmer, Rainer de Martin
Publikováno v:
European journal of immunology. 18(4)
Human glioblastoma cells secrete a peptide termed glioblastoma-derived T cell suppressor factor (G-TsF) which inhibits T cell activation. Recently, purification and cloning of G-TsF revealed that G-TsF is identical to transforming growth factor-beta
Autor:
Karl Frei, Cornelia Schwerdel, Adriano Fontana, Peter Groscurth, Christine Siepl, Stefan Bodmer
Publikováno v:
European journal of immunology. 17(9)
In this study microglial cells isolated from brain cell cultures of newborn mice were characterized and investigated for morphology, their responses to growth factors and their functional properties. The microglial cells were phagocytic, contained no