Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christine Schorn"'
Autor:
Christine Schorn, Luis E. Muñoz, Martin Herrmann, Milos R. Filipovic, Georg Schett, Ivana Ivanović-Burmazović, Christina Janko
Publikováno v:
Antioxidants & Redox Signaling. 20:1075-1085
Significance: In the cells' nuclei, high-mobility group box protein 1 (HMGB1) is a nonhistone chromatin-binding protein involved in the regulation of transcription. Extracellularly, HMGB1 acts as a danger molecule with properties of a proinflammatory
Autor:
Christian Maueröder, Christian Berens, Luis E. Muñoz, Udo S. Gaipl, Christina Janko, Rostyslav Bilyy, Georg Schett, Christine Schorn, Benjamin Frey, Ricardo A. Chaurio
Publikováno v:
Autoimmunity. 46:317-322
The presence of a solid tumor is the result of a complex balance between rejection, tolerance and regeneration in which the interactions of tumor cells with cells of the host immune system contribute strongly to the final outcome. Here we report on a
Publikováno v:
Autoimmunity. 45:593-596
Evidences accumulated that the death of neutrophils are not the end of their missions. The neutrophil extracellular traps (NETs), web-like structure, formed after neutrophils dying contribute greatly to immune defense, in both innate and adaptive imm
Autor:
S Herman, Angelika Kny, Rikard Holmdahl, Birgit Niederreiter, Christine Schorn, Jürgen Pfatschbacher, Günter Steiner, Martin Herrmann, Markus H. Hoffmann
Publikováno v:
Autoimmunity. 45:602-611
Hydrocarbon oils such as pristane or hexadecane induce arthritis and lupus in rodents sharing clinical and pathological features with the human diseases rheumatoid arthritis and systemic lupus erythematosus, respectively. In pristane-induced lupus in
Autor:
Roland Wunderlich, Ludwig Keilholz, Barbara Lödermann, Silke Frey, Franz Rödel, Christine Schorn, Rainer Fietkau, Sonja Stangl, Benjamin Frey, Udo S. Gaipl
Publikováno v:
International Journal of Radiation Biology
Therapy with low doses of ionising radiation (X-rays) exerts anti-inflammatory effects. Little is known about whether and how low doses of X-ray treatment modulate the inflammatory phenotype of macrophages, especially the secretion of Interleukin-1be
Autor:
Christine Schorn, Connie Schulze, Georg Schett, Luis E. Muñoz, Martin Herrmann, Kerstin Sarter, Christina Janko
Publikováno v:
Autoimmunity Reviews. 10:38-42
Systemic lupus erythematosus (SLE) is an autoimmune disease with very prominent chronic inflammatory aspects that render into multiple symptoms and clinical signs. The precise etiology of SLE remains elusive; however, it is known that its etiopathoge
Autor:
Martin Herrmann, Silke Winkler, S. Muller, Georg Schett, Hj Gabius, Martin Schiller, Christine Schorn, Laura Andreoli, Aa Manfredi, Da Isenberg, Jean-Paul Briand, Le Munoz, Christina Janko, Sabine André
Publikováno v:
Lupus; Vol 21
Lupus
Lupus
Autoantibodies against opsonins of dying and dead cells mediate Fcγ receptor-dependent phagocytosis of autologous apoptotic and necrotic cells and hereby tend to elicit inflammation instead of silent clearance. We analysed sera of patients with chro
Autor:
Christine Schorn, Martin Herrmann, Connie Schulze, Moritz Strysio, Georg Schett, Christina Janko, Luis E. Muñoz
Publikováno v:
Autoimmunity. 42:314-316
Uric acid (UA) is identified as a danger signal released from dying cells. It precipitates in sodium-rich extracellular fluid and in potassium-rich intracellular fluid as monosodium urate (MSU) and monopotassium urate (MPU), respectively. Here, we ex
Autor:
Ricardo A. Chaurio, Daniela Weidner, Ahmed Sheriff, Luis E. Muñoz, Christine Schorn, Georg Schett, Christina Janko, Kerstin Sarter
Publikováno v:
Autoimmunity. 42:286-288
CRP is an important inflammatory marker, however, CRP levels are relatively low in patients with SLE. In addition patients with SLE often display low activities and serum levels for DNase I and complement, respectively. Here we show that DNase I trea
Autor:
Christine Schorn, Ricardo A. Chaurio, Christina Janko, Luis E. Muñoz, Ivica Jeremic, Martin Herrmann, Mona H C Biermann
Publikováno v:
Physical biology. 10(6)
Healthy cells exhibit an asymmetric plasma membrane with phosphatidylserine (PS) located on the cytoplasmic leaflet of the plasma membrane bilayer. Annexin A5-FITC, a PS binding protein, is commonly used to evaluate apoptosis in flow cytometry. PS ex