Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation

Autor: Christine Salaun, Hiroya Takizawa, Alex Galindo, Kevin R. Munro, Jayde McLellan, Isamu Sugimoto, Tomotaka Okino, Nicholas C.O. Tomkinson, Luke H. Chamberlain

Publikováno v: The Journal of biological chemistry. 298(10)

Protein S-acylation is a reversible post-translational modification that modulates the localization and function of many cellular proteins. S-acylation is mediated by a family of zinc finger DHHC (Asp-His-His-Cys) domain-containing (zDHHC) proteins e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b96c3029461796d879bea82b6e06ec
https://pubmed.ncbi.nlm.nih.gov/36087837

Substrate selectivity in the zDHHC family of

Autor: Kimon, Lemonidis, Christine, Salaun, Marianna, Kouskou, Cinta, Diez-Ardanuy, Luke H, Chamberlain, Jennifer, Greaves

Publikováno v: Biochemical Society transactions. 45(3)

S-acylation is a reversible lipid modification occurring on cysteine residues mediated by a family of membrane-bound 'zDHHC' enzymes. S-acylation predominantly results in anchoring of soluble proteins to membrane compartments or in the trafficking of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39519abb67d178f2712581dafc7ad2a9
https://pubmed.ncbi.nlm.nih.gov/28620036

Atol: Animal Trait Ontology for Livestock. Atol: Où en sommes-nous ?

Autor: Pierre-Yves Le Bail, Jérôme Bugeon, Olivier Dameron, Alice Fatet, Catherine Hurtaud, Isabelle Hue, Léa Joret, Marie-Christine Salaun, Claire Nédellec, Matthieu Reichstadt, Jean Vernet

Publikováno v: 4. Journées d'Animation Scientifique du département Phase (JAS Phase 2012)
4. Journées d'Animation Scientifique du département Phase (JAS Phase 2012), Jan 2012, Rennes, France. 30 diapositives, 2012
4. Journées d'Animation Scientifique du département Phase (JAS Phase 2012), Institut National de Recherche Agronomique (INRA). UAR Département Physiologie Animale et Systèmes d'Elevage (0558)., Jan 2012, Rennes, France. 30 diapositives
4. Journées d'Animation Scientifique du département Phase (JAS Phase 2012), Jan 2012, Rennes, France. 30 diapositives
HAL

Présentation exposée en PPTPrésentation exposée en PPT; absent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3361842dabd63215965e09d91cdc0f4b
https://hal.archives-ouvertes.fr/hal-01210637

ATOL: A new ontology for livestock

Autor: Catherine Hurtaud, Jérôme Bugeon, Olivier Dameron, Alice Fatet, Isabelle Hue, Marie-Christine Salaun, Matthieu Reichstadt, Alain Valancogne, Jean Vernet, James Reecy, Park, C., Pierre-Yves Le Bail

Publikováno v: ICAR 2011: "New technologies and new challenges for breeding and herd management"
ICAR 2011: "New technologies and new challenges for breeding and herd management", Jun 2011, Bourg-en-Bresse, France
HAL
ICAR 2011: "New technologies and new challenges for breeding and herd management", Jun 2011, Bourg-en-Bresse, France. 2011

Session 2 : phenotyping of complex traitsSession 2 : phenotyping of complex traits; absent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9f65728bda43ad4201c26a2d1da40da9
https://hal.archives-ouvertes.fr/hal-01189518

A new human NHERF1 mutation decreases renal phosphate transporter NPT2a expression by a PTH-independent mechanism.

Autor: Marie Courbebaisse, Christine Leroy, Naziha Bakouh, Christine Salaün, Laurent Beck, Bernard Grandchamp, Gabrielle Planelles, Randy A Hall, Gérard Friedlander, Dominique Prié

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34764 (2012)

BackgroundThe sodium-hydrogen exchanger regulatory factor 1 (NHERF1) binds to the main renal phosphate transporter NPT2a and to the parathyroid hormone (PTH) receptor. We have recently identified mutations in NHERF1 that decrease renal phosphate reab

Externí odkaz: https://doaj.org/article/0255d0a5a6ce4c6c89a90858da2ad581