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pro vyhledávání: '"Christine S. Siska"'
Autor:
David B. Volkin, C. Russell Middaugh, Feng He, Prem S. Thapa, Christine S. Siska, Sangeeta B. Joshi, Paul S. Bullock, Houman Bashiri, Nigel Pheasey, Bruce A. Kerwin, Ozan S. Kumru
Publikováno v:
Journal of Pharmaceutical Sciences. 104:485-494
The structural integrity and conformational stability of a genetically modified live, oncolytic herpes simplex virus (o-HSV) were investigated across a wide pH (5.5-8.0) and temperature (10°C–87.5°C) range. A combination of circular dichroism, in